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排序方式: 共有8361条查询结果,搜索用时 0 毫秒
31.
Ruan Zhongbao Geng Qian Ma Genshan Chen Xiangjian Zhang Jinan Cao Kejiang Ma Wenzhu 《南京医科大学学报(英文版)》2000,14(2):64-68
[1]Richardson CP, Mckenna RM, Bristow CM, et al.Report of the 1995 Word Health Organization/International Society and Federation of Cardiology Task Force on the definition and classification of cardiomyopathies. Circulation, 1996,93: 841
[2]Barr CS, Naas A, Freeman M, et al. QT dispersion and sudden unexpected death in chronic heart failure. Lancet, 1994,343:327
[3]Martin AB, Garson A, Perry JC, et al. Prolonged QT interval in hypertropic and dilated cardiomyopathy in children. Am Heart J, 1994,127(1):64
[4]Pye M, Quinn AC, Cobble SM. QT dispersion: a non-invasive marker of susceptibility to arrhythmia in patients with sustained ventricular arrhythmias?Br Heart J, 1994,71(5):51
[5]Berger RD, Kasper EK, Baughman KL, et al. Beat to beat QT interval variability: novel evidence for repolarization lability in ischemic and non ischemic dilated cardiomyopathy. Circulation, 1997, 96 (5):1557
[6]Wolfram G, Ulrike S, Volker M, et al. QT dispersion and arrhythmic events in idiopathic dilated cardiomyopathy. Am J Cardiol, 1997,78: 458
[7]Fei L, Goldman JH, Prasal K, et al. QT dispersion and RR variations on 12-lead ECGs in patients with congestive heart failure secondary to idiopathic dilated cardiomyopathy. Eur Heart J, 1996,17: 258
[8]Pan YZ, Guo NS, Xing ZF, et al. The relation between QT dispersion and ventricular arrhythmia of dilated cardiomyopathy. Chin J Inter Medi, 1996,35(11):73
[9]Galinier M, Vialette JC, Fourcade J, et al. QT interval dispersion as a predictor of arrhythmic events in congestive heart failure. Importance of aetiology. Eur Heart J, 1998,19(7) :1054 相似文献
32.
正常及突变MyBPC与肌凝蛋白结合功能的对比研究 总被引:2,自引:1,他引:1
目的 比较正常及突变 My BPC与肌凝蛋白的结合功能 .方法 重叠 PCR法制备正常及突变 My BPC的表达载体 ,大肠杆菌 BL- 2 1中表达并提纯蛋白 . 10 0 μL 含 2 .2 μmol· L- 1肌凝蛋白溶液中 ,分别加入不同浓度 My BPC蛋白 ,经离心、 SDS- PAGE,密度法测定两者的结合率 .结果 3774D1 8,32 2 3S1 4 0 结合率分别为 (6 8.2 0± 1.72 ) % ,(2 4.41±2 .10 ) % ,较正常 My BPC (82 .70± 2 .44 ) %显著降低 (n=5 ,P<0 .0 1) .结论 为家族性肥厚型心肌病突变基因的“肽类毒剂”致病学说提供了依据 相似文献
33.
Dramatic improvement of severe dilated cardiomyopathy in an acromegalic patient after treatment with octreotide and trans-sphenoidal surgery 总被引:1,自引:0,他引:1
LEGRAND V.; BECKER A.; PHAM V. T.; DEMOUUN J.C.; STEVENAERT A. 《European heart journal》1994,15(9):1286-1289
Severe congestive heart failure developed in an acromegalicpatient, and was successfully treated with octreotide followedby trans-sphenoidal surgery. Clinical, hormonal echocardiographicand haemodynamic findings as well as histological heart examinationbefore and after treatment revealed tliat over-production ofgrowth hormone may induce the myocardial cell degeneration responsiblefor mechanical heart dysfunction. In addition, this unique exampledemonstrates the reversibility of myocardial damage followingoctreotide and trans-sphenoidal surgery, leading to significantimprovement in cardiac function with minimal diastolic dysfunctionand moderate interstitial fibrosis. 相似文献
34.
