基于CiteSpace可视化分析气虚血瘀证研究热点趋势＊

目的 基于CiteSpace分析近20年“气虚血瘀证”的研究，探索其研究现状和热点趋势。方法 收集中国知网（CNKI）数据库2001年至2021年气虚血瘀证相关文献，用CiteSpace知识图谱直观展示对发文量、作者、机构、关键词等信息进行分析。结果 共纳入文献1955篇。发文量显示，气虚血瘀证发文量呈现上升趋势。作者和机构分析发现以北京中医药大学王伟团队、中国中医科学院刘建勋团队等是研究气虚血瘀证的核心团队。关键词分析提示研究方向主要在气虚血瘀证疾病证候分类、中医药临床治疗、研究的方法学和发生机制等方面。结论 本研究利用知识图谱直观展示了近20年气虚血瘀证的研究进展和热点趋势，以期为气虚血瘀证的研究前沿提供新的视角参考。     

Visualizing risks in cancer communication: A systematic review of computer-supported visual aids

ObjectiveHealth websites are becoming important sources for cancer information. Lay users, patients and carers seek support for critical decisions, but they are prone to common biases when quantitative information is presented. Graphical representations of risk data can facilitate comprehension, and interactive visualizations are popular. This review summarizes the evidence on computer-supported graphs that present risk data and their effects on various measures.MethodsThe systematic literature search was conducted in several databases, including MEDLINE, EMBASE and CINAHL. Only studies with a controlled design were included. Relevant publications were carefully selected and critically appraised by two reviewers.ResultsThirteen studies were included. Ten studies evaluated static graphs and three dynamic formats. Most decision scenarios were hypothetical. Static graphs could improve accuracy, comprehension, and behavioural intention. But the results were heterogeneous and inconsistent among the studies. Dynamic formats were not superior or even impaired performance compared to static formats.ConclusionsStatic graphs show promising but inconsistent results, while research on dynamic visualizations is scarce and must be interpreted cautiously due to methodical limitations.Practice implicationsWell-designed and context-specific static graphs can support web-based cancer risk communication in particular populations. The application of dynamic formats cannot be recommended and needs further research.     

应用MedlineR挖掘基因间关系的尝试

应用MedlineR对Medline文献数据库中基因之间关系进行挖掘,并应用Pajek实现挖掘结果的可视化.实践证明MedlineR可以帮助医学科研人员对感兴趣的论题形成假设,得到相关因素的可视化图谱,是建立更加复杂的文献数据挖掘应用的基础,也是对实验方法的重要补充.     

3D-visualization of the temporomandibular joint with focus on the articular disc based on clinical T1-, T2-, and proton density weighted MR images

Objective An approach of 3D-visualization of the temporomandibular joint (TMJ) with special focus on the articular disc based on magnetic resonance imaging (MRI) was developed for the purpose of diagnosis support. Materials and methods Mandibular condyle and fossa were reconstructed as 3D-surfaces. Articular disc, retrocondylar tissue, and the lateral pterygoid muscle were visualized by means of direct volume rendering. By simultaneous visualization of both, the bony surfaces and the soft tissue, anterior disc displacement could be recognized in 3D-context. Additional superposition of the 3D-visualization with the original 2D-MRI slices allowed for a combination with conventional diagnostics. The method was tested for clinical T1-, T2-, and proton density weighted MRI data from four independent medical institutions. Results For all cases, the skeletal anatomy could be reproduced. Applied validation approaches showed good results. Anterior disc displacement could be clearly depicted as well as the incidence of reduction of the disc. By several experienced observers, the approach was rated as significant. Conclusion Although partially non-standard in the clinical routine the new method provided promising results for efficient diagnosis support. Its validity in the medical practice, namely, its impact for dislocation/deformity of the mandibular disc will be further analyzed. This paper has been written on behalf of a publication request following Cars 2006 conference held in June 2006 in Osaka, Japan. The title of the talk at Cars 2006 conference was “An approach for three-dimensional rendering of the mandibular disc based on high-resolution MR images” authored by Kober C, Hayakawa Y, Kinzinger G, Yamamoto M, Sano T, Sader R, see Int J Comput Assist Radiol Surg 2006 1(Suppl 1): 405–406. I apologize for the delay which was caused by very dense time schedule. In return, the article is a considerable extension of the work presented at Cars 2006.     

Compositional and functional alterations of gut microbiota in patients with stroke

Background and aimsThere is accumulating evidence that gut microbiota plays a key role in cardiovascular diseases. Gut bacteria can transform dietary choline, l-carnitine, and trimethylamine N-oxide (TMAO) into trimethylamine, which can be oxidized into TMAO again in the liver. However, the alterations of the gut microbiota in large artery atherosclerotic (LAA) stroke and cardioembolic (CE) stroke have been less studied.Methods and resultsWe performed a case–control study in patients with LAA and CE types of strokes. We profiled the gut microbiome using Illumina sequencing of the 16S ribosomal RNA gene (V4–V5 regions), and TMAO was determined via liquid chromatography–tandem mass spectrometry. Our results showed that the TMAO levels in the plasma of patients with LAA and CE strokes were significantly higher than those in controls (LAA stroke, 2931 ± 456.4 ng/mL; CE stroke, 4220 ± 577.6 ng/mL; healthy control, 1663 ± 117.8 ng/mL; adjusted p < 0.05). The TMAO level in the plasma of patients with LAA stroke was positively correlated with the carotid plaque area (rho = 0.333, 95% CI = 0.08–0.55, p = 0.0093). Notably, the composition and the function of gut microbiota in the LAA stroke group were significantly different from those in the control group (FDR-adjusted p-value < 0.05). There was no significant association between gut microbiota and CE stroke in our study.ConclusionThis study provides evidence for significant compositional and functional alterations of the gut microbiome in patients with LAA stroke. Gut microbiota might serve as a potential biomarker for patients with LAA stroke.     

基于CiteSpace的国际医学图书馆研究可视化分析

借助CiteSpace分析软件及Web of Knowledge网站分析功能,绘制国际医学图书馆研究领域科学知识图谱,探讨近10年来国际上对医学图书馆的研究现状,了解其核心作者、国家机构和期刊分布情况,揭示其研究热点和前沿领域,为医学图书馆实际工作的开展提供参考。     

基于Gephi的云南民族医药研究可视化分析

采用文献计量法、社会网络可视化分析工具Gephi对云南民族医药研究情况从发文年代、期刊分布、作者分布、合著网络、研究机构分布、关键词共现网络等方面进行分析,指出傣医、傣药为该领域研究的热点。     

我国阅读推广研究的可视化分析

以中国知网收录的CSSCI文献为数据源,采用信息计量、可视化展示和内容分析等方法,从文献量年度分布、核心作者与机构共现网络等方面揭示我国阅读推广研究的分布特征,以知识图谱的形式展示了其发展脉络两个阶段的研究热点,简要评价了其研究内容,以期为促进阅读推广理论和实践的创新发展提供借鉴和参考。     

俯卧位摄影在排泄性尿路造影中的应用

目的完善造影中的摄影体位,显示最佳的造影效果。方法对50例泌尿系梗阻伴积水患者,在IVP中采取先传统仰卧位,必要时俯卧位的造影方法,对其先后两种方法的显影效果进行比较。结果先仰卧位再俯卧位摄影后,肾盂肾盏显影率提高20%,P<0.05;肾盂-输尿管连接部及各段显影率提高18%,P<0.05。结论排泄性尿路造影,必要时采取俯卧位摄影,能弥补传统造影体位的不足,使梗阻部位在仰卧前后位无法显示的解剖机构和病变满意显示出来,是泌尿系梗阻时,肾盂肾盏及解压后输尿管全程显影最好的补充体位。方法简便,值得常规鉴用。