全文获取类型
收费全文 | 68969篇 |
免费 | 2597篇 |
国内免费 | 599篇 |
专业分类
耳鼻咽喉 | 402篇 |
儿科学 | 786篇 |
妇产科学 | 659篇 |
基础医学 | 7734篇 |
口腔科学 | 3524篇 |
临床医学 | 5260篇 |
内科学 | 12974篇 |
皮肤病学 | 1386篇 |
神经病学 | 5171篇 |
特种医学 | 1697篇 |
外国民族医学 | 6篇 |
外科学 | 12959篇 |
综合类 | 3889篇 |
现状与发展 | 1篇 |
一般理论 | 5篇 |
预防医学 | 5111篇 |
眼科学 | 1202篇 |
药学 | 4093篇 |
20篇 | |
中国医学 | 2653篇 |
肿瘤学 | 2633篇 |
出版年
2023年 | 607篇 |
2022年 | 1076篇 |
2021年 | 2134篇 |
2020年 | 1354篇 |
2019年 | 5165篇 |
2018年 | 5418篇 |
2017年 | 3487篇 |
2016年 | 1119篇 |
2015年 | 1100篇 |
2014年 | 1950篇 |
2013年 | 1980篇 |
2012年 | 1534篇 |
2011年 | 1785篇 |
2010年 | 1539篇 |
2009年 | 1229篇 |
2008年 | 1236篇 |
2007年 | 1205篇 |
2006年 | 1099篇 |
2005年 | 924篇 |
2004年 | 773篇 |
2003年 | 782篇 |
2002年 | 576篇 |
2001年 | 608篇 |
2000年 | 488篇 |
1999年 | 472篇 |
1998年 | 291篇 |
1997年 | 273篇 |
1996年 | 261篇 |
1995年 | 246篇 |
1994年 | 199篇 |
1993年 | 174篇 |
1992年 | 155篇 |
1991年 | 146篇 |
1990年 | 101篇 |
1989年 | 105篇 |
1988年 | 99篇 |
1987年 | 103篇 |
1985年 | 2831篇 |
1984年 | 3389篇 |
1983年 | 2865篇 |
1982年 | 3336篇 |
1981年 | 3024篇 |
1980年 | 2515篇 |
1979年 | 2500篇 |
1978年 | 2063篇 |
1977年 | 1530篇 |
1976年 | 1991篇 |
1975年 | 1513篇 |
1974年 | 1323篇 |
1973年 | 1271篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
61.
Takashi Toyonaga Eisei Nishino Toshio Dozaiku Chie Ueda Tomoomi Hirooka 《Digestive endoscopy》2007,19(Z1):S14-S18
The gastric vasculature responsible for intraoperative bleeding in endosocpic submucosal dissection (ESD) is the ramified vascular network occupying the middle of the submucosal layer and large vessels penetrating the muscle layer. Appropriate management for these vessels must be addressed. The trimming of the ramified vascular network can be safely performed with coagulation mode following shallow mucosal cutting. A large penetrating vessel usually requires precoagulation prior to dissection. These procedures are effectively performed with the water jet short needle knife (Flush knife). 相似文献
62.
The effectiveness of interdisciplinary treatments for chronic pain is well established. In general, these treatments decrease psychosocial distress and increase physical abilities. Further, return to work rates following interdisciplinary treatment tend to be quite high. Previous studies have highlighted a number of factors that individually influence return to work rates; however, there is a need for more comprehensive and unified models that allow an evaluation of the inter-relations among these factors. The present investigation examined how demographic and treatment outcome variables interacted to influence post-treatment return to work rates in a sample of individuals with chronic pain following interdisciplinary treatment. Results indicated that patient age, lifting ability, pain duration, depression level, and reported disability were individually related to return to work; however, when these variables were evaluated relative to one another, level of depression and patient age had the best ability to predict post-treatment work status. These results add to the literature by specifically highlighting post-treatment factors that best discriminate patients who had returned to work from those that had not. Furthermore, they provide evidence that general emotional distress is perhaps the most important predictor of work status following treatment. 相似文献
63.
