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益气活血化痰法对血管性痴呆大鼠脑组织中内皮素和降钙素相关基因肽的影响 总被引:5,自引:0,他引:5
目的 :通过对VD大鼠脑组织ET 1和CGRP含量的测定 ,探讨其在VD形成过程中的发病机制和中药干预机制。方法 :采用放射免疫分析法测定脑组织ET 1和CGRP浓度。结果 :1 模型组、正常组与假手术组比较ET 1含量升高 ,CGRP含量降低 ,均有非常显著性差异 (P <0 0 1) ;2 大剂量组ET 1含量变化较治疗前明显降低 ,CGRP含量较治疗前明显升高 ,均有非常显著性差异 (P <0 0 1)。讨论 :VD在形成过程中ET 1含量增高 ,CGRP含量降低 ,失去二者的平衡 ,中药能有效调节二者的平衡 ,是防治VD的可能机制之一。 相似文献
43.
王檀教授认为,哮病具有迁延难治且反复发作的特点,在北方严寒之地其发病率更为突出.引起哮病发作的原因错综复杂,其病因无外乎外感及内因.提出"哮病主于火"及"五脏六腑皆令人哮"为哮病的病机关键.从脏腑相干理论出发提出哮病因火、热而哮,因痰而作.治疗时,当辨清五脏六腑的寒热虚实,调整脏腑功能,尤其脾胃的功能的健运.从火、热论治哮病,发则治其标,缓则治其本. 相似文献
44.
钟荣光 《中国医疗器械信息》2020,(7):173-174,176
低温等离子灭菌器是医院消毒供应中心一种较为常见的医疗设备,其工作原理主要是利用过氧化氢在极度真空的灭菌舱环境中汽化后均匀扩散到整个空间,再由高频电压产生高频电场使得过氧化氢气体形成等离子体体系,多个因子间共同起到杀菌的效果。灭菌处理的全部过程均是在干燥的低温情况下进行,所以基本不会对医疗器械产生破坏作用,且不会残留任何毒性,因此其在金属与非金属的灭菌处理中均可使用。本院使用山东新华PS-100低温等离子灭菌器,为医疗器械灭菌消毒工作提供了诸多便利,但使用期间曾出现真空期超时、提纯器温度太低、扩散期压力太低、线路等故障,现就其检修过程进行分析,以供参考。 相似文献
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PURPOSE: To examine the influence of tan preference and skin type on sun protection behaviors of Australian adolescents. METHODS: The Australian Secondary School Alcohol and Drug Questionnaires were conducted in 1993, 1996, 1999 and 2002 among randomly selected students aged 12--17. Schools were randomly selected from each education sector in each state. The self-administered questionnaire contained questions about tan preferences, skin type and usual SunSmart behavior (use of sunscreen, hats and covering clothing). RESULTS: The routine use of SunSmart behavior was low in all survey years. There was a significant decrease over time in the proportion of students who practiced SunSmart behavior, with prevalence rates lower in 2002 than in any other survey year (males: p<0.01 and females: p<0.01). As desire for a tan increased, routine practice of SunSmart behaviors decreased. Across the four survey periods, male (p<0.01) and female (p<0.01) students who preferred no tan were significantly more likely to practice SunSmart behavior than students who preferred any sort of tan. Across the four survey years, male (p<0.01) and female (p<0.01) students with skin that 'just burns' were most likely to routinely practice SunSmart behavior. CONCLUSIONS: Sun protection practices among adolescents have continued to decline significantly over time. Future educational programs require an innovative approach to modify adolescent behaviors in relation to sun exposure and sun protection. 相似文献
47.
Guanghua Liu Qiang Ouyang Fang Xia Guoping Fan Juming Yu Caiyuan Zhang Dengbin Wang 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2019,21(1):107-113
Background
To investigate the clinical value of the alpha-fetoprotein (AFP) response following transcatheter arterial chemoembolization (TACE) in intermediate-stage hepatocellular carcinoma (HCC).Methods
Data on patients with Barcelona Clinic Liver Cancer B staging system were analyzed. An AFP response was defined as a decrease in AFP of more than 20% after a TACE session. The association between AFP response and treatment outcome regarding imaging response and overall survival (OS) was explored. Cox proportional hazards models were applied to identify independent risk factors for OS after TACE.Results
Of the enrolled 376 patients with elevated serum AFP >20 ng/mL, 214 (57%) with AFP responses were identified. AFP responders had improