紫外线消毒灯的转动装置

利用紫外线进行消毒，投入少、使用方便、效果可靠。紫外线可以杀灭各种微生物。但是紫外线辐照能量低，穿透力弱，仅能杀灭直接照射到的生物。由于紫外线消毒灯所照射只是一个固定的方向，所以对大面积的消毒有一定的死角，影响消毒的质量。为了克服现有紫外线灯消毒技术中的缺点，本实用新型（专利号：200420042508X）的目的是在紫外线消毒灯原有的基础上增设通风器，促使室内空气流通速度加快。利用转动紫外线灯座改变紫外线直射方向，扩大直射的范围，达到增强消毒效果。     

两种空气消毒方法对接台手术室空气消毒效果的比较

目的比较紫外线灯照射和独立单元空气净化系统两种方法对接台手术室空气的消毒效果,探讨无层流装置手术间的接台手术室空气消毒方法. 方法用平板自然沉降法于手术室空气开始消毒前及消毒后不同时段采样检测,观察两种方法对接台手术室空气中自然菌的杀灭效果. 结果在保证接台手术合理时间间隔的前提下,两种方法均能使术前空气中自然菌的消除率达到80%;利用紫外线消毒,在人员进入手术室后空气中菌落数明显上升;空气净化可以在人在条件下对手术室空气进行持续消毒杀菌,使手术全过程空气中平均菌落数达到国家标准. 结论独立单元空气净化系统可以缩短手术间隔时间,并且是解决接台手术人在条件下持续空气消毒的较好方法.     

含马兜铃酸类中药材中马兜铃总酸的含量

目的：建立马兜铃总酸的含量测定方法，并测定不同地区市售青术香及其它八种含马兜铃酸类中药中马兜铃总酸的含量，用于指导临床安全、合理用药。方法：用紫外分光光度法分析，检测波长为390nm。结果：马兜铃酸A在0．047。0．235mg范围内（r=0．9992）有良好的线性关系；平均加样回收率为98．16％，RSD=2．04％。不同地区市售青木香中马兜铃总酸含量在0．145％～0．567％范围内，其中以河北安国含量最高（0．567％），重庆含量最低（0．145％）；八种含马兜铃酸类中药材中马兜铃总酸含量在0．178％～0．717％范围内，其中以关木通含量最高（0．717％），华细辛含量最低（0．178％）。结论：本方法简便、准确，可用来测定其它含有马兜铃酸类中药材及中成药中马兜铃总酸的含量。     

急诊中毒快速检验诊断系统的建立

目的建立急诊中毒的快速检验诊断系统。方法运用中毒诊断专家系统、可见紫外分光光度计、气相色谱仪、薄层色谱扫描仪、气相色谱质谱联用仪、原子吸收光谱仪、动物实验和毒品金标筛选试剂盒建立急诊中毒快速检验诊断系统。结果酒精和一氧化碳中毒检验诊断可在20min内完成,诊断准确度达100%。其他中毒检验诊断可在0.5￣2h内完成。太原地区急诊中毒出现顺序为:安眠镇静药类>乙醇>一氧化碳>其他临床药物>杀虫剂>鼠药>亚硝酸盐>毒品。山西省内中毒死亡原因为一氧化碳>毒鼠强>杀虫剂。结论本研究建立的急诊中毒快速检验诊断系统具有快速、简便、准确、适用面广的特点,可应用于急诊中毒的快速检验诊断。     

紫外分光光度法测定注射用甘氨双唑钠的含量

【目的】采用紫外分光光度法测定注射用甘氨双唑钠的含量。【方法】采用紫外分光光度法在319nm处测定甘氨双唑钠的含量，8h内考察其稳定性。【结果】甘氨双唑钠在5．5～27．5μg／ml浓度范围内与吸收度呈良好线性关系（r=0．9999），在8h内稳定性良好，平均回收率为100．4％，RSD为1．93％（n=9）。【结论】用紫外分光光度法测定注射用甘氨双唑钠的含量操作简便，结果准确。     

LONG TERM SUPPLEMENTATION OF SE-ENRICHED MALT FOR THE HIGH RISK POPULATION OF LUNG CANCER: INHIBITION OF ULTRAVIOLET LIGHT AND BENZOaPYRENE INDUCED UNSCHEDULED AND SYNTHESIS OF PERIPHERAL LYMPHOCYTES