支气管扩张症辨证模式初探 总被引:4,自引:0,他引:4
目的:探讨支气管扩张症的中医辨证分型规律及证候特点.方法:通过对563例支气管扩张症的临床流行病学调查,采集以症状、体征、舌、脉及相关理化检测为变量的基本信息,以频数分析、聚类分析、方差分析等方法,提炼支气管扩张症的证候分布规律及证候特点.结果:临床上支气管扩张症多见4种证候类型,分别为痰热壅肺证(45.65%)、肝火犯肺证(24.51%)、肺脾气虚证(22.38%)、气阴两虚证(7.46%).结论:较大样本的临床流行病学调查为研究支气管扩张症辨证分型规律提供了科学依据,并可以通过主症判别分析法建立证候识别模式,为临床实践提供依据. 相似文献
64.
L. Kalinauskiene D. Cekuoliene M. H. Van IJzendoorn † M. J. Bakermans-Kranenburg † F. Juffer† I. Kusakovskaja 《Child: care, health and development》2009,35(5):613-623
Objective This randomized control trial examined the effects of a short-term, interaction-focused and attachment-based video-feedback intervention (VIPP: video-feedback intervention to promote positive parenting).
Design VIPP effect on mothers' sensitive responsiveness and infant–mother attachment security was evaluated in a sample ( n = 54) of low sensitive, non-clinical, middle class Lithuanian mothers.
Methods Maternal sensitivity was assessed in a free play session with the Ainsworth's sensitivity scale, and attachment security was observed using the Attachment Q sort for home observations.
Results We found that the intervention mothers indeed significantly improved their sensitive responsiveness through participation in our VIPP. The effect size was large according to Cohen's criteria, d = 0.78. VIPP enhanced maternal sensitive responsiveness even when maternal age, educational level, depression, daily hassles, efficacy, infant gender, and infant negative and positive affect were controlled for. However, attachment security in the VIPP infants was not enhanced after the intervention, compared with the control infants, and the infants did not seem to be differentially susceptible to the increase in maternal sensitivity dependent on their temperamental reactivity.
Conclusion We suggest that a relatively brief and low-cost programme can provide effective support for mothers who lack sensitivity in the interactions with their infants. 相似文献
Design VIPP effect on mothers' sensitive responsiveness and infant–mother attachment security was evaluated in a sample ( n = 54) of low sensitive, non-clinical, middle class Lithuanian mothers.
Methods Maternal sensitivity was assessed in a free play session with the Ainsworth's sensitivity scale, and attachment security was observed using the Attachment Q sort for home observations.
Results We found that the intervention mothers indeed significantly improved their sensitive responsiveness through participation in our VIPP. The effect size was large according to Cohen's criteria, d = 0.78. VIPP enhanced maternal sensitive responsiveness even when maternal age, educational level, depression, daily hassles, efficacy, infant gender, and infant negative and positive affect were controlled for. However, attachment security in the VIPP infants was not enhanced after the intervention, compared with the control infants, and the infants did not seem to be differentially susceptible to the increase in maternal sensitivity dependent on their temperamental reactivity.
Conclusion We suggest that a relatively brief and low-cost programme can provide effective support for mothers who lack sensitivity in the interactions with their infants. 相似文献
65.
枕骨大孔区腹侧脑膜瘤的显微手术技术探讨 总被引:1,自引:0,他引:1
目的探讨远外侧入路在治疗枕骨大孔区腹侧脑膜瘤中的应用。方法对14例脑膜瘤患者采用远外侧入路显微手术治疗,其中枕髁后入路8例,经部分枕髁入路3例,经C1、2关节面侧方联合部分枕髁入路2例,经完整枕髁入路1例。结果肿瘤全切11例,次全切除3例;1例行枕颈融合,无手术死亡病例。所有患者术后均未出现寰枕关节不稳定的症状,手术并发症主要是后组颅神经损伤、椎动脉损伤、脑脊液漏以及脑干缺血。结论远外侧入路是手术治疗下斜坡区和上段颈髓腹侧、腹外侧病变的理想入路,可以理想显露肿瘤及其基底部并减少术中出血,但手术操作比较复杂且具有一定的风险。 相似文献
66.