目的:用VDD心脏起搏治疗1 例肥厚性梗阻型心肌病(HOCM),并观察其临床及血流动力学效果。 方法:常规方法植入VDD型心脏起搏系统,设置房室起搏间期120 m s,心房感知0.15 m V,起搏前后进行左室流出道压力阶差等血液动力学对比观察。 结果:术后房室同步起搏率为100% ,左室流出道压力阶差从6.8 kPa(51.4m m Hg)降至2.813 kPa(21.1 m m Hg),二尖瓣前移现象消失,临床症状明显改善,随访期间未再出现晕厥。 结论:VDD起搏植入简便、房室同步功能稳定,对HOCM 患者不失为一种新的有效的治疗方法。 相似文献
35.
为评价超声心动图对扩张性心肌病(DCM)患者左室舒张功能的诊断价值。方法:用超声心动图 和放射性核素显像(RNV)对20例DCM患者和20例同龄正常人的左室舒张功能进行对照分析。结果:DCM组左室 舒张功能RNV指标峰充盈率(PFR)明显降低,同对照组比较差异有显著性(P<0.05);超声指标二尖瓣血流频谱早 期充盈峰速度(νE)、晚期充盈峰速度(νA)、νA/νE等参数同对照组比较无明显差异(P>0.05),表现为“正常”。结 论:超声心动图舒张功能指标νE、νA、νA/νE不能真实反映DCM患者的左室舒张功能。 相似文献
36.
The case of a 17-year-old male patient with severe end-stage dilated cardiomyopathy and a large thrombus formation within the cavum of the left ventricle is reported. After an acute thrombectomia combined with a partial left ventriculectomy (Batista procedure), the patient was successfully treated with an appropriate left ventricular assist device (LVAD) system using a centrifugal nonocclusive pump (Biomedicus, Medtronic, Anaheim, CA, U.S.A.). Mechanical support was removed on Day 9, and the patient was discharged from the hospital on Day 19. The effectiveness of emergency mechanical support in patients with very unfavorable prognoses is discussed. 相似文献
37.
Toshiro Kita Kentaro Kasai Noriyuki Tanaka Toru Nagano 《International journal of legal medicine》1996,109(1):37-41
The purpose of the study was to show whether it was possible to produce alcoholic cardiomyopathy by short-term alcohol ingestion combined with an infinitesimally low endotoxin injection. Wistar rats were fed an alcoholic liquid diet according to the formula of Lieber and Decarli, and challenged with an injection ofE. coli lipopolysaccharide (LPS) endotoxin (1.0 g/g body weight per day for ten weeks). After ten weeks alcohol diet combined with LPS challenge, light microscopical examination showed changes commonly seen in alcoholic cardiomyopathy such as hypertrophy, oedema and disarray of myofibers. By electron microscopy, degeneration of mitochondria and degeneration of myocardial fibers were observed, the latter showing disturbance of the myofibrilla arrangement and interstitial fibrosis. Rats on an alcoholic liquid diet and rats challenged with a single identical doses of LPS did not show characteristic histological findings of alcoholic cardiomyopathy. These results suggest that short-term alcohol ingestion combined with an infinitesimally low endotoxin injection experimentally produces alcoholic cardiomyopathy, and may support the idea that endotoxin plays an important role in the aetiology of alcoholic cardiomyopathy. 相似文献
38.
TENDERA M.; SCHNEEWEISS A.; BARTOSZEWSKI A.; POLONSKI L.; WODNIECKI J.; SALAMON A. 《European heart journal》1993,14(3):410-415
We studied the correlation between changes in left ventricularfilling dynamics induced by acute intravenous administrationof verapamil and the changes in exercise tolerance induced byoral administration of the agent in 30 patients with hypertrophiccardiomyopathy. Diastolic cardiac function was measured by meansof a nuclear stethoscope before and 10 min after intravenousadministration of verapamil, 0.15mg. kg1 over 2 min.Treadmill exercise tests using a modified Bruce protocol wereperformed before the initiation of oral verapamil treatmentand after 4 weeks of oral therapy at a dose of 320360mg. day1 (mean±SD 332±17mg. day1). Peak filling rate (PFR) increased in 21 patients, 18 of whom(86%) also had an increase in exercise duration. PFR showedno increase in nine patients, eight of whom (89%) had no changein exercise duration (sensitivity 95%, specificity 73%, predictivevalue of the positive result 86%, predictive value of the negativeresult 89%). Acute changes in time from the beginning of rapidfilling to PFR (t-PFR) and in left ventricular end-diastolicvolume (EDV) were less useful in predicting improvement in exercisetolerance. In 19 patients the changes in PFR and EDV parallelled.Twelve of the 13 patients (92%) will an increase in both parametersalso had an increase in exercise duration, whereas all six inwhom these parameters were reduced showed no increase in exerciseduration (sensitivity 100%, specificity 86%, predictive valueof positive results 92%, and predictive value of negative results100%). In conclusion, the response of PFR, and even more so the combinedresponse of PFR and EDV to intravenous verapamil, accuratelyidentify patients with hypertrophic cardiomyopathy who are likelyto show improvement in exercise tolerance after oral verapamiltherapy. 相似文献
39.
The relationship of myocarditis to dilated cardiomyopathy 总被引:2,自引:0,他引:2
MACARTHUR C. G. C.; TARIN D.; GOODWIN J. F.; HALLIDIE-SMTTH K. A. 《European heart journal》1984,5(12):1023-1035
Three patients with congestive cardiomyopathy are reported inwhom high neutralizing antibody titres to Coxsackie B viruseswere detected. At post-mortem examination, all three had histologicallydemonstrable chronic inflammation of the myocardium. The heartsof ten patients dying in cardiac failure due to other causesshowed no comparable inflammatory infiltration. This providesfurther evidence that Coxsackie B viral myocarditis is involvedin the pathogenesis of some cases of dilated cardiomyopathy. One patient also had pulmonary veno-occlusive disease. Thishas been reported in association with myocarditis once previouslyin an infant. A viral aetiology has been postulated. It seemslikely in this patient to have also been due to a CoxsackieB virus. 相似文献
40.
Zielinsky P 《Echocardiography (Mount Kisco, N.Y.)》1991,8(6):661-668
The increased incidence of hypertrophic cardiomyopathy in children of diabetic mothers has already been demonstrated, but its prenatal diagnosis has not yet been extensively studied. The purpose of this prospective study was to evaluate the frequency, severity, and echocardiographic features of fetal hypertrophic cardiomyopathy in a population with several indications for prenatal echocardiography. From March 1987 to April 1991, 283 fetuses were submitted to comprehensive prenatal echocardiography, including M-mode measurements, cross-sectional imaging, Doppler studies, and color flow mapping. One hundred seventy-six were pregnancies complicated by previous or gestational diabetes. The diagnosis of disproportionate septal hypertrophy was made in 39 fetuses (mean septal thickness 7.12 +/- 1.6 mm), at a mean gestational age of 32 weeks. Diabetes mellitus was present in 36 of these pregnancies (92.3%). In four cases, nonimmune hydrops was detected. A systolic anterior motion of the mitral valve was present in three fetuses, but only one showed a gradient across the left ventricular outflow tract. Postnatal echocardiographic examination in 27 babies did not show false positivity. In ten cases, spontaneous regression of the septal hypertrophy was shown. There were three neonatal deaths, unrelated to the myocardial disease. We concluded that transient hypertrophic cardiomyopathy is a frequent entity, especially when associated with diabetes during gestation, being a potential cause for nonimmune hydrops. Fetal echocardiography is the method of choice for its prenatal diagnosis and should always be indicated in diabetic mothers. 相似文献