Se malt cakes containing 300μg selenium were taken up daily to men from high risk area in lung cancer and the influences of Ultraviolet (UV) and Benaopyrene (BαP) induced unscheduled DNA synthesis (UDS) were determined. The Se levels in serum, hair and activity of GSH-px were increased by 89%, 67% and 178%, respectively, after Se-supplementation for half year. In the UV treatment, the ratio of UDS was decreased from the mean values of 2. 47 in the control to 1. 61 (P<0. 05) in the Se-group, In the BaP treatment, furthermore, the elevated Se levels of 78% in serum and 83% in the hair accompanied with 56% high in activity of GSH-px were followed by the Se intake for one year, while the mean value of UDS was reduced from 2. 21 in the control to 1. 47(P< 0. 05) in the group of selenium tested. The blocking effects of UV irradiation and BaP treatment induced UDS of peripheral lymphocytes were showed in the Se-supplementation.     

维生素E、C对紫外线辐射致皮肤细胞氧化性损伤的保护作用

以丙二醛（MDA）为指标,观察小鼠皮肤细胞体外经紫外线照射后脂质过氧化水平的变化。结果表明:小鼠皮肤细胞中的MDA含量随照射时间的延长而增加;同时观察了用VE和VC作保护剂,以同样的照射条件处理小鼠皮肤细胞后,MDA含量明显低于非保护组（P＜0.01）。结果说明紫外线对小鼠皮肤细胞具有一定的氧化毒性,维生素E、C具有抗紫外线所致的氧化性损伤的作用。     

Repair of DNA damage in light sensitive human skin diseases

Summary Repair of UV-light induced DNA damage and changes in the semiconservative DNA synthesis were studied by in vitro autoradiography in the skin of patients with lightdermatoses (polymorphous light eruption, porphyria cutanea tarda, erythropoietic protoporphyria) and xeroderma pigmentosum as well as in that of healthy controls. In polymorphous light eruption the semiconservative DNA replication rate was more intensive in the area of the skin lesions and in the repeated phototest site, the excision repair synthesis appeared to be unaltered. In cutaneous porphyrias a decreased rate of the repair incorporation could be detected. Xeroderma pigmentosum was characterized by a strongly reduced repair synthesis.     

The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity

An RNA-binding protein, the Ro 60 kDa autoantigen, is a major target of the immune response in patients suffering from two systemic rheumatic diseases, systemic lupus erythematosus and Sjogrens syndrome. In lupus patients, anti-Ro antibodies are associated with photosensitive skin lesions and with neonatal lupus, a syndrome in which mothers with anti-Ro antibodies give birth to children with photosensitive skin lesions and a cardiac conduction defect, third degree heart block. In vertebrate cells, the Ro protein binds small RNAs of unknown function known as Y RNAs. Although the cellular function of Ro has long been mysterious, recent studies have implicated Ro in two distinct processes: small RNA quality control and the enhancement of cell survival following exposure to ultraviolet irradiation. Most interestingly, mice lacking the Ro protein develop an autoimmune syndrome that shares some features with systemic lupus erythematosus in patients, suggesting that the normal function of Ro may be important for the prevention of this autoimmune disease. In this review, we summarize recent progress towards understanding the role of the Ro 60 kDa protein and discuss whether the cellular function of Ro could be related to certain manifestations of lupus in patients.Abbreviations RNP Ribonucleoprotein - RRM RNA recognition motif - SCLE Subacute cutaneous lupus erythematosus - SLE Systemic lupus erythematosus - snRNP Small nuclear ribonucleoprotein - SS Sjogrens syndrome - UV Ultraviolet - VWFA von Willebrand factor A     

Study of the ultraviolet emission of the electrode coatings of arc welding

The optical emission properties of several minerals components employed in electrode coatings of arc welding have been investigated. The X-ray diffraction analysis shows that the composition of 14 commercial electrode coatings collected from different countries (Spain, France, UK, Poland, Argentina and Germany), consists of quartz, calcite, sodium and potassium rich feldspars, muscovite and rutile. The natural thermal stimulated luminescence (TSL) of these mineral phases, measured in the range of 200-800 nm at different temperatures (from room temperature to 400 degrees C) displays UV-A (wavelengths of 320 nm to 400 nm) and UV-B (from 280 nm to 320 nm) emissions, with the exception of rutile. The UV-B radiation, commonly described as the most dangerous form of radiation to human life, is here associated with structural defects in the crystallographic lattice of the mineral components of electrode coatings.