作者采用特异性胃动素(MTL)抗体,通过放射免疫法,对8例16~40周龄的人胎儿胃液、胆汁及胃粘膜、胆囊组织MTL含量进行探测。结果显示:MTL含量胃液为46.00±12.87pmol/L,胆汁为29.89±15.45Pmol/L;胃粘膜为1.34±0.45pmol/g,胆囊为0.87±0.32pmol/g.胃液、胃粘膜MTL含量分别高于胆汁及胆囊MTL水平(P<0.05)。相关分析显示:胃液与胃粘膜MTL含量,胆汁与胆囊MTL含量均呈显著正相关(N=8,r=0.8933,P<0.01;N=8,r=0.9016,P<0.01)。胃粘膜MTL含量与胎龄增长也呈显著正相关(N=8,r=0.7321,P<0.05)。 相似文献
67.
Isao Kurosaki Kazuhiro Tsukada Hidenori Ueki Akira Ohya Katsuyoshi Hatakeyama 《Journal of Hepato-Biliary-Pancreatic Surgery》1997,4(1):131-134
We report a case of advanced gallbladder cancer in a 37-year-old man who presented in June 1993 with malignant obstructive jaundice. After percutaneous transhepatic biliary drainage and several diagnostic imaging examinations, the patient underwent laparotomy under a diagnosis of extremely advanced gallbladder cancer involving the confluence of the hepatic ducts. The tumor, however, was judged to be unresectable because of its massive spread into the liver along Glisson's sheath, and because of histologically proven peritoneal dissemination. After exploratory laparotomy, one course of anticancer chemotherapy (cisplatin, 100 mg/body IV, on day 1, and 5-fluorouracil, 1000 mg/body, on days 1–5, by continuous infusion) was administered and the completely obstructed hepatic duct was dramatically re-canalized. Four courses of chemotherapy were administered over a 16-month period until jaundice recurred. For these 16 months, the patient's quality of life was well maintained without biliary drainage. He died of increased peritoneal dissemination approximately 2 years after the first course of anticancer chemotherapy. 相似文献
68.
This paper discusses the use of the Milgram obedience experiments and the Tuskegee syphilis study in the bioethical literature. The two studies are presented and a variety of uses of them identified and discussed. It is argued that the use of these studies as paradigms of problematic research relies on a reduction of their complexity. What is discussed is thus often constructions of these studies that are closer to hypothetical examples than to the real studies. 相似文献
69.
我院自1969年7月至1990年7月,收治各种类型的胆道系统疾病共2018例,施行胆囊切除和胆总管切开取石以及其他各种胆道手术等共1821例,其中发现胆囊息肉样病变23例,术后经病理检查证实,其发病率占1.14%.23例胆囊息肉样病变同时并发急性胆囊炎、慢性胆囊炎、胆囊炎合并结石、胆囊出血、胆囊息肉癌变等并发症.本文着重讨论了并发症的原因,诊断方法以及如何治疗等问题.作者认为该病在胆道系统疾病中占有重要的地位,也是胆道系统中一种特殊的疾病. 相似文献
70.
临床医师处方抗菌药物前需思考的几个问题 总被引:20,自引:0,他引:20
2001年和2003年卫生部全国医院感染监测网调查结果均显示,医院横断面抗菌药物的平均使用率在54%以上,联合用药较为普遍.国内监测结果也表明细菌耐药性日益严重.针对上述问题,提出临床医师在面对病人开处方抗菌药物之前,须思考的问题:是否有使用抗菌药物的适用症?是否了解选用的抗菌药物,选用何种药物?是否有联合使用抗菌药物的指征?采用何种给药途径、给药剂量、给药时间?是否属于特殊宿主或针对特殊病原体的感染使用抗菌药物?密切观察抗菌药物治疗是否有效?针对局部感染是否需要穿刺或外科手术引流病灶?是否已出现抗菌药物的不良反应?是否存在药物相互作用?是否存在不合理使用抗菌药物情况?并且针对每个问题提出了建议. 相似文献