Effect of auricular point pressing therapy on postoperative pain of fracture: A protocol for systematic review and meta-analysis

Background:In clinical practices, postoperative fracture patients are often treated with analgesics. As one of the alternative therapies for nondrug analgesia, auricular point pressing has advantages of simple operation, easy to use, no injury and adverse reactions, and great potential for development. In this study, the effect of auricular point pressing therapy on postoperative pain of fracture was objectively evaluated through the method of meta-analysis, so as to provide evidence for clinical applications.Methods:PubMed, Web of Science, Cochrane Library, EMBASE, Wan fang Database, Chinese Scientific Journal Database, China National Knowledge Infrastructure Database, and Chinese Biomedical Literature Database were systematically searched and randomized controlled trials on auricular point pressing in the treatment of postoperative pain after fracture were includes. After independent literature screening, data extraction and quality evaluation by 2 researchers, the original data was retrieved, merged, and analyzed. RevMan 5.3 software was adopted for meta-analysisResults:This study could provide high-quality evidence to evaluate the effect of auricular point pressing therapy on postoperative pain of fracture.Conclusion:This systematic review explored whether auricular point pressing therapy is effective on the intervention of postoperative pain after fracture.OSF Registration Number:DOI 10.17605/OSF.IO/AZ4JQ.     

The clinical efficacy of acupoint sticking combined with massage to treatment functional dyspepsia: A protocol of systematic review and meta-analysis

Background:The objective of this meta-analysis was to summarize and identify the available evidence from studies to estimate the clinical value of acupoint sticking combined with massage (ASM) in the treatment of functional dyspepsia (FD), and provide clinicians with evidence on which to base their clinical decision making.Methods:This review will include all studies comparing clinical efficacy of ASM in the treatment of FD. The search strategy will be performed in 10 databases. We will not establish any limitations to language and publication status, published from inception to the August 2020. Two reviewers will screen, select studies, extract data, and assess quality independently. Outcome is alleviation of global dyspeptic symptoms, alleviation of individual dyspeptic symptoms, quality-of-life improvement, and safety. The methodological quality including the risk of bias of the included studies will be evaluated. We will carry out statistical analysis using RevMan 5.3 software.Results:This study will summarize current evidence to assess the efficacy and safety of ASM in the treatment of FD.Conclusion:The findings of this study will provide helpful evidence for the clinician, and will promote further studies, as well as studying the value of ASM.Registration number:INPLASY2020110072 (DOI number: 10.37766/inplasy2020.11.0072).     

经皮穴位电刺激对反复着床失败冻融胚胎移植患者的影响

目的观察经皮穴位电刺激(transcutaneous electrical acupoint stimulation,TEAS)对胚胎移植后反复着床失败的患者冻融胚胎移植周期子宫内膜、妊娠结局的影响。方法将176例反复着床失败行冻融胚移植的患者随机化分为两组:观察组82例:常规冻胚移植前内膜准备,月经第10天起给予TEAS;对照组94例:常规冻融胚移植前内膜准备,不予其他干预措施。比较两组患者移植前与月经第10天内膜增厚差值、生化妊娠率、临床妊娠率、胚胎着床率的差异。结果观察组生化妊娠率大于对照组,但差异无统计学意义;观察组内膜生长差值、着床率、临床妊娠率均大于对照组,且差异有统计学意义(P0.05)。结论 TEAS可提高反复着床失败患者的子宫内膜容受性,提高此类患者冻融胚移植成功率。     

结合恶性胸腔积液中脱落细胞探讨上皮细胞-间质转化与非小细胞肺癌的相关性

目的探讨恶性胸腔积液(malignant pleural effusion,MPE)中非小细胞肺癌(non-small cell lung cancer,NSCLC)上皮细胞-间质转化(epithelial-mesenchymal transition,EMT)相关分子标志物的表达及意义。方法对823例胸水标本进行液基细胞薄层检测(thinPrep cytology test,TCT),结合活检结果确诊107例NSCLC标本,随机分成NSCLC细胞组、NSCLC活检组及NSCLC癌旁组织组三组,对其中39例NSCLC细胞组胸水标本进行沉渣后包埋、切片,采用免疫组化SP法检测三组中vimentin、E-cadherin、N-cadherin、β-catentin的表达,并进行对比分析。结果E-cadherin、β-catentin阳性/异常阳性率在NSCLC细胞组、活检组均明显低于癌旁组织组(P<0.05)。NSCLC细胞组、活检组N-cadherin、vimentin的阳性率均明显高于癌旁组织组(P<0.05)。同时亦发现,在NSCLC细胞组中,E-cadherin表达与分化程度和淋巴结转移有关(P<0.05),β-catentin异常阳性与分化程度有关(P<0.05),N-cadherin与vimentin表达与淋巴结转移有关(P<0.05)。以上4个抗体表达/异常表达均与患者年龄、性别、吸烟史和组织学分型无关(P>0.05)。结论MPE中NSCLC细胞具备EMT表型,从细胞学角度进一步证实EMT现象存在于NSCLC,为新的靶向治疗药物的研究和治疗靶点提供新思路。     

音乐疗法联合针刺与耳穴按压在初产妇分娩中的应用

目的探讨音乐疗法联合针刺与耳穴按压在初产妇分娩中的效果。方法采用便利抽样法,选取2017年6—12月于浙江大学舟山医院产科分娩的初产妇90例为研究对象,按随机数字表法分为干预组和对照组各45例。对照组采用音乐疗法,收听患者自己喜欢的音乐,干预组在对照组基础上采用针刺与耳穴按压。比较两组产妇的疼痛数字评分(NRS)、宫口开3~10 cm的时间、新生儿阿普加评分及产后2 h出血量。结果在宫口开≥3 cm时,两组初产妇NRS评分比较差异无统计学意义(P>0.05);镇痛后30 min和宫口开全时,干预组的NRS评分均低于对照组,两组比较差异有统计学意义(P<0.05)。干预组患者宫口开3~10 cm的时间短于对照组,两组比较差异有统计学意义(P<0.05)。两组患者的新生儿阿普加评分、产后2 h出血量比较,差异无统计学意义(P>0.05)。结论在音乐疗法的基础上联合针刺与耳穴按压能减轻分娩疼痛,缩短宫口开全时间,且对母婴安全,效果优于单纯音乐疗法,值得推广应用。     

丁桂儿脐贴穴位敷贴预防经尿道前列腺电切术后膀胱痉挛的效果观察

目的探讨丁桂儿脐贴穴位敷贴联合电切灌洗液冲洗在预防经尿道前列腺电切术(TURP)术后膀胱痉挛中的应用效果。方法80例行TURP治疗的患者随机分为观察组和对照组,各40例。对照组于术中、术后采取(35.50±1.50)℃电切灌洗液持续冲洗,观察组在对照组基础上在围术期采用丁桂儿脐贴进行穴位敷贴。观察2组术后膀胱痉挛发生情况。结果观察组术后膀胱痉挛发生率7.50%(3/40),低于对照组25.00%(10/40),差异有统计学意义(P<0.05)。结论丁桂儿脐贴穴位敷贴联合电切灌洗液冲洗能有效预防TURP术后膀胱痉挛。     

隔姜灸联合中药穴位贴敷辅助治疗脾胃虚寒型胃脘痛的效果及护理

目的观察隔姜灸联合中药穴位贴敷辅助治疗脾胃虚寒型胃脘痛中的效果,总结护理措施。方法将50例脾胃虚寒型胃脘痛患者随机分为对照组和观察组,各25例。对照组给予常规治疗和护理,观察组在对照组基础上给予隔姜灸联合中药穴位贴敷干预。对比2组临床疗效。结果观察组治疗有效率96.00%(24/25),高于对照组的76.00%(19/25),差异有统计学意义(P<0.05)。结论隔姜灸联合中药穴位贴敷治疗脾胃虚寒型胃脘痛能有效改善患者临床症状,对提高治疗效果有积极作用。     

穴位注射在眼科的应用

摘要：穴位注射是以中医基础理论为指导,将药物注入穴位,通过经络循行激发人体气血,恢复正气的一种治疗方法。药物、穴位、经络三者相互作用于机体,从而达到更好的预防、治疗、改善的目的。因其操作简便、高效安全被常用于眼科疾病治疗,穴位注射在眼科方面,为一些疑难眼病的治疗提供了有效的治疗方法,药物可以高效直接地作用于眼部穴位,改善眼部微循环,穴位注射可以治疗眼表疾病和内障眼病,以及眼科一些围手术期或加快手术治疗后恢复的过程,同时也为治疗视网膜及视神经病变等疾病的治疗提供新的中西医结合的有效思路,具有简便廉验的优点,应该临床推广。