左乙拉西坦治疗婴儿痉挛症的疗效

目的 探讨左乙拉西坦(LEV)对婴儿痉挛症(IS)的疗效和安全性.方法 对武汉市4家医院进行多中心联合研究.采用前瞻性研究,制定严格研究方案,统一纳入标准和排除标准,选择完成3个月以上疗程的IS患儿13例.男10例,女3例;年龄2.5～24个月.LEV起始剂量10 mg/(kg·d),每周添加10 mg/(kg·d)至最小有效剂量;治疗期间检测肝、肾功能及血常规,每2～4周门诊或电话随访1次,密切观察临床疗效及不良事件,应用3个月以上评价临床疗效.结果完全缓解4例(30.8%),有效5例(38.5%),无效4例(30.8%);LEV起效剂量(17.772±9.511)mg/(kg·d),完全缓解剂量(20.938±6.084)mg/(kg·d);起效时间(1.50±0.535)周,完全缓解时间(6.750±6.602)周.4例出现不良反应(30.8%),食欲下降、嗜睡各2例(各15.4%),未见严重致死性不良反应,治疗期间未见肝、肾功能及血常规异常改变.结论 LEV治疗IS具有良好疗效及安全性.     

穴位注射氟哌啶预防输卵管结扎术中牵拉反应200例

穴位注射氟哌啶预防输卵管结扎术中牵拉反应２００例王海波，李萍我们在局部麻醉的基础上，结合内关穴注射氟哌陡，以预防输卵管结扎术中牵拉反应及术中术后患者的恶心、呕吐症状，取得了满意效果。现报告如下。临床资料１９９５年２月～１９９５年１２月，对在我科门诊准...     

西瓜霜辅助激光治疗宫颈糜烂113例临床观察

西瓜霜辅助激光治疗宫颈糜烂１１３例临床观察上海长征医院（上海２００００３）隋龙，杨云纺，许凤娣，蔡庆如，辜荣飞，方爱华上海嘉定区中心医院陆璇１９９２年６月～１９９４年１２月，我们应用西瓜霜辅助ＣＯ２激光治疗宫颈糜烂，效果较好，现报告如下。一般资料２１...     

小儿泻速停冲剂治疗秋季腹泻101例

小儿泻速停冲剂治疗秋季腹泻１０１例福建省三明市第三医院儿科（福建３６５００１）潘用再小儿泻速停冲剂（简称泻速停）是治疗小儿腹泻病新药，对各种小儿腹泻具有快速止泻作用。为进一步验证该药对小儿秋季轮状病毒性腹泻的疗效，我们于１９９３年１０～１２月使用该药...     

Failure of calcitriol treatment in a patient with malignant osteopetrosis

In an attempt to stimulate bone resportion, a 10-week-old infant with malignant infantile osteopetrosis was treated with high doses of calcitriol, a potent bone resorption stimulatory agent, combined with a low calcium diet to prevent hypercalcaemia. Although calcitriol administration was initiated at this very young age, our patient did not show any clinical, radiological, or histological improvement. Despite reports of positive results of this treatment in the literature, our patient did not reveal any signs of bone resorption. She eventually died from the complications of osteopetrosis at the age of 6 months after 88 days of therapy.     

Dietary modifications versus dicyclomine hydrochloride in the treatment of severe infantile colics

This study examined 120 infants, aged 3–12 weeks, with severe colics and compared the results of a specific hypoallergenic diet (group A) with those of pharmacological treatment (group B). Non-breastfed group A infants received soy milk and if unresponsive, hydrolyzed milk formulas; mothers of breast-fed infants received a diet without cow's milk, eggs or fish. Breast-fed and non-breast-fed group B infants received dicyclomine hydrochloride 3 mg/kg/day. Results, based on quantitative measurements of crying. indicated that in breast-fed infants there was no significant improvement between group A (62.5%) and group B (66.6%) infants. Among formula-fed infants, comparison of positive results using soy milk (65.9%) with positive results using dicyclomine (53.3%) was not significant; positive results using soy milk and hydrolyzed milk formulas in non-responders to soy milk, provided an improvement in 95.4% of cases. Pharmacological treatment provided an improvement in 53.3%) of cases. The diffcrence was significant ( p <0.01).     

Granuloma gluteale infantum

Granuloma gluteale infantum is an uncommon disorder, the pathogenesis of which remains unclear. Occlusion is a common factor and irritant napkin dermatitis is a frequent association. A six month old female infant with mild napkin dermatitis treated only with a dusting powder is presented.     

Effect of Shenmai Injection(参麦注射液) on Cardiac Function and Cellular Immunity of Patients with Infantile Viral Myocarditis

ＥｆｆｅｃｔｏｆＳｈｅｎｍａｉＩｎｊｅｃｔｉｏｎｏｎＣａｒｄｉａｃＦｕｎｃｔｉｏｎａｎｄＣｅｌｌｕｌａｒＩｍｍｕｎｉｔｙｏｆＰａｔｉｅｎｔｓｗｉｔｈＩｎｆａｎｔｉｌｅＶｉｒａｌＭｙｏｃａｒｄｉｔｉｓ￥ＬＩＹａ－ｒｕｉ（ＰｅｄｉａｔｒｉｃｓＦａｃｕｌｔ...