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121.
We present the first case of Holt-Oram syndrome associated with the lethal congenital heart defect of hypoplastic left heart syndrome. The possible pathophysiological link is explored and the need for careful genetic and cardiologic evaluation in these patients is reiterated. 相似文献
122.
以造影增强磁共振血管成像术诊断先天性主动脉弓畸形 总被引:1,自引:0,他引:1
目的评价造影增强磁共振血管成像术(CE-MRA)对先天性主动脉弓畸形的诊断准确性并与超声心动图等比较。方法413例先天性主动脉弓畸形病例在1999年4月到2004年12月期间做了CE-MRA检查。年龄5d~11岁,平均年龄2.4岁。检查使用1.5T磁共振扫描仪。对比剂gadolinium-DTPA,剂量0.2mmol/kg体质量,手动静脉注射。磁共振检查前均已做心脏超声检查。结果在413例中,动脉导管未闭(PDA)166例,主动脉缩窄(COA)168例,主动脉弓中断(IAA)31例,双主动脉弓等其他先天性主动脉弓畸形48例。全部413例均经手术和/或X线心血管造影证实。CE-MRA的诊断准确率为97.3%(402/413),心脏超声检查的诊断准确率为87.2%(360/413)。结论对于先天性主动脉弓畸形,CE-MRA是可靠的影像学检查方法,不仅优于心脏超声检查,有时CE-MRA甚至能比传统的X线心血管造影术提供更多的诊断信息。 相似文献
123.
Leukoerythrophagocytosis by sinus histiocytes in the lymph nodes is a rare cytological observation. Though often seen in lymph nodes draining malignancies, one may occasionally encounter them in vascular lesions. We report a case of leukoerythrophagocytosis by sinus histiocytes of the right supraclavicular lymph nodes in a 35-yr-old male. He presented with a painful soft tissue mass in the right anterior region of the chest wall extending into the axilla of 6 mo duration. Bilateral radial pulsations were absent. The patient had received treatment for pulmonary tuberculosis 1 yr ago. FNAC of the soft tissue mass revealed only blood. Radiological evaluation revealed a vascular lesion, with smooth borders, extending into the upper zone of right lung and displacing the second rib inferiorly. Doppler evaluation confirmed it to be a right subclavian aneurysm with arteritis. 相似文献
124.
H. L. Journée A. C. van Bruggen J. J. van der Meer A. B. de Jonge J. J. A. Mooij 《Medical & biological engineering & computing》1995,33(2):140-144
The recording of sounds over the oribt of the eye has been found to be useful in the detection of intracranial aneurysms.
A hydrophone for auscultation over the eye has been developed and is tested under controlled conditions. The tests consist
of measurement over the eyes in three healthy volunteers at rest, during voluntary breathing, during eyeball movements and
during sustained orbicular muscular contractions. Furthermore, measurements are performed at the side of the nose. Major features
of the hydrophonic transducer are high sensitivity to physiological sounds and a high degree of insensitivity to environmental
sounds propagated through the air. It can be concluded that the hydrophone may be useful for the early detection of intracranial
aneurysms and also for apnoea detection. 相似文献
125.
SCTA在微小脑动脉瘤诊断中的应用 总被引:3,自引:0,他引:3
目的 探讨螺旋CT血管造影(SCTA)在直径小于10mm的脑动脉瘤诊断中的临床应用和价值。方法 选择12例直径小于10mm的脑动脉瘤患,进行SCTA,DSA或MRA检查,SCTA成像技术为表面遮盖法(SSD)和最大密度投影法(MIP)。结果 12例微小脑动脉瘤患术前均准确定性,定位,全部经神经外科手术证实。结论 SCTA是一种无创伤性血管成像方法,在诊断脑动脉瘤方面,具有分辨率高,快速,准确,经济等优点,可为临床诊断与治疗提供更多的信息。 相似文献
126.
Histopathological characterization of aortic intimal sarcoma with multiple tumor emboli 总被引:2,自引:0,他引:2
Nishida N Yutani C Ishibashi-Ueda H Tsukamoto Y Ikeda Y Nakamura Y 《Pathology international》2000,50(11):923-927
A case of aortic intimal sarcoma with multiple tumor emboli and distal metastasis is reported. All metastasis (adrenal, spleen) were via the arteries. This case also had independent lung cancer. Macroscopically, the aortic tumor did not form a bulged mass, but had linear ulceration with abundant mural thrombi. Poorly cohesive large atypical cells were seen in the intima of the abdominal aorta without invasion into the media. Tumor cells were disseminated into the mural thrombi on the aorta and embolized its branches. In the metastatic tumor or tumor emboli of the distal artery, there were not only large atypical cells, but also the foci of spindle-shaped cells or epithelioid differentiation. Tumor cells in the aorta were immunohistochemically positive for only vimentin. Muscle-specific actin was positive focally for spindle-shaped cells of tumor emboli and metastatic tumors. Furthermore, cytokeratin-positive cells were scatteredly seen. All tumor cells were negative for factor VIII and did not have a histologic or phenotypic analogy with lung cancer. The primary intimal sarcoma in the present case was of undifferentiated non-endothelial intimal stromal cell origin, and may have had multipotential for differentiation. Investigation of the metastatic site was useful for recognizing the features of this tumor. 相似文献
127.
