全文获取类型
收费全文 | 91581篇 |
免费 | 10077篇 |
国内免费 | 2170篇 |
专业分类
耳鼻咽喉 | 328篇 |
儿科学 | 1560篇 |
妇产科学 | 861篇 |
基础医学 | 6657篇 |
口腔科学 | 3050篇 |
临床医学 | 12143篇 |
内科学 | 11723篇 |
皮肤病学 | 955篇 |
神经病学 | 5203篇 |
特种医学 | 2037篇 |
外国民族医学 | 11篇 |
外科学 | 7896篇 |
综合类 | 13455篇 |
现状与发展 | 10篇 |
一般理论 | 27篇 |
预防医学 | 13157篇 |
眼科学 | 1131篇 |
药学 | 11022篇 |
523篇 | |
中国医学 | 7350篇 |
肿瘤学 | 4729篇 |
出版年
2024年 | 371篇 |
2023年 | 1860篇 |
2022年 | 3121篇 |
2021年 | 4886篇 |
2020年 | 5433篇 |
2019年 | 3877篇 |
2018年 | 3615篇 |
2017年 | 4080篇 |
2016年 | 4023篇 |
2015年 | 3651篇 |
2014年 | 6926篇 |
2013年 | 7335篇 |
2012年 | 5966篇 |
2011年 | 6272篇 |
2010年 | 4854篇 |
2009年 | 4454篇 |
2008年 | 4281篇 |
2007年 | 4204篇 |
2006年 | 3680篇 |
2005年 | 3006篇 |
2004年 | 2552篇 |
2003年 | 2336篇 |
2002年 | 1889篇 |
2001年 | 1503篇 |
2000年 | 1189篇 |
1999年 | 952篇 |
1998年 | 808篇 |
1997年 | 765篇 |
1996年 | 648篇 |
1995年 | 567篇 |
1994年 | 504篇 |
1993年 | 417篇 |
1992年 | 411篇 |
1991年 | 345篇 |
1990年 | 349篇 |
1989年 | 316篇 |
1988年 | 312篇 |
1987年 | 272篇 |
1986年 | 230篇 |
1985年 | 288篇 |
1984年 | 240篇 |
1983年 | 158篇 |
1982年 | 176篇 |
1981年 | 150篇 |
1980年 | 137篇 |
1979年 | 83篇 |
1978年 | 65篇 |
1977年 | 52篇 |
1976年 | 73篇 |
1975年 | 47篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
71.
JOHN P. BOURKE LYNNE HOWELL ALAN MURRAY WILLIAM E. HILL J. CAMPBELL COWAN KEVIN BEATT JOAN ERRINCTON STUART JAMESON RONALD G. GOLD 《Pacing and clinical electrophysiology : PACE》1989,12(8):1419-1425
A randomized prospective study was undertaken to compare the electrical performances of three permanent, endocardial, tined pacing leads with different electrode designs--sintered platinum, vitreous carbon, and porous carbon. Ninety-nine patients received one of the leads (S80 31; 423S 32; S100 36). Acute R wave amplitude and ST elevation of the native endocardial electrogram, voltage threshold, impedance, and current flow at four pulse durations (0.25-1.0 msec) were measured. Voltage thresholds were measured noninvasively at each of four pulse durations at 2 days and 1, 3, and 6 months after implantation. No significant differences were found in sensing properties, or current flow at threshold at 0.5 msec pulse duration. The 423S lead had a significantly higher impedance at threshold and both a higher impedance and lower current flow at 5 V. No significant differences in threshold voltages were found between the three leads at any pulse duration, at any of the assessed times after implantation. Six-month thresholds for the S80, 423S, and S100 leads were 1.18 +/- 0.35, 1.17 +/- 0.29, and 1.06 +/- 0.38 V respectively at 0.5 msec pulse duration. Differences between 'high performance' pacing leads need to be of a greater order of magnitude before they can be exploited to give any real clinical advantage to patients. 相似文献
72.
73.
K. W. Stephen J. I. Russell S. L. Creanor C. K. Burchell 《Community dentistry and oral epidemiology》1987,15(2):90-94
Fibre optic transillumination (FOTI) has been employed during the course of a 3-yr clinical dentifrice trial which initially involved 3003 children. At the initial examination, a subgroup of 813 13-yr-olds, and at the following annual visit, 2247 14-yr-olds, were examined using a 150 W lamp and 0.5 mm diameter probe. Routine clinical and radiographic examinations were performed separately. Compared to the clinical scores for anterior teeth, FOTI detected an additional 64% of interproximal lesions at the first visit while, for the larger number of children at the second visit, the increase in lesion detection level using FOTI was 37%. For the posterior teeth the comparable figure at the second examination was 92%. When FOTI data were compared to radiographic data for more than 52,000 posterior interproximal surfaces, FOTI could only detect 17% of radiographic Grade 2 lesions and 48% Grade 3 lesions. Thus any assumption that FOTI diagnoses may be a substitute for bitewing radiography appears premature. 相似文献
74.
Summary Bronchus stump insufficiency following lung resection, with an average incidence of 4%, is a serious complication which carries a mortality of up to 90%. Operative transthoracic approaches have been largely unsatisfactory because of the high operative risk and rapidly spreading infection. In an experimental study on 18 pigs, endoscopic occlusion of infected bronchus stump fistulae was achieved with fibrin sealant (1 ml, 500 units/ml thrombin, 3500 units/ml aprotinin) applied via a flexible bronchoscope. During autopsy, all bronchus stump fistulae were found to have healed after the second postoperative week. Transitory local abscesses of the pleura could be prevented by high-dose systemic antibiotic therapy for 5 postoperative days but not by antibiotics added to the fibrin sealant. This endoscopic method has already been performed successfully in 3 clinical cases; additional sclerotherapy with (2–3 ml Ethoxysclerol applied around the fistula orifice was carried out before fibrin sealing to stimulate fibrosis. Endoscopic controls demonstrated fistula closure by granulation tissue after 2 weeks. This procedure could become the method of choice for infected postoperative fistulae of the bronchus stump and should be attempted in any case before operative approaches are considered. 相似文献
75.
