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41.
M. Paulli F. Locatelli S. Kindl E. Boveri F. Facchetti F. Porta R. Rosso L. Nespoli U. Magrini 《European journal of pediatrics》1992,151(9):672-675
Histochemical and immunohistochemical studies performed in only a few cases of sinus histiocytosis with massive lymphoadenopathy (SHML) indicated that SHML cells belong to themacrophage — histiocyte system, though their exact origin is still uncertain. We analyzed the morphological, antigenic and enzymatic characteristics of the histiocyte-like cells in one paediatric case of SHML (also named Rosai-Dorfman disease). The SHML cells expressed the S-100 protein, lectins concanavalin A, peanut agglutinin andmonocyte-macrophage related antigens CD 11c, CD 14, CD 33, CD 68 and LN 5. Reactivity with other anti-macrophage antibodies (MAC 387, lysozyme, alpha-1 anti-chymotrypsin) was variable. The CD1a antigen was present only in scattered cells, whereas HLA-DR and the HLA-DR associated invariant chain were absent. Cytochemistry demonstrated an intense activity of acid phosphatase and non specific esterase of SHML cells. A large amount of medium sized mononuclear cells were located in the sinuses and intersinusoidal tissue. Our findings suggest that SHML cells have intermediate features between phagocytes and Langerhans cells/interdigitating reticulum cells. The heterogeneity of marker expression on SHML cells might be related to the local content of factors (e.g., cytokines), capable of modulating the phenotype of monocyted and derived cells. 相似文献
42.
剖宫产术致宫缩乏力性大出血防治探讨 总被引:1,自引:1,他引:1
目的 探讨防治剖宫产术致宫缩乏力性大出血的有效方法。方法 选择2003年1月1日~2005年6月1日在该院住院分娩且具有产后宫缩乏力性大出血高危因素及剖宫产指征的孕产妇396例,随机分为高危积极防治组(观察组)及高危常规治疗组(对照组),进行临床对照观察。结果 观察组术中出血、术后2h累计出血及产后宫缩乏力性大出血发生情况明显低于对照组(P〈0.001;P〈0.01)。且观察组产后24h内血红蛋白(FIB)下降明显低于对照组(P〈0.001)有显著性及非常显著性差异。结论 对有宫缩乏力性大出血的剖宫产高危孕产妇采取术前用药预防及术中积极处理相结合能有效防治产后大出血的发生,值得推广。 相似文献
43.
目的探讨急诊胃镜及胃镜下治疗急性上消化道出血的价值。方法总结2003年6月-2008年5月我院79例急性上消化道出血患者采取急诊胃镜检查及治疗并提出体会。结果76例得到了确诊,确诊率为96.2%,69例治疗后未发现有再出血现象,止血成功率为88.2%。结论对急性上消化道出血患者,在条件允许情况下最好行急诊胃镜检查,其诊断率高;明确诊断的同时最好采取内镜下给予止血治疗,内镜下病灶直观,止血效果好。在行急诊胃镜同时要强化术前准备,做好外科手术及抢救准备。 相似文献
44.
A case of Exulceratio simplex (Es) was reported. Fair sized arteries were present in submucosal layer of fundus of the stomach
from which massive arterial hemorrhage occurred due to the erosion caused by two small mucosal defects. 相似文献
45.
A fatal case of sinus histiocytosis with massive lymphadenopathy (SHML) is described in a male patient who presented at 11 years-of-age with swelling of the malar region and nasal obstruction due to the disease and who died aged 28 in uraemic coma following renal involvement. At autopsy SHML tissue extended into the hilum of both lungs and from the retroperitoneal tissue into the pancreas and kidneys. The appearances suggest that the extension of the disease into these organs may have been due to retrograde lymphatic spread from involved lymph nodes. Replacement of the atypical sinus histiocyte by fibrous tissue was seen in the cervical lymph nodes and this may be the usual mode of resolution of the lesion. The nature of SHML is discussed in relation to a possible infectious aetiology and defects in the host immune system. Finally, it is noted that the term 'massive lymphadenopathy' is not applicable to all cases and that sinus histiocytosis is not appropriate for the now frequently recognized extranodal manifestations of the disease. It is proposed that the term 'lymphophagocytic histiocytosis syndrome' should be adopted or that the eponymous title 'Rosai-Dorfman disease' should be used. 相似文献
46.
47.
Hirofumi Ohashi 《Surgery today》1972,2(3-4):156-165
In order to establish the relationship between the degree of intestinal resection and gastric secretion as well as its motility,
experiments were performed on a total of 64 female rats. Gastric juice was collected after pyloric ligature according to Shay.
Gastrointestinal motility was determined with Nylander's technique using51Cr as an indicator. Postoperative gastric hyperacidity was demonstrated when more than 75 per cent of the small intestine
was resected. Gastric emptying was significantly delayed while intestinal motility was only slightly lowered after massive
resection. A delayed gastric emptying was also observed radiographically.
These changes can be explained by postulating that the massive resection of small intestine produces an excessive functional
load on the remaining intestinal segment, which in turn induces a delayed emptying of the stomach through an enterogastric
reflex resulting in an increased acid secretion. 相似文献
48.
49.
目的:分析急性上消化道大量出血的病因及急诊诊断方法,以提高其急诊诊断水平.方法:回顾近十年来收治急性上消化道大量出血患者276例资料,分析急诊诊断方法及结果,并将入院诊断与最后诊断对比.结果:48小时内参与B超检查阳性率50.61%(83/164),胃镜检查阳性率95.24%(100/105),血管造影100%(5/5).入院诊断消化性溃疡、食管胃底静脉曲张破裂、肿瘤、出血性胃炎、贲门黏膜撕裂、血管畸形和Dieulafoy病构成比分别为38.77%、45.65%、8.70%、6.52%、0.36%、0,而最后诊断分别为35.14%、34.78%、21.74%、2.54%、1.45%、4.35%;诊断符合率分别为73.20%、86.46%、20.00%、71.43%、25.00%、0,其中最高是食管胃底静脉曲张破裂,最低是血管畸形和Dieulafoy病.结论:单凭病史作出急性上消化道大量出血的病因诊断可能存在一定误差,非创伤性B超检查有助于病因诊断,急诊胃镜及血管造影检查能作出病因诊断. 相似文献
50.