应用经阴道彩色多普勒对健康育龄妇女子宫卵巢动脉血流状况的研究

目的 研究育龄妇女子宫、卵巢动脉血流变化规律。方法 应用经阴道彩色多普勒对４６０例妇女子宫、卵巢动脉血流在不同月经周期进行搏动指数（ＰＩ）、阻力指数（ＲＩ）检测。结果 血流参数在四个周期间有非常显著性差异（Ｐ〈０．０１）,同时功能侧子宫动脉与卵巢动脉阻抗参数也有差异（Ｐ〈０．０５）。结论 通过检测子宫、卵巢动脉血流有助于对妇科疾患的诊断提供帮助。     

英汉颜色词差异浅探

英、汉语分属两种不同的语系 ,受语言与文化特殊性的影响 ,人们对色彩的感受和赋予颜色词的意义也各不相同。翻译时 ,不可望文生义 ,“对号入座” ,必须在充分了解中西方文化差异的基础上 ,准确把握颜色词所处的语境 ,力求做到信、达、雅     

复合先心病的彩色多普勒超声诊断

目的 :应用彩色多普勒超声心动图 (CDE)诊断 4例复合型先心病。方法 :回顾分析经CDE检查及手术证实的患者。结果 :3例房间间隔缺损分别合并部分肺静脉异位引流、三房心、二尖瓣脱垂及三尖瓣裂孔 ;1例室间隔缺损合并左上腔。除左上腔被漏诊外 ,其余都与手术符合。结论 :超声对复合型先心病具有无创性、可重复性、诊断率高的重要价值。     

高血压病及糖尿病患者肾血流的彩色多普勒速度能量图评价及其影响因素分析

目的：本研究旨在观察高血压病（ＥＨ）及糖尿病（ＤＭ）患者肾动脉血流的彩色多普勒速度能量图（ＣＣＤ）变化并探讨其影响因素。方法：以正常对照组及ＥＨ组,ＤＭ组为研究对象,每组各６０例,均为男３０例,女３０例,对照组年龄３７～７５岁,ＥＨ组４０～７７岁,ＭＤ组４１～７３组,采用ＡＣＵＳＯＮ公司生产的ＡＳＰＥＮ彩色多普勒超声显像仪,探头频率４～２ＭＨＺ及３．５ＭＨＺ,应用ＣＣＤ测量肾动脉主干最大血流速度（     

彩色多普勒超声对甲状腺肿块的诊断价值

目的 探讨彩色多普勒超声（ＣＤＦＩ）对甲状腺肿块的诊断价值。方法 采用彩色多普勒超声观察４５例患者５９个甲状腺肿块周边部及内部的彩色血流和异常高速的血流信号。结果 ①良性甲状腺肿块周边部及内部常显示稀少的彩色血流信号（７７．４％）,而恶性甲状腺肿块周边部及中央部多显示丰富的彩色血流流信号（８２．１％）。②恶性甲状腺肿块的异常高速血流（〉７０ｃｍ／ｓ）检出率与良性甲状腺肿块差异无显著性（Ｐ〈０．０５     

人体牙齿颜色测量系统口内活体牙测量重复性的研究

对人体牙齿颜色测量系统的重复性进行研究。方法：采用ＣＩＥ１９７６Ｌ＾＊ａ＾＊ｂ＾＊色度参数对７名自愿者上中切牙进行测量,通过比较不同时间、不同损伤者测量结果差异,计算、比较不同时间测量色差偏差的大小,研究人体牙齿颜色测量系统的重复性。结果：本实验所测人体牙齿颜色系统在不同时间测量结果的色差偏差为１．０２６个单位,且不同时间比较该色差值无显著性差异;不同时间内测量指标比较除ａ＾＊以外,Ｌ＾＊,ｂ＾＊     

Effects of intravenous nitroglycerin combined with dopamine on intracranial pressure and cerebral arteriovenous oxygen difference in patients with acute subarachnoid haemorrhage

