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21.
22.
Automatic Implantable Cardioverter Defibrillator/Permanent Pacemaker Interaction: Loss of Pacemaker Capture Following AICD Discharge 总被引:1,自引:0,他引:1
MARVIN SLEPIAN JOSEPH H. LEVINE LEVI WATKINS Jr. JEFFREY BRINKER THOMAS GUARNIERI 《Pacing and clinical electrophysiology : PACE》1987,10(5):1194-1197
A 78-year-old man treated with amiodarone for recurrent ventricular tachycardia, had sequential placement of a bipolar VVI pacemaker and an automatic implantable cardioverter defibrillator (AICD). During defibrillation threshold testing, there was failure to capture of the pacer in the post-shock period. The time of failure to capture appeared energy-related: the greater the energy delivered, the longer the failure to capture. Careful attention will be necessary in constructing combined AICD/pacemaker units. 相似文献
23.
目的探讨原发性高血压(EH)患者微量白蛋白尿(MCA)与血压及左室重塑的关系.方法 84名EH患者按24h尿微量白蛋白值分为微量白蛋白尿组(MCA组)和正常白蛋白尿组(NMCA组),进行动态血压、心脏超声检测,比较两组动态血压值、左室重量指数(LVMI)及左室重塑的特点.结果 MCA组平均收缩压、平均舒张压、脉压、平均动脉压均高于NMCA组(均P<0.01);MCA组LVMI、左室肥厚与向心性肥厚的发生率均高于NMCA组(均P<0.01),正常构型率低于NMCA组(P=0.01).LVMI与尿微量白蛋白值、平均收缩压、平均舒张压均呈显著的正相关(均P<0.05).结论合并有MCA的EH患者血压较高,LVMI较大,左室肥厚与向心性肥厚的发生率较高.MCA与血压及左室重塑密切相关. 相似文献
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The number of left ventricular assist device (LVAD) implantations is growing as a result of increased waiting periods for cardiac transplantation and the decreased availability of organ donors. Furthermore, the Food and Drug Administration (FDA) has approved permanent LVAD support. After an acute hospitalization, patients with LVADs may need prolonged convalescence in a healthcare facility because they have complex medical needs and are physically disabled. Admission criteria need to be developed as essential patient and nursing competencies need to be defined as a part of a successful LVAD program in an acute rehabilitation center. Acute rehabilitation centers can help patients with LVADs transition to a home setting. 相似文献
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Kun-xi Qian 《Cardiovascular Engineering》2006,6(1):40-42
To investigate the possibility of a long-term applicable left ventricular assist device, a 23 mm outer diameter and 31 g weight implantable aortic valvo-pump was developed. It consists of a rotor and a stator; the rotor has a driven magnets assemble and an impeller, the stator has a motor coil with iron core and a outflow guide vane. The device locates the position of aortic valve, delivers the blood directly from left ventricle to aorta. Neither connecting conduits nor “bypass” circuits are necessary. Therefore, the device has promisingly better antithrombogenicity than other heart pumps. In hemodynamic testing, the pump can produce a blood flow of 7 l/min volume with 50 mmHg pressure increase at 15,000 rpm rotating speed, and at zero flow rate the pump can maintain a diastolic pressure over 80 mmHg at same rotating speed. For further studies the blood compatibility and the durability of the device are of most importance. 相似文献
29.
David B. Burr PhD 《Clinical reviews in bone and mineral metabolism》2006,4(3):155-166
Therapeutic agents used to treat osteoporosis reduce the incidence of vertebral and nonvertebral fractures in osteoporotic
women. The antiremodeling agents, such as the bisphosphonates, prevent bone loss by suppressing the remodeling rate, perhaps
increasing bone volume slightly, and increasing mineralization of the tissue. The anabolic agents, of which rhPTH(1–34) is
the only one approved, accomplish this in a manner that is almost completely the opposite in terms of biological process.
rhPTH(1–34) causes net bone gain by stimulating both modeling and remodeling, by increasing bone volume significantly through
direct bone apposition to trabecular and endocortical surfaces, and by reducing the mean degree of tissue mineralization (a
natural consequence of enhanced remodeling). Each of these treatments maintains or increases bone strength and is similarly
effective at preventing fractures. However, because of their different mode of action, each has different consequences for
bone matrix quality (defined here by microdamage accumulation and by the properties of mineral and collagen) and the mechanical
properties of the tissue. Although bone's composite nature makes it a relatively tough material—more like fiberglass than
glass—the accumulation of damage will nevertheless reduce its residual mechanical properties until the damage is repaired
through remodeling. Agents that suppress remodeling are associated with both microdamage accumulation and increased mineralization.
The biological importance of damage and mineralization to bone's mechanical properties is still a source of debate. 相似文献
30.
Daniel B. Costa Christopher A. Fisher Kenneth B. Miller German A. Pihan David P. Steensma Richard J. Gibbons Douglas R. Higgs 《European journal of haematology》2006,76(5):432-435
Abstract: We describe a patient with acquired alpha-thalassemia myelodysplastic syndrome (ATMDS). A previously healthy 66-year-old man presented with hemoglobin of 9.3 g/dL, mean corpuscular volume 59 fL, and a bone marrow aspirate with increased erythroid precursors and hypolobulated megakaryocytes. Hemoglobin H inclusions were seen in most red cells after 1% brilliant cresyl blue supravital stain of the peripheral blood. At the molecular level, we identified of a novel mutation in the most 3' exon of the ATRX gene ( C GA→ T GA substitution in codon 2407) resulting in a premature termination codon (p.R2407X). This case provides further evidence for a link between ATRX mutations and ATMDS, and suggests a possible role for the conserved Q-box element in ATRX function. 相似文献