A rare cause of vaginal bleeding in a 7-month-old female infant

Ovarian sex cord stromal tumor (OSCST), sclerosing type, is an extremely rare ovarian tumor. Sex hormone production by OSCST can result in isosexual or heterosexual precocious puberty in younger patients. We present a case of a 7-month-old female infant found to have a sclerosing-type OSCST that presented with vaginal bleeding and very prominent vellus hair at the mons pubis. This represents the youngest patient reported in the literature with this subset of OSCST.     

雌激素孕激素及妈富隆三种方法治疗青春期功血180例临床分析

目的:观察三种不同方法治疗青春期功血的临床疗效.方法:随机将诊断青春期功血的180例患者分为雌激素组、孕激素组和妈富隆组.结果:妈富隆组的完全止血时间较雌激素、孕激素组明显缩短(P＜0.05),不良反应明显减少(P＜0.05).结论:妈富隆用于治疗青春期功血治疗效果肯定,不良反应少,患者依从性好,值得临床推广.     

The Perioperative von Willebrand Factor Activity and Factor VIII Levels Among Alcohol Use Disorder Patients Undergoing Total Knee or Hip Replacement

Alcohol use disorder patients have a five-fold higher risk of postoperative bleeding complications. We measured the perioperative von Willebrand factor and factor VIII levels in consecutive patients with alcohol use disorder. In one university hospital, 105 patients scheduled for arthroplasty were screened, and 25 fulfilled inclusion criteria. Postoperatively, we found significantly decreased von Willebrand factor ristocetin cofactor values over time among alcohol use disorder patients and significantly different time courses of factor VIII levels between patients with and without a diagnosed alcohol use disorder. Blood loss was significantly increased among alcohol use disorder patients on their first postoperative day.     

Vapreotide: a somatostatin analog for the treatment of acute variceal bleeding

Background: Portal hypertension is a clinically important consequence of cirrhosis that can lead to morbidities such as variceal bleeding, hepatic encephalopathy and ascites. All of these outcomes carry high mortality rates. There have been several drugs created to assist with endoscopic therapy for the treatment of acute variceal bleeding. Recently, vapreotide has been studied in patients to evaluate its efficacy as treatment for acute variceal hemorrhage. Although no comparisons have been made between vapreotide and other somatostatin analogues, this drug has been shown to have efficacy in the control of acute variceal bleeding as well as reducing the risk of recurrent bleeding and death, especially when started prior to endoscopy. Objective: This paper reviews the literature regarding the basic science and clinical efficacy of vapreotide in acute variceal bleeding. Methods: We used a PubMed/Medline search in order to review the literature regarding the drug, vapreotide. Results/conclusions: Vapreotide appears to have benefit in the control of acute variceal bleeding. It is easy to administer and has few side effects, which are minor. These findings endorse the need for future trials to evaluate vapreotide and its use in acute variceal hemorrhage, a morbidity among patients with cirrhosis.     

Disorders of the Immune System

It is over 400 million years since “the first faint trace” of immunologic competence appeared in primitive vertebrates. By following the course of subsequent evolution, Dr. Good demonstrates relationships which are at once academically challenging and clinically promising. The promise—clearer understanding of immunologic deficiency states, including many cancers.     

等离子前列腺电切术后出血的相关原因及应对措施分析

目的对等离子前列腺电切术后出血的相关原因进行探讨,并总结出相应的措施,以减少此类并发症的发生。方法选取我院自2007年3月至2011年4月期间行等离子前列腺电切术的患者80例,对以上患者进行回顾性分析,以上患者采用等离子前列腺电切术的方法进行手术,对患者术后进行观察与分析,找出引起出血的相关因素,然后指导患者预防。结果出现并发症的患者有12例,有早期出血的患者2例,占16.7%,近期出血的患者7例,占58.3%,远期出血的患者3例,占25.0%。结论等离子前列腺电切术是治疗前列腺增生的有效方法,术前详细了解患者病史,术中严格按照规程操作,术后有效处理及预防措施是减少术后出血发生的关键。     

人子宫内膜内皮素与使用皮下埋植剂避孕后子宫异常出血的相关研究

目的:了解月经周期人子宫内膜内皮素(ET)含量,探讨使用长效避孕皮下埋植剂(皮埋剂)后ET的变化。方法:采用前瞻性对比研究方法,应用放免技术对27例正常健康育龄妇女的子宫内膜标本及使用皮埋剂后内膜标本进行检测。结果:增殖期和分泌期内膜ET分别为2.76±1.25和3.90±1.30 pg/mg,两组有显著性差异(P<0.05)。14例自身对照组内膜ET分别为3.38±1.17和10.86+3.93 pg/mg,两组有极显著统计学意义(P<0.001)。在使用皮埋剂不同时间,对内膜ET进行分析。使用皮埋剂1年以内组,ET均值为10.86±3.93 pg/mg,明显高于1年以上组。结论:子宫内膜ET含量呈现周期性变化,使用皮埋剂后,内膜ET水平明显高于皮埋前,且ET随皮埋时间延长有下降趋势。内膜ET增高,可能与使用皮埋剂后子宫异常出血有关。     

护理干预对消化道出血患者出院后康复的影响分析

目的探讨护理干预对消化道出血患者出院后康复的影响。方法消化道出血患者80例随机平分为两组,护理组与对照组各40例,两组都进行常规药物治疗与一般护理措施,护理组在此基础上则实行整体化的护理干预措施。结果经过护理干预后,护理组的总有效率为95.0%,对照组的总有效率为75.0%,护理组的总有效率明显好于对照组(P<0.05),差异有显著性意义。护理组的满意率为100%,对照组为75.0%,护理组的满意率明显高于对照组(P<0.05)。结论护理干预应用于消化道出血患者出院后康复能提高康复效果与患者的满意度,值得推广应用。     

关于上消化道出血的临床分析及护理总结

目的探讨上消化道出血患者的临床症状及临床护理措施。方法回顾性分析博罗县人民医院收治的81例上消化道出血的患者资料,并进行整理分析。分析患者的临床表现,并对博罗县人民医院护士采取的护理措施进行总结。结果上消化道出血的患者,主要表现为呕血和柏油样便。对此类患者,需密切观察患者的生命体征、意识变化,记录患者呕血和便血的量和性质,观察患者出血控制情况,为患者输血,遵医嘱使用止血药物,行基础护理,并对患者进行心理护理和健康宣教。结论上消化道出血的患者,病情严重,进展迅速,临床需及时准确地诊断,为患者实施积极的治疗和优质的护理,促进患者康复。