生理影像是功能性医学影像的一个重要分支,也是临床医学工程的一个极其重要的研究和应用领域。多年来,作者及其研究生与临床医务人员相结合,在电生理影像和热生理影像的信息获取和数字化处理技术方面进行了大量及深入的研究,提出了一种体内热估计(ITE)新技术。本文重点介绍热生理影像信息在妇女乳腺癌诊断中的应用。通过对约五千例妇女乳腺病筛选的结果,表明了生理影像信息处理及ITE技术在临床医学上的应用价值。 相似文献
76.
目的探讨保留齿状线加皮桥重建闭合切口治疗环状混合痔的可行性及疗效。方法治疗组选用保留齿状线加皮桥重建闭合切口32例,与对照组采用传统外剥内扎治疗34例在术后疼痛、水肿、出血、痔残留等并发症及住院时间、愈合时间等方面进行比较。结果治疗组在术后疼痛、水肿、出血、痔残留等及住院时间、愈合时间等方面均优于对照组。结论保留齿状线加皮桥重建闭合切口治疗环状混合痔安全、有效、可行。 相似文献
77.
AIMS: The efficacy of three education programmes for Type 2 diabetic patients was tested in a randomized trial. A didactic-oriented training programme (treatment A) was compared with a self-management-oriented programme delivered in group sessions (treatment B). The latter programme was compared with a more individualized approach (treatment C). METHODS: One hundred and eighty-one Type 2 diabetic patients (age 55.6 +/- 6.3 years, diabetes duration 6.6 +/- 6.2 years, HbA(1c) 7.8 +/- 1.6%, female 49.7%) took part. Efficacy was assessed 3 months (t1) after baseline (t0) and at a follow-up 15 months (t2) after baseline. RESULTS: The fall in HbA(1c) in treatment B at t1 was sustained at t2 (t0 8.1 +/- 1.8%, t1 7.3 +/- 1.7%, t2 7.4 +/- 1.9%). In treatment A, HbA(1c) was unchanged throughout (t0 7.6 +/- 1.5%, t1 7.5 +/- 1.3%, t2 7.7 +/- 1.7%; treatment A vs. treatment B; P < 0.05). With the more individualized approach of treatment C, there was a fall in HbA(1c) at t1, but this was not sustained at t2 (t0 7.8 +/- 1.6%, t1 7.1 +/- 1.3%, t2 7.6 +/- 1.6%; treatment B vs. treatment C; P = 0.73). There were also significant benefits in treatment B subjects compared with treatment A in further medical (body mass index and fasting blood glucose), psychological (control, irritability and hunger dependency of eating behaviour, and trait anxiety) and behavioural (exercise) variables. There were no significant benefits of the more individualized treatment C compared with group treatment B. No significant differences were found regarding triglyceride levels, high-density lipoprotein, diabetes-related knowledge, negative well-being, urine or blood glucose levels or foot care. CONCLUSION: Self-management training had a significantly higher medium-term efficacy than didactic diabetes education. The group sessions were more effective than a more individualized approach. 相似文献
78.
79.
80.
Hirotsugu Yamada MD PhD Zoran B. Popovic MD PhD David O. Martin MD MPH Kenneth C. Civello MD MPH Don W. Wallick PhD 《Heart rhythm》2006,3(6):722-727
BACKGROUND: Coupled pacing (CP), which consists of delivering a premature electrical stimulation to the heart after the effective refractory period of ventricular activation, is a novel method for controlling ventricular rate during atrial fibrillation (AF). It also has been established that CP improves pump function by enhancing external cardiac work and myocardial efficiency. OBJECTIVE: The purpose of the present study was to determine if two time delays for CP (short and long) would result in similar improvements in ventricular function. METHODS: In a canine model, we applied CP at two time delays (CP-S and CP-L) during two stages: sinus rhythm (SR) and acute AF. The cardiac responses to CP during SR served as the nontachycardic and nondepressed control. During both rhythms, we shortened the coupling interval until we obtained maximal contractility, designated CP-S. Next, we increased the delay until we started to see a measurable secondary contraction (left ventricular pressure development of approximately 20 mmHg). These longer delays were designated CP-L. RESULTS: Our results showed that the ventricular rate of intrinsic activation (VRIA) remained decreased despite prolongation of the time delay of CP during both AF and SR. Also, both delays of CP increased left ventricular systolic pressure (LVSP) and dLVP/dt, which are indices of myocardial contractility. In contrast, CP increased external cardiac work only during AF. Prolonging this time delay did not markedly decrease the improvement in external cardiac work. Myocardial O(2) consumption (MVO(2)) did not significantly change as the result of CP during either SR or AF. Finally, myocardial efficiency improved during AF as the result of CP at both time delays. CONCLUSIONS: In conclusion, shorter time delays for CP increased contractile strength during both SR and AF. However, extending the time delay of CP had minimal effects on diminishing the improved ventricular pump function and energetics that resulted from CP during AF. Thus, the maximal enhancement of myocardial contractility via CP-S was not needed to maintain the improved ventricular function during acute AF when CP is applied. 相似文献