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71.
In a retrospective study using univariate analysis, we identified tumor type (nonendometrioid vs endometrioid), depth of myoinvasion (MI), mode of MI (infiltrative vs cohesive), and direct anatomic invasion of the cervical wall from the isthmus as significant positive risk factors for intramyometrial lymphvascular space involvement (LVSI). On multivariate analysis, tumor grade, depth of MI, and mode of MI retained their significance. We created a grid for the relative risks of LVSI with respect to these variables individually or in combination. We suggest that our indirect estimate of the risk of LVSI can help in assessing prognosis and determining the need for adjuvant therapy whenever LVSI is important in clinical decision making, but its pathologic diagnosis is uncertain. 相似文献
72.
《中华骨科杂志》2002-2004年引文分析 总被引:2,自引:0,他引:2
目的研究《中华骨科杂志》文献引用规律及我国骨科学研究领域科研人员的文献利用与需求特征。方法利用引文计量分析法,统计《中华骨科杂志》2002-2004年间刊载的614篇论文所引用的参考文献。结果614篇论文中,有引文的论文共565篇,引文率为92.02%,篇均引文11.66条;引文中期刊6672条(93.22%),图书451条(6.30%);普赖斯指数45.44%,期刊自引361条,自引率5.04%。被引用频次居前20位的中、外文期刊的引文量占总引用期刊引文量的53.30%。结论《中华骨科杂志》涉猎文献范围广,引文类型以期刊为主,语种以英文文献为主,引文的外文语种结构较为单一,研究引用文献比较滞后,文献半衰期较长,专业人员利用近5年内新文献的能力有待于进一步提高。 相似文献
73.
灰关联分析应用于因素分析时关联度指标的改进 总被引:8,自引:1,他引:7
本文指出在应用灰关联分析进行因素分析时传统的关联度计算方法的不足,并提出采用新的关联度指标来表示因素之间的关联关系,同时给出了实例介绍计算方法。 相似文献
74.
Health-related quality of life assessed before and during chemotherapy predicts for survival in multiple myeloma 总被引:5,自引:0,他引:5
Measurement of health-related quality of life was integrated into a randomized trial (NMSG 4/90) comparing melphalan/prednisone to melphalan/prednisone + interferon α-2b in newly diagnosed multiple myeloma. One of the aims of the study was to assess the prognostic significance of quality-of-life scores, using the EORTC QLQ-C30 questionnaire. Univariate analysis showed a highly significant association with survival from the start of therapy for physical functioning as well as role and cognitive functioning, global quality of life, fatigue and pain. In multivariate analysis, physical functioning and W.H.O. performance status were independent prognostic factors ( P values=0.001 for both) when analysed in a Cox regression model with the somatic variables β-2 microglobulin, skeletal disease and age. The best prediction for survival from the start of therapy was obtained by combining the β-2 microglobulin and physical functioning scores in a variable consisting of three risk factor levels with an estimated median survival of 17, 29 and 49 months, respectively. At a 12 months landmark analysis, the relative risk for patients with physical functioning score 0–20 v 80–100 was 5.63 (99% CI 2.76–11.49), whereas the relative risk for patients without an objective response to chemotherapy compared to those with at least a minor response was 2.32 (99% CI 1.44–3.74). Quality-of-life assessment may be an independent and valuable addition to the known prognostic factors in multiple myeloma. 相似文献
75.
H. D. Tagare K. W. Elder D. M. Stoner R. M. Patterson C. L. Nicodemus S. F. Viegas Dr. G. R. Hillman 《Annals of biomedical engineering》1993,21(6):715-726
The carpal regions of ten cadaver extremities were imaged by CT. The images were combined into a 3-dimensional model of the
carpus using a technique based on a dynamic programming algorithm to find an optimal estimate of the location of the bone
boundaries in the CT images. The resulting set of surface points on each bone was used to compute volumes and principal and
antipodal axes for the bones. A spatial coordinate system was established based on the positions of the centroids of three
bones in the distal carpal row. The angular orientations of all carpal bones were determined with respect to this system.
The principal axes for the same bone among ten wrist specimens proved to be more widely dispersed than the antipodal axes
for the same bones. The antipodal axes also correspond more closely to an intuitive notion of the “longest axis” of the bones.
We conclude that the antipodal axis is a more reliable and useful measure of bone orientation than the principal axis. 相似文献
76.
Carlo Bertucci Enrico Domenici Piero Salvadori 《Journal of pharmaceutical and biomedical analysis》1990,8(8-12):843-846
The application of a circular dichroism (c.d.) detection system in HPLC using a chiral stationary phase is presented. The simultaneous measurement of the absorbance and c.d. signal allows the evaluation of the anisotropy factor (g = Δ/) and thus the determination of the enantiomeric excess (e.e.) of the eluates. When this detection system is used in preparative chiral chromatography the collection of the enantiomeric fractions can be readily optimized. 相似文献
77.
Jen auo Hirschberg 《Early child development and care》1990,65(1):57-69
During a period of twenty years [1969-1988] the author has observed 614 cases of congenital malformations and noninflammatory diseases of the larynx in infants and young children, Budapest. He summarizes the most characteristic symptoms of laryngeal pathology in infants, and discusses the diagnostic possibilities. Among the latter, spectrographic analyses complemented by auditory evaluation of pathological cry and different breathing noises play an important role. Based on his investigation author differentiates 20 kinds of pathological crying sounds and 4 basic forms of stridor. He describes the acoustic attributes of different pathological sound phenomena and summarizes characteristic voice changes. 相似文献
78.
放射性肝纤维化过程的定量研究 总被引:6,自引:0,他引:6
经^60Coγ线照射大鼠肝区,通过光镜、电镜和图像分析仪、宣研究了照后1年肝脏的病理改变。结果表明,30Gy组在照射后1年内逐渐发生了放射性肝纤维化病变。在肝纤维化发生过程中,肝细胞内糖原颗凿含量进行性减少,间质中胶原纤维含量进行性增加,网状纤维于照射1-3个月呈进行性增加。 相似文献
79.
J. Rutenfranz W. Ottmann B. Neidhart W. Brockmann 《International archives of occupational and environmental health》1988,61(1-2):89-93
Summary A typical shiftwork experiment was chosen to prove the validity of an automated procedure for the analysis of free noradrenaline and adrenaline in urine. The method consists of a column switching technique with an adsorption/elution clean-up and a reversed phase high performance liquid chromatography followed by chemical reaction detection based on the trihydroxyindole method. The analysis of variance was performed using a second data set obtained by a semi-automated procedure for which the accuracy had already been confirmed. The analysis of covariance showed that for field studies, as well as for laboratory experiments in which the variances contributed by the experiments themselves are greater than 10% rel., the data sets of the two methods provide the same information.Dedicated to Prof. H. Hartkamp, University of Wuppertal, on the occasion of his 60th birthday 相似文献
80.
笔者对13例良性小脑出血的患者,从起病、临床表现进行了具体分析.总结出中老年良性小脑出血的6个特点,供临床工作者参考. 相似文献