Summary The effects of intravenous nitroglycerin (NTG) combined with dopamine on intracranial pressure (ICP) and cerebral arteriovenous oxygen difference (AVDO₂) were studied in 11 patients with acute subarachnoid haemorrhage (SAH). The study was performed on Days 1 to 3 of SAH after aneurysmal clipping. Treatment consisted of an intravenous drip infusion of NTG in increasing incremental doses of 0.5, 1.0, 1.5, 2.0, and 2.5 g/kg/min at one-hour intervals. Dopamine (5 to 10 g/kg/min) was also given concurrently to maintain systemic blood pressure. ICP values before NTG administration ranged from 7 to 24 mmHg (mean, 11.91±5.30 mmHg). ICP began to increase immediately after the adminisration of NTG 0.5 g/kg/min and peaked at 14.64±5.93 mmHg 10 minutes after onset of infusion. Thereafter, ICP gradually returned to pretreatment levels. Increasing the dose of NTG failed to induce further significant rises in ICP. Mean AVDO₂ before NTG administration was 4.69±0.62 ml/dl. This parameter showed no significant change during NTG infusion, although cerebral perfusion pressure decreased to between 75% to 94% of the control value after NTG administration. These results indicate that continuous NTG infusion combined with dopamine does not have adverse effects on ICP (the ICP increase is minimal and transient) and may even have beneficial effects on CBF in patients with acute SAH.     

Prospective feasibility study of a mindfulness-based program for breast cancer patients in the southeastern US

BackgroundMindfulness interventions can improve psychological distress and quality of life (QoL) in cancer survivors. Few mindfulness programs for cancer recovery exist in Southeastern U.S. The primary objective of this study was to assess the feasibility of a modified mindfulness-based stress reduction (MBSR) program for breast cancer patients in Birmingham, Alabama. The secondary objective was to explore potential program effects on mindfulness skills and QoL.MethodsThis study was a prospective, quasi-experimental feasibility study conducted over 10 months at a university hospital. Feasibility was achieved if 80% of eligible patients screened enrolled in the study and 70% of enrolled patients attended all 8 program sessions. Effectiveness was estimated by changes in mindfulness and QoL indicators measured with validated scales administered at 3 time points and assessed with a non-parametric Friedman test. Sessions included meditation, yoga, and an attention practice called body scan. There were 3 groups of 2–5 patients.ResultsThe sample totaled 12 patients. Forty-four percent (12/27) of eligible patients enrolled in the study, and two out of 12 enrolled patients completed 8 program sessions, resulting in 16.7% (2/12) retention. However, more than half (66.7%) of participants completed at least 7 sessions. Between baseline and 8-week follow-up, patients demonstrated statistically significant improvements in distress, general wellbeing, and fatigue-related QoL.ConclusionsFeasibility objectives were not achieved. However, a majority of participants (66.7%) completed 7 of 8 program sessions. Program effects were promising for distress, fatigue, and wellbeing. Results warrant further research on MBSR-like programs for breast cancer patients in Alabama.     

鼻咽癌中与已知基因同源的差异表达cDNA序列

采用新近发展的ｃＤＮＡ代表性差异分析法筛选鼻咽癌中不表达的或表达降低的ｃＤＮＡ序列。结果显示：有９个与已知基因高度同源的ｃＤＮＡ序列。通过对这些已知基因的结构和功能分析,发现有与细胞骨架成分相关的基因：αａｃｔｉｎｉｎ,ｅｚｒｉｎ和细胞角蛋白１３;直接与瘤基因和抑瘤基因相互作用的基因：鲨烯合成酶和ＴＲＩＰ１基因;直接参与ＤＮＡ合成以及调控基因转录和翻译的基因：ＴＡＦⅡ６８和组蛋白Ｈ１０;另外还有人类补体因子Ｂ及类转运ＲＮＡ合成酶的基因。这些基因大多具有相当于抑瘤基因的功能。从而进一步说明鼻咽癌的发生是多基因相互作用的结果。     

Relations of hippocampal volume and dentate gyrus width to gonadal hormone levels in male and female meadow voles

The present study examined hippocampal volume and dentate gyrus width and their relations to gonadal hormone levels in adult male and female meadow voles, Microtus pennsylvanicus. Females were split into High and Low Estradiol groups based on the median estradiol level. Males were similarly split into High and Low Testosterone groups. Contrary to previous reports in wild meadow voles, there was no evidence of an overall sex difference in hippocampal volume. However, when male-female comparisons were limited to High Testosterone males and Low Estradiol females a significant sex difference in hippocampal volume favouring males did emerge. Hippocampal volume in males was related to testosterone level, with High Testosterone males having significantly larger hippocampi than Low Testosterone males. Similarly, there was a significant influence of plasma estradiol level on hippocampal volume and left dentate gyrus width, with High Estradiol females having larger hippocampi and dentate gyrus width than Low Estradiol females. In addition, consistent with previous findings in the laboratory rat, there were sex differences favouring males in right dentate gyrus width. These findings show that there is a complex relationship between hippocampal volume, dentate gyrus width and gonadal hormone levels in male and female meadow voles.