双器械吻合技术在低位直肠癌保肛手术中的应用

目的探讨双器械吻合技术在低位直肠癌保肛手术中的适应证和可行性.方法回顾性分析该院7a间利用双器械吻合技术治疗直肠癌60例的临床资料.结果效果良好,术后病理报告上下缘无癌细胞;无手术死亡,吻合口漏1例(1.67%),吻合口狭窄2例(3.33%),全部病例8个月后大便功能正常.结论双器械吻合技术可扩大Dixon手术适合证范围,而且提高了患者生存质量.     

《生物化学》课程改革的实践与思考

探讨了在生物化学课程教学中,通过培养学生的学习兴趣,优化和更新教学内容、综合使用教学方法和手段来提高教学质量和学生综合素质及能力的经验.     

以排精为首发症状的狂犬病1例

狂犬病是一种由狂犬病毒引起的人畜共患传染病，一旦发病，死亡率几乎达100％，是迄今为止人类病死率最高的急性传染病。狂犬病首发症状多不典型，现报道我科收治的以排精为首发症状的狂犬病1例，以引起临床医生重视。     

子宫肌瘤大鼠模型制备方法之比较

目的比较两种子宫肌瘤大鼠模型的制备方法。方法采用单用己烯雌酚肌注（单模法）和己烯雌酚与黄体酮共同肌注（双模法）的方法制备子宫肌瘤大鼠模型。结果两种方法均能制备子宫肌瘤大鼠模型，子宫肌瘤大鼠出现血清性激素水平升高、免疫功能低下及肌细胞高度增生活跃的病理状态，综合评价双模法优于单模法。结论两种方法均能成功制备子宫肌瘤大鼠模型。     

中国首个大型医院品牌营销研究

通过对全国11个中心城市的20家大型三甲医院的3924名病人及1815名员工进行随机抽样调查及对406名医务工作者进行一对一深度访谈,对中国大型医院品牌营销现状进行研究探讨,得出如下初步结论,供医院管理者参考:医院以技术品牌为主;员工品牌意识薄弱,服务品牌有待加强;医院品牌区域性强,外地病人多为自费;病人支付能力参差不齐;医院品牌营销尚在起步阶段.     

卡诺定理的一种直接证明方法

目前普通物理学、热力学及热统教材中,证明卡诺定理多采用反证法。本文给出了由热力学第一定律 和热力学第二定律直接证明卡诺定理的一种方法。     

重点高中新生心理健康调查与分析

目的通过对云南省省属重点中学住校新生的心理健康状况进行调查研究，有针对性地制定心理健康教育工作方案。方法用周步成的心理健康诊断测验方法，对来自全省的512名住校中学生进行调查。结果有21．9％的学生存在不同程度的心理问题；男生问题率是17．6％，女生问题率是27．7％，在学习焦虑、自责倾向、恐怖倾向和冲动倾向方面性别差异显；汉族学生心理健康水平比少数民族学生略高；昆明市市区与昆明市周边县、昆明市周边县与地州县市的学生之间各项指标均无显差异；昆明市市区学生在学习焦虑、对人焦虑、自责倾向和过敏倾向上均显好于地州县市学生；父母化程度高低对子女心理健康影响较大，母亲化差异对子女心理健康的影响高于父亲。结论重点中学高一住校生有一定比例的人存在心理健康问题，性别、生源及父母的化程度影响学生的心理健康。     

丙二醇用量对湿疹喷雾剂透皮作用的影响

目的为提高湿疹喷雾剂对皮肤的渗透能力，增强疗效。方法采用定制的改良Franz扩散池，大鼠腹皮作透皮试验，一阶导数光谱法测定本制剂中黄芩苷的含量，考察不同浓度的丙二醇对黄芩苷经皮渗透的影响。结果各种浓度的丙二醇累积渗透百分率达5％所需时间T5由短(快)到长(慢)顺序为8．0％、7．0％、5．0％、6．0％、15．0％、10．0％；经皮渗透5小时内累积渗透百分率Q5h由大到小依次为7．0％、6．0％、5．0％、8．0％、15.0％、10．0％。结论丙二醇在湿疹喷雾剂中促渗作用最佳浓度为体积分数的7．0％-8.0％。     

32464例病案首页数据质量分析报告

对32464份病历病案首页缺陷进行统计分析,结果显示,病案首页基本缺陷的构成比最高,其它依次为缺主任签名,缺术前诊断与术后诊断符合情况,缺手术情况等等,并就导致缺陷的原因进行探索和提出相应的对策。     

A similar high level of immunoglobulin A and immunoglobulin G class milk antibodies and increment of local lymphoid tissue on the duodenal mucosa in subjects with cow's milk allergy and recurrent abdominal pains

In previous studies, we have reported endoscopic and histological alterations locally on the gastrointestinal (GI) tract associated with a gastrointestinal type of cow's milk allergy. In this study, we sought to further characterize endoscopic, and immunological findings in these children. We also hypothesized that the same type of immune responses might also be found in children with unexplained and recurrent abdominal pains. We did a gastroduodenoscopy for persistent GI symptoms, examined the mucosal histology of the small intestine and measured the antibodies to whole cow's milk and its fractions with an enzyme‐linked immunosorbent assay (ELISA) in a consecutive series of 22 subjects with untreated and 14 with treated cow's milk allergy (CMA) and 44 with recurrent abdominal pains (RAP). The immunological findings of the study subjects were compared with 54 controls. Lymphonodular hyperplasia (LNH) of the duodenum was the main endoscopic finding in 11 subjects (50%) with untreated and 5 (36%) with treated CMA. It was also found in 6 of 44 subjects with RAP. Compared with the controls, the patients with CMA showed significantly higher levels of IgA class antibodies to whole milk (p = 0.003) and βLG (p < 0.0001). Of the IgG class antibodies to βLG (p = 0.032), BSA (p < 0.0001) and αCAS (p < 0.0001) were significantly higher. The patients with LNH of the duodenal bulb as the main endoscopic finding showed significantly higher values of IgG class antibodies to βLG (p = 0.01) and αCAS (p = 0.005). Interestingly, the patients examined for RAP showed a similar increment in the pattern of whole milk and specific milk protein antibodies as the CMA children. In conclusion this study showed that gastrointestinal CMA beyond infancy is significantly associated with high levels of IgG and IgA class antibodies to milk and its fractions. As high levels of these antibodies and LNH of the duodenal bulb were also found in subjects with RAP, the study further suggests that gastrointestinal CMA might be one major reason for RAP.