全文获取类型
收费全文 | 15898篇 |
免费 | 2096篇 |
国内免费 | 455篇 |
专业分类
耳鼻咽喉 | 221篇 |
儿科学 | 362篇 |
妇产科学 | 138篇 |
基础医学 | 1011篇 |
口腔科学 | 256篇 |
临床医学 | 1108篇 |
内科学 | 1218篇 |
皮肤病学 | 622篇 |
神经病学 | 350篇 |
特种医学 | 2255篇 |
外国民族医学 | 15篇 |
外科学 | 1532篇 |
综合类 | 1856篇 |
现状与发展 | 1篇 |
预防医学 | 1208篇 |
眼科学 | 261篇 |
药学 | 1057篇 |
4篇 | |
中国医学 | 631篇 |
肿瘤学 | 4343篇 |
出版年
2024年 | 28篇 |
2023年 | 244篇 |
2022年 | 412篇 |
2021年 | 669篇 |
2020年 | 542篇 |
2019年 | 578篇 |
2018年 | 619篇 |
2017年 | 602篇 |
2016年 | 749篇 |
2015年 | 778篇 |
2014年 | 1215篇 |
2013年 | 1517篇 |
2012年 | 1039篇 |
2011年 | 1068篇 |
2010年 | 774篇 |
2009年 | 676篇 |
2008年 | 695篇 |
2007年 | 669篇 |
2006年 | 636篇 |
2005年 | 583篇 |
2004年 | 494篇 |
2003年 | 459篇 |
2002年 | 376篇 |
2001年 | 343篇 |
2000年 | 294篇 |
1999年 | 244篇 |
1998年 | 223篇 |
1997年 | 223篇 |
1996年 | 223篇 |
1995年 | 152篇 |
1994年 | 128篇 |
1993年 | 119篇 |
1992年 | 101篇 |
1991年 | 122篇 |
1990年 | 96篇 |
1989年 | 96篇 |
1988年 | 85篇 |
1987年 | 74篇 |
1986年 | 69篇 |
1985年 | 89篇 |
1984年 | 65篇 |
1983年 | 61篇 |
1982年 | 47篇 |
1981年 | 37篇 |
1980年 | 44篇 |
1979年 | 33篇 |
1978年 | 13篇 |
1977年 | 15篇 |
1976年 | 16篇 |
1975年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
41.
Moshe Stein N. Haim Abraham Kuten Yafa Doron Yehudi T. Ben Arieh Yoram Cohen 《Journal of surgical oncology》1992,51(4):270-273
Thirty-three patients with primary gastrointestinal lymphoma (GIL) followed at Ankara University Medical School have been evaluated. The most frequent locations of the disease are the small intestine (48.4%) and the stomach (39.3%). The intermediate and high grade lymphomas constitute 84.8% of the cases. The mean age of the patients with small intestinal lymphoma is 28.7 years and 47.1 years for those with gastric lymphoma. The patients treated with surgery and chemotherapy (S+CT) have a longer survival than those treated with chemotherapy (CT) alone. In conclusion: 1) Small intestinal lymphoma occurs more frequently than gastric lymphoma in our study. 2) The median age of the Turkish patients with primary GIL is approximately 10 years less than those in the Western countries. 3) The therapeutic results of S+CT are superior to those of CT in the early stages of the disease. 相似文献
42.
ThedynamicdistributionofnitricoxidesynthaseinthesmallintestineofmicewithintestinalradiationsicknessWeiLichun(魏丽春);GuoYao(郭鹞)(... 相似文献
43.
Localized proton spectroscopy of inoperable brain gliomas. Response to radiation therapy 总被引:3,自引:0,他引:3
M. A. A. M. Heesters R. L. Kamman E. L. Mooyaart K. G. Go 《Journal of neuro-oncology》1993,17(1):27-35
Within vivo 1H-MRS resonances of several metabolites were simultaneously measured in cerebral gliomas and adjacent normal brain. 15 patients with inoperable brain gliomas all histologically verified were monitored with 1H-MRS and MRI before and after radiotherapy. 11 patients were evaluable. 1H-MRS technique evolved from single volume measurements to one dimensional and two dimensional 1H spectroscopic imaging. In all patients N-acetyl-aspartate signals were decreased in tumour areas compared to the normal brain hemisphere. No recovery was seen after radiotherapy. Choline signals were increased in tumour margins of high grade gliomas and more diffusely in low grade gliomas. In 5 patients the choline resonance decreased after radiotherapy, accompanied by a shrinkage of tumour diameter on MRI. Lactate signals were present in high grade and unspecified astrocytomas and absent in most low grade gliomas. In 3 patients the lactate signal disappeared after radiotherapy. These observations indicate the feasibility of 1H-MRS in monitoring metabolic responses on radiotherapy of brain gliomas. 相似文献
44.
Katsumi Harasawa Osamu Kemmotsu Takahisa Mayumi Yoshiteru Kawano 《Journal of clinical monitoring and computing》1997,13(1):19-24
Objective. Tympanic temperature can be obtained instantaneously using an infrared emission detection (IRED) thermometer. Its accuracy has been documented in a variety of clinical settings, but its performance at low body temperatures is still unknown. In this study we evaluated its performance during coronary artery revascularization surgery in which mild hypothermic cardiopulmonary bypass (CPB) was used. Methods. Thirty adult patients undergoing coronary artery bypass graft surgery were enrolled in the study. Tympanic temperature obtained using IRED thermometry (Tt1) was compared with core temperatures from the esophagus (Te), and venous blood of CPB (Tv) before, during, and after CPB. We also measured tympanic temperature using a thermocouple probe (Tt2) in 16 of the 30 patients in order to study the agreement between the two methods. Values for correlation coefficients and limits of agreement were computed to assess the degree of agreement among the temperatures obtained. Results. The highest agreement with Tv during CPB was obtained from Tt1 (r = 0.94, 0.41 ± 1.73, limits of agreement) and from Te (0.91, 0.36 ± 2.46). Tt1 also showed good agreement with Tt2 during surgery. Conclusions. Infrared tympanic thermometry is a reliable, alternative method to measure tympanic temperature and may be useful to assess core temperature in both normothermic and mild hypothermic conditions. 相似文献
45.
以肝、脾组织中过氧化脂质(LPO)含量及谷胱甘肽过氧化物酶(GSHL-Px)活性为指标探讨硒的辐射防护效应。实验结果表明:BALB/C纯系雄性小鼠经3Gy ~(60)Co γ射线照射后3天,肝、脾组织LPO生成量比未照射者均显著增多,而GSH-Px活性却都显著降低;但于照射前连续7天每日经口灌胃亚硒酸钠溶液0.2ml(含硒12.5μg)的实验组动物,肝、脾组织LPO含量均明显少于照射对照组,而GSH-Px活性都显著高于照射对照组,结果提示,通过降低LPO含量和增加GSH-Px活性,硒对小鼠可能有辐射防护作用。 相似文献
46.
全身(全淋巴)照射后100例医源性急性放射病的临床分析 总被引:1,自引:1,他引:0
在造血干细胞移植治疗肿瘤过程中用全身照射(TBI)或全淋巴照射(TLI)预处理,研究受照不同剂量患者发生医源性急性放射病严重程度,治疗方法和造血恢复及相关合并症。方法100例患者(白血病91例,其他肿瘤9例)接受500~1000cGyTBI或TLI和超大剂量化疗作预处理。结果均发生医源性急性放射病,白细胞降至(0~0.15)×109/L,骨髓空虚,合并各种感染和出血。经造血干细胞移植,抗感染,应用GM-CSF或G-CSF积极支持治疗及保护隔离措施,92例造血恢复,8例死于不同感染和出血。结论造血干细胞的移植起主要治疗作用,不同造血因子用于治疗急性放射病,可能是一种有希望的方法 相似文献
47.
T. KRANTZ F. SZTUK F. SWIATEK J. JACOBSEN N. H. SECHER 《Acta anaesthesiologica Scandinavica》1997,41(6):719-724
Background: We evaluated the ability of the standards issued by the Danish Society of Anaesthesiologists to reflect a blood loss.
Methods: In 9 pigs bled (0–24 ml kg-1 ) and retransfused (to 28 ml kg-1 ) during halothane anaesthesia, central cardiovascular, thoracic electrical impedance (TI), oxygen, acid-base and temperature variables were recorded.
Results: With the recommendation for minor surgery (mean arterial pressure (MAP) and heart rate (HR)), the correlation to the blood loss was 0.74 ( P < 0.001) and with that for major surgery (MAP, HR, central venous pressure (CVP) and rectal temperature (Tempr )) it was 0.79 ( P < 0.001). With the recommendation for extensive surgery (MAP, HR, CVP, pulmonary artery catheter variables and the central-peripheral temperature difference (ΔTempr-t )), the correlation was 0.84 ( P < 0.001). Non-invasive monitoring (MAP, HR, ΔTempr-t TI and near-infrared spectroscopy of the brain (Sinvos O2 )) was only slightly better than basal monitoring (r=0.76, P < 0.001). However, adding arterial base excess (BE), TI and peripheral temperature (Tempt ) to the recommendation for major surgery resulted in a correlation of 0.87 ( P < 0.001), while adding BE and TI to the recommendation for extensive surgery raised correlation to only 0.88 ( P < 0.001).
Conclusion: When the recommendations were followed the correlation to the blood loss ranged from 0.74–0.84. However, with the recording of MAP, HR, CVP, ΔTempr-t, BE and TI a correlation of 0.87 was achieved, indicating that a pulmonary artery catheter may not be in need for patients undergoing surgical procedures with expected haemorrhage. 相似文献
Methods: In 9 pigs bled (0–24 ml kg
Results: With the recommendation for minor surgery (mean arterial pressure (MAP) and heart rate (HR)), the correlation to the blood loss was 0.74 ( P < 0.001) and with that for major surgery (MAP, HR, central venous pressure (CVP) and rectal temperature (Temp
Conclusion: When the recommendations were followed the correlation to the blood loss ranged from 0.74–0.84. However, with the recording of MAP, HR, CVP, ΔTemp
48.
简述了淋巴细胞亚群微核检测方法、淋巴细胞亚群自发微核率和影响因素,以及关于电脑射效应的研究现状,为微核法用于辐射生物剂的未来发展提供了有益信息。 相似文献
49.
麦胚提取物对辐射损伤修复的实验研究 总被引:2,自引:1,他引:1
目的 研究麦胚提取物对小鼠辐射损伤修复的调节和保护作用。方法 采用辐射前或辐射同时饲喂一定量的麦胚提取物,观察小鼠经X射线一次性全身照射后的临床症状、30d存活率、骨髓微核率、外周血白细胞总数在不同时间的变化。结果 与对照组(单纯照射)比较,饲喂麦胚提取物可使小鼠的头面部皮肤、小肠黏膜、肾脏损伤症状得到明显改善;30d存活率为86.17%(P<0.01),提高存活率41.79%,保护系数为1.72;骨髓微核率4.62‰;比对照组(12.14‰)降低(P<0.01);外周血白细胞总数在7,13,20,30d均显回升(P<0.05,P<0.01,P<0.01,P<0.01)。结论 麦胚提取物对小鼠辐射损伤修复有一定程度的调节和保护作用,对于辅助肿瘤放射治疗具有重要意义。 相似文献
50.
目的观察一例大剂量全身极不均匀照射急性放射损伤患者数处局部病理改变。方法病理常规切片染色,光镜检查。结果吸收剂量右下肢为3738Gy,左手掌为830Gy,于照射后第8天行右下肢、左前臂截肢术。右手、左膝照射剂量相对较小但难以准确估计,红斑、水肿、水疱、溃疡出现相对较晚,于第55天行右手指、左膝清创植皮术。镜下:右小腿局部皮肤和皮肤附属器官、皮下组织和骨胳肌广泛地坏死和弥漫性出血,但真皮中的立毛肌尚存;左手指、手掌皮肤表皮细胞空泡变性、坏死,并形成大小不一的囊泡,致使表皮与真皮分离,真皮弥漫性出血、中性粒细胞浸润,汗腺上皮细胞变性、坏死,皮下组织内弥漫性出血,少数脂肪细胞坏死。胫骨、腓骨上端和股骨、桡骨、尺骨下端处骨髓腔内造血组织各系细胞均消失。左膝、右手拇指、食指、中指皮肤示急性放射性溃疡。结论大剂量照射导致的急性放射损伤造成大面积、深达肌肉的软组织坏死及骨髓造血细胞消失。 相似文献