从《四部医典》看汉、藏医德学之渊源

《四部医典》是藏医学发展史上最伟大的成果之一,它辩证地吸收了汉、藏医学著作的精华,总结了藏医药的临床经验,与中医学有着密切的源流关系。其对医德学的论述与中医医德学思想之间也有着紧密的渊源关系,唐蕃和亲及文化交流和吐蕃统治者对医学发展的重视是二者渊源关系存在的主导性因素。     

四川凉山20-30岁彝族人群指长与身高的相关性研究

目的研究四川凉山彝族人群指长与身高的相关关系。方法按照人体骨骼测量方法,测量208例(男151,女57)20-30岁四川彝族健康成年人左手五指长度、五指末端指节长度及身高。结果与结论男性左手10个测量指标与身高均有显著相关性,其中中指长与身高相关性最大(r=0.372)。女性只有食指长、中指长、环指长、小指长及食指末节长与身高有显著相关性,以食指末节长与身高的相关性最大(r=0.454)。     

Allele frequencies of mitochondrial D-loop (CA)n repeat polymorphism in six Chinese ethnic groups

Allele frequencies of mitochondrial D-loop (CA)(n) repeat was carried out in six Chinese ethnic groups: Han ethnic group in Beijing, Uygur ethnic group in Kashi of Xinjiang province, Li ethnic group in Hainan province, Yao ethnic group in Junan of Guangxi province, Tibet ethnic group in Lasa of Xizang province and Yi ethnic group in Honghe of Yunnan province. A total of 542 individuals were typed. Comparative analyses between our population data and other populations gathered from the literature were performed.     

Hepatoprotective effects of Yi Guan Jian, an herbal medicine, in rats with dimethylnitrosamine-induced liver fibrosis

Aims of the study

Yi Guan Jian (YGJ) has long been employed clinically to treat liver fibrosis in traditional Chinese Medicine but the mechanism underlying the regulation has not been clarified in detail. The present investigation was designed to assess the involvement of the fibrosis pathway in dimethylnitrosamine (DMN)-induced liver fibrosis in rats.

Materials and methods

Liver fibrosis was induced by DMN injection (10 mg/kg, i.p., given three consecutive days each week) following 4 weeks. YGJ was oral administered (1.8 g/kg daily via gastrogavage for two weeks). Liver sample were subjected to histological and western blot studies. For evaluation of hepatic fibrosis-related factors, collagen α1-I, tissue inhibitor of metalloproteinase-1 (TIMP-1), and α-smooth muscle actin (α-SMA) mRNA and protein levels were analyzed.

Results

YGJ remarkably prevented body weight loss and DMN damage in the liver, and it inhibited the elevation of serum glutamate oxaloacetate transaminase (GOT), and glutamic pyruvic transaminase (GPT). Oral administration of YGJ extract significantly reduced the accumulation of collagen α1-I, TIMP-1, and α-SMA in liver tissues.

Conclusions

Taken together, these findings indicate that the YGJ Chinese herb showed hepatoprotective and anti-fibrogenic effects against DMN-induced hepatic injury. Our data suggest that the YGJ may be useful in reversing the development of hepatic fibrosis.     

补肾益脑汤治疗脑梗死的实验研究

目的探讨中药补肾益脑汤对实验性脑梗死大鼠脑细胞保护的作用机理。方法用线栓法制作大鼠大脑中动脉阻断（MCAO）模型,具有脑梗死临床特征者为脑梗死大鼠模型,共50只。对模型随机分为模型组、对照组、治疗高剂量组、治疗低剂量组各10只,同时设正常对照组10只,用药30天后取出大脑,观察梗塞灶周围脑组织中bFGF及VEGF表达情况。结果通过治疗实验性脑梗死大鼠的观察,该药对脑细胞保护已能达到治疗目的。结论补肾益脑汤对实验性脑梗死大鼠有治疗作用。     

作为隐性知识的中医及其策略

波兰尼认为,在柏拉图的显性知识传统之外,存在着只可意会不可言传的隐性知识。就知识的个人性、默会性和寄托而言,中医知识的大部分完全符合波兰尼关于隐性知识的标准。“医者意也,意者医也”,可以说,中医作为一种知识其神韵正在于它的“可以意会,难于言传”的特性。这种特性决定了中医应当有着不同于西医的知识产权策略、知识交流策略和人才策略。     

益宫颗粒联合抗生素用于药流后出血临床效果观察

目的探讨益宫颗粒联合抗生素治疗药流后阴道出血的临床效果。方法随机选择400例早孕行药流的健康女性进行对照试验,其中研究组（益宫颗粒联合抗生素治疗）200例,对照组（单纯抗生素治疗）200例。1个疗程均为7天,观察流产后阴道流血止血时间以及第一次月经复潮时间等。结果两组阴道出血时间、出血量P〈0.05有显著性差异,第一次月经复潮时间P〈0.05有显著性差异,清宫率P〉0.05无显著性差异。本研究中各组均未发生不良反应。结论益宫颗粒联合抗生素可以减少药流后出血时间,促进子宫复旧,药物安全性良好,值得临床推广应用。     

云南临沧云县地区彝族胃幽门螺杆菌感染的危险因素分析

对云南临沧云县地区４６６名彝族自然人群ＨＰ感染情况及其危险因素分析。通过Ｌｏｇｉｓｔｉｃ多因素分析和卡方检验单因素分析，结果发现：云县地区彝族的ＨＰ感染率为５３．０％；ＨＰ感染率随年龄增长而增加；多因素Ｌｏｇｉｓｔｉｃ分析筛选出的主要危险因素是饮水习惯、饮用水源、家庭胃癌史、吸毒和养猪；大蒜是重要保护因素。单因素卡方检验筛选出的有关联因素为饮水习惯、上消化道症状，使用抗生素、养鸡、家庭胃癌史、饮用水源、家庭溃疡史、中药、养狗和吸毒。     

Traditional Chinese medicine "Qing Yi Tang" alleviates oxygen free radical injury in acute necrotizing pancreatitis

AIM To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine "Qing Yi Tang" in acute necrotizing pancreatitis (ANP).METHODS After induction of ANP by injection of sodium taurocholate into pancreatic duct, 16 dogs were randomly divided into control group and Chinese medicine group. Serum amylase, SOD and MDA were determined on postoperative day 1, 2, 4 and 7. The animals were sacrificed on day 7. SOD and MDA in organs were determined, and pathological changes in pancreas were observed.RESULTS As compared with control group, the serum level of amylase (734U/L vs 2783U/L) and MDA (7.8nmol/ml vs 14.8nmol/ml) in Chinese medicine group were decreased on day 7 (P＜0.05), while SOD increased significantly (281nU/ml vs 55nU/ml, P＜0.01), and similar changes occurred in MDA and SOD in organs, especially in the pancreas; the pathological changes in the pancreas were alleviated as well.CONCLUSION "Qing Yi Tang" is effective in clearing OFRs and alleviating pathological changes in ANP.