自体颗粒脂肪在眼睑凹陷畸形中的应用

目的 探讨对眼睑凹陷畸形患者采用自体颗粒脂肪注射移植术治疗的临床效果.方法 选择2018年11月至2019年11月期间我院的眼睑凹陷畸形患者65例,所有患者均采用自体颗粒脂肪注射移植术进行眼睑凹陷治疗,治疗后对患者进行为期一年的随访工作,分别观察其治疗效果,并对患者术后并发症发生情况以及治疗满意情况进行统计.结果 所有...     

椎间孔镜下改良环锯技术部分切除增生上关节突治疗腰神经根卡压综合征的效果

目的 评估椎间孔镜下改良环锯技术部分切除增生上关节突(superior articular process,SAP),治疗SAP增生引起的腰神经卡压综合征(lumbar nerve root entrapment syndrome,LNRES)的效果.方法 选择2015-04至2019-07医院收治的LNRES患者10...     

加替沙星阳离子脂质体的制备及性质测定

 目的制备加替沙星阳离子脂质体并测定其粒径、Zeta电位、包封率。方法采用薄膜分散法制备加替沙星阳离子脂质体,正交实验筛选处方,葡聚糖凝胶法测定其包封率,COULTERLS粒径分析仪测定粒径,COULTER DELSA 440SXξ电位仪测定Zeta电位,采用改良的Fraze扩散池和离体角膜测定加替沙星阳离子脂质体的体外释放,并比较普通滴眼剂、中性脂质体和阳离子脂质体角膜透过系数。结果采用薄膜分散法制备的加替沙星阳离子脂质体外观良好,包封率为69.5%,平均粒径为163nm,Zeta电位为44.7mV,阳离子脂质体的角膜透过系数分别是普通滴眼剂和中性脂质体的5.44和1.19倍。结论自制的加替沙星阳离子脂质体包封率较高,粒径较小,粒度分布较窄,脂质体囊泡荷正电,离体角膜透过性良好,较可能成为一种理想的眼用制剂。     

大蒜素脂质体的研制及其质量评价

目的:对大蒜素脂质体的处方和制备工艺进行研究,并评价其质量.方法:采用反相蒸发法制备了大蒜素脂质体,并对制剂的形态学、包封率、粒径分布、稳定性等性质进行了研究.结果:本研究制备的大蒜素脂质体包封率为87.19%;透射电子显微镜下观察脂质体为粒径均匀的球状或近球状的囊泡,平均粒径为114.8nm,＜183nm的粒子占90%.结论:大蒜素脂质体包封率高,质量稳定,重现性好.     

颈神经在椎间孔及脊神经沟处受嵌压致颈椎病的关系比较

目的　比较颈神经在椎间孔及脊神经沟处受嵌压的出现率及严重程度。方法　取 6 0具成年尸体 (男 2 8,女 32 ) ,通过对颈椎间孔及其脊神经根的外径以及对脊神经沟外口宽度及其沟内段脊神经前支横径的测量 ,得出颈神经前支横径 /脊神经沟宽度和颈神经根外径 /椎间孔大小的均值 ,得出比值大于或等于 1的出现率 ,并分别进行统计学处理。结果　颈神经在椎间孔处受压的出现率 ( 2 4.6 %)明显高于脊神经沟处 ( 6 .3%) ( P <0 .0 1)。结论　颈神经在颈椎间孔和脊神经沟处均可受累 ,颈神经在椎间孔处受累的严重性明显大于在脊神经沟处。临床诊治颈椎病在充分考虑椎间孔处神经受累的同时 ,也不可忽视颈椎脊神经沟处神经受累的可能性。     

Ultrasonography in patients with ulnar neuropathy at the elbow: Comparison of cross‐sectional area and swelling ratio with electrophysiological severity

The aim of this study was to determine the diagnostic value of ultrasonographic measurements in ulnar neuropathy at the elbow (UNE) and to assess the relationship between the measurements and the electrophysiological severity. The largest anteroposterior diameter (LAPD) and cross‐sectional area (CSA) measurements of the ulnar nerve were noted at multiple levels along the arm, and the distal‐to‐proximal ratios were calculated. Almost all of the measurements and swelling ratios between patients and controls showed statistically significant differences. The largest CSA, distal/largest CSA ratio, CSA at the epicondyle, and proximal LAPD had larger areas under the curve than other measurements. The sensitivity and specificity in diagnosing UNE were 95% and 71% for the largest CSA, 83% and 85% for the distal/largest CSA ratio, 83% and 81% for the CSA at the epicondyle, and 93% and 43% for the proximal LAPD, respectively. There was a statistically significant correlation between the electrophysiological severity scale score (ESSS) and the largest CSA, the CSA at the epicondyle and 2 cm proximal to the epicondyle, and the LAPD at the level of the epicondyle (P < 0.05). None of the swelling ratios showed a significant correlation with the ESSS. The largest CSA measurement is the most valuable ultrasonographic measurement both for diagnosis and determining the severity of UNE. Muscle Nerve, 2010     

Development and clinical significance of the musculus dorsoepitrochlearis in men

Musculus dorsoepitrochlearis is a typical muscle variation, which, if in full extent, is represented by the muscular or fibromuscular slip detached from the anteroinferior border of the musculus latissimus dorsi. It passes over the axilla under the axillary fascia crossing the medial side of the brachial plexus and continues as a septum intermusculare mediale brachii distally to the medial epicondyle of humerus. Its full extent is rarely developed—the connection into the intermuscular septum being mostly absent. Muscular slips from the musculus latissimus then insert on various structures in the axilla, often on the crest of greater tubercle of humerus or into the musculus pectoralis major (this variation is known as the axillary arch of Langer) or to other neighboring structures (coracoid process, fasciae of muscles). In our observations, 209 patients with traumatic lesions of the brachial plexus underwent surgical procedure. The presence of the musculus dorsoepitrochlearis has been observed. It was found in the form of various slips from the musculus latissimus dorsi in 4 patients. In 3 of those 4 patients, the innervation was derived from the nervus thoracodorsalis. We also presented 2 case reports of patients with clinical symptoms caused by compression of nerves in the axilla by the dorsoepitrochlear strip. Clin. Anat. 22:481–488, 2009. © 2009 Wiley‐Liss, Inc.