OLAV STOKLAND J
RGEN THORVALDSON ARNFINN ILEBEKK FREDRIK KIIL 《Acta physiologica (Oxford, England)》1983,117(4):481-489
To examine the factors contributing to the rise in systemic blood pressure during α- and β- adrenergic stimulation, phenylephrine, an α-adrenergic agonist, and norepinephrine, an α- and β-adrenergic agonist, were infused intravenously to anesthetized dogs until mean aortic blood pressure was raised equally by 40–60 mmHg. Changes in preload were estimated by changes in left ventricular end-diastolic pressure or segment length recorded by an ultrasonic technique. By obstructing the inferior vena cava (IVC), the increase in preload could be reduced to control level during phenylephrine and norepinephrine infusions without altering peripheral resistance (mean aortic blood pressure/cardiac output). Normalization of preload reduced the pressure response by 2/3 during phenylephrine infusion and by 1/4 during norepinephrine infusion. However, after β-adrenergic blockade by propranolol, normalization of preload reduced the pressure response by 2/3 during both phenylephrine and norepinephrine infusions. Thus, during α-adrenergic stimulation, the increase in preload is a more important factor than the increase in peripheral resistance. Norepinephrine raised stroke volume by 24±5%. When the increase in stroke volume was prevented by IVC obstruction, the pressure response to norepinephrine was halved. Thus, during norepinephrine infusion the rise in stroke volume caused by β-adrenergic stimulation is as important as α-adrenergic stimulation for the pressure response. 相似文献
128.
MICHÈLE COUTARD MARY OSBORNE-PELLEGRIN 《International journal of experimental pathology》1996,77(2):53-62
Microscopic aneurysmal-like structures (ALS) develop spontaneously in the convoluted rat testicular artery and have been previously proposed as a model relevant to cerebral aneurysms. The effect of defects in connective tissue fibres on ALS formation was investigated by microscopy using two approaches: (i) the study of the effect of β-aminopropionitrile (BAPN), an inhibitor of the cross-linking of elastic and collagen fibres, on the incidence, size and morphology of ALS in spontaneously hypertensive rats (SHR) and their normotensive controls (WKY). The straight spermatic artery was studied for comparison. (ii) The determination of the incidence of spontaneous ALS in Brown Norway (BN) and Long Evans (LE) rats which are highly susceptible (BN) or resistant (LE) to the spontaneous rupture of the arterial internal elastic lamina. (i) BAPN increased the number and size of ALS in SHR and WKY rats and had no effect on the straight spermatic artery and (ii) ALS were more numerous and of greater size in BN than in LE rats. Taken together, these results show that defective connective tissue fibres may favour the formation and induce the enlargement of aneurysmal-like structures. By analogy, these data suggest that a lack of connective tissue fibre integrity may be of importance in cerebral aneurysm formation and development. 相似文献
129.
本研究用螺旋CT扫描腹主动脉瘤获得的断层图像合成腹主动脉瘤几何模型,通过设定瘤壁组织生物力学参数和边界条件,使用有限元分析的方法分析腹主动脉瘤瘤壁的应力分布。结果标明,本例腹主动脉瘤应力峰值位于远端分叉部位,瘤体应力峰值位于后壁,均小于瘤壁的承受极限。本研究所得结果对腹主动脉瘤应力模型有助于分析个体化腹主动脉瘤的破裂部位和生长方向,对研究疾病进程提供依据。 相似文献
130.
目的探讨电解脱弹簧圈(Guglialm i detachab le coil,GDC)颅内动脉瘤栓塞术中动脉瘤再破裂的发生率、原因、对策及结果。方法302例颅内动脉瘤破裂患者行GDC栓塞术,其中8例发生术中动脉瘤再破裂。结果2例由微导丝穿破动脉瘤壁引起,3例由微导管穿破动脉瘤壁引起,2例由置放首枚弹簧圈时顶破动脉瘤壁引起,l例术中自发破裂,所有病例均继续行GDC动脉瘤填塞。2例死于动脉瘤破裂后大出血,其他6例均康复没有留下后遗症。本组术中动脉瘤再破裂发生率为2.6%,死亡率为25%。结论GDC血管内栓塞术中引起动脉瘤再破裂是十分少见的,但大部分病例经过继续填塞GDC可达到完全填塞动脉瘤,且不留下后遗症。 相似文献