广西武鸣华侨农场心血管病危险因素的调查研究

对广西武鸣华侨农场4158人进行基线普查,410人进行膳食调查和作8小时夜尿电解质测定,并将高血压低发区广西的资料与高发区的北京作对比.结果显示,体重指数高是高血压一个重要的危险因素,而体重过重又与膳食中摄入碳水化合物和总热量大有关.另一主要的危险因素是钠,膳食中摄入钠高,尿Na和Na/K比值高者,血压水平和高血压的患病率亦高.     

A Ro/SS-A auto-antibody positive mother's infant revealed congenital complete atrioventricular block,followed by insulin dependent diabetes mellitus and multiple organ failure

We experienced a congenital complete atrioventricular block infant who was born from a Ro/SS-A antibody positive mother. Ro/SS-A antibody was also found in this baby which was presumed to be mediated by the maternal placenta. Temporary cardiac pacing was required at birth and pacemaker implantation was performed at 9 months. At 11 months of age, the baby fell into shock and experienced multiple organ failure because of diabetes mellitus-induced coma. The association between congenital complete heart block and the Ro/SS-A antibody is well known. However, the accompaniment of insulin-dependent diabetes mellitus has not been reported previously. As the Ro/SS-A antigen appears in the cytoplasm of many tissues, the possibility of an association between Ro/SS-A antibody and diabetes mellitus is difficult to deny. We report this rare case to draw attention to the possibility that babies who are born from an Ro/SS-A antibody positive mother may develop diabetes mellitus as well as congenital complete heart block.     

胸腰椎骨折脱位157例临床分析

本文报告157例胸腰椎骨折脱位病人,非手术治疗36例,手术治疗116例。作者对临床治疗中的有关问题进行了讨论。     

Assessment in undergraduate psychiatric education

An assessment of medical students' psychiatric performance demonstrated no association between the ability to rate psychopathology or to observe interview behaviour and traditional written methods of academic achievement. This is in accordance with those few studies which have addressed this issue and indicates that there may well be at least three independent skills involved in clinical decision-making: the ability to engage in interpersonal interaction and elicit information; and the ability to acquire and use academic knowledge. This is consistent with work suggesting that maturational and learning processes influence clinical reasoning, and demonstrates that each component should be addressed in assessing students in psychiatry.     

31例活动性肺结核治疗前及治愈后的CT征象分析

目的 探讨抗结核疗前及治愈后活动性肺结核CT征象的变化特点.方法 选取临床治愈的活动性肺结核31例,对比观察活动性肺结核的CT征象转归表现.结果 肺结核活动性CT征象治愈前检出率为100.0%,治疗后检出率为35.5%.活动性CT征象中毛玻璃阴影、节段分布小叶中心结节影、小叶样实变影、树芽征、支气管壁增厚、厚壁空洞和肺实变治疗前检出率分别为87.1%、80.6%、80.1%、61.3%、58.1%、48.4%和32.3%、,治愈后检出率分别为0、19.4%、0、0、12.9%、0和3.2%.治疗前活动性肺结核CT检查可检出多种活动性影像,而疗程结束后上述征象减少并多以单发为主,两者有显著差异（P＜0.01）.结论 CT检查有助于活动性肺结核治疗疗效的判定,并具有较高的敏感度,但特异度较低.     

门诊抗菌药物使用调查

目的了解医院门诊抗菌药物应用情况，为临床合理应用抗菌药物提供依据。方法抽查2006年1月至11月份门诊处方18163张，统计抗菌药物使用情况，并评价其合理性。结果含抗菌药物处方5809张，占总处方数31．98％。头孢菌素类药物使用率最高，其次为喹诺酮类。给药途径主要为口服给药。结论抗菌药物应用基本合理，但使用中存在一些问题，应引起重视。     

产后抑郁症相关因素调查研究

目的探讨产后抑郁症的相关因素.方法采用分层整群抽样方法,对长沙市4所医院300例产后6周复查的初产妇进行Edinburgh产后抑郁量表与自编问卷调查.结果产后抑郁症的发生率为17.3%;产妇年龄、婚姻状况、教育程度与产后抑郁症无关(均P＞0.05),分娩疼痛承受力、分娩方式、新生儿性别、母婴同室、母乳喂养为产后抑郁症的影响因素(P＜0.05、P＜0.01),且分娩方式是产后抑郁症的危险因素,分娩疼痛承受力与母婴同室是保护因素.结论产后抑郁症发生率较高,其影响因素应引起产科工作人员的重视.     

HIV/AIDS痰瘀病机探讨

艾滋病（AIDS-Acquired Immunodeficiency Syndrome）是一种严重危害人类健康、传播速度快、病死率极高的传染病。     

进展性缺血性脑卒中30例临床分析

目的:探讨进展性缺血性脑卒中:30例患者的危险因素。方法:分析了30例进展性缺血性脑卒中患者的血压、血糖、血脂及纤维蛋白原指标与30例非进展性缺血脑卒中患者指标对照,并进行统计学处理。结果:进展性缺血性脑卒中患者合并高血压例数明显高于对照组(P<0.01),血糖,血脂和纤维蛋白原指标也高于对照组(P<0.01,0.05)。结论:高血压,糖尿病,高血脂和高纤维蛋白原血症是进展性缺血性脑卒中的危险因素。     

An alkylpolyglucoside surfactant as a prospective pharmaceutical excipient for topical formulations: The influence of oil polarity on the colloidal structure and hydrocortisone in vitro/in vivo permeation

There is a growing need for research into new skin- and environment-friendly surfactants. This paper focuses on a natural surfactant of an alkylpolyglucoside type, which can form both thermotropic and lyotropic liquid-crystalline phases. The aim of this study was to relate some physicochemical properties (characterised by polarisation and transmission electron microscopy, thermal analysis and rheology) of the three formulations based on cetearyl glucoside and cetearyl alcohol, to the results of in vitro and in vivo bioavailability of hydrocortisone (HC). The three formulations contained oils of different polarity (medium chain triglycerides: MG, isopropyl myristate: IPM and light liquid paraffin: LP), respectively. In vitro permeation was followed through the artificial skin constructs (ASC), while the parameters measured in vivo were erythema index: EI (using instrumental human skin blanching assay), transepidermal water loss (TEWL) and stratum corneum hydration (SCH). The vehicles based on cetearyl glucoside and cetearyl alcohol showed a complex colloidal structure of lamellar liquid-crystalline and lamellar gel-crystalline type, depending on oil polarity. Rheological profile of the vehicle was directly related to the in vitro profile of the HC permeation. In vivo results suggested that the vehicle with MG retarded the HC permeation, whereas less polar IPM and non-polar LP enhanced it. It is suggested that the enhancement is achieved either by a direct interaction with lipid lamellae of the SC or indirectly by improving skin hydration.

There were no adverse effects during in vivo study, which indicates a good safety profile of this alkylpolyglucoside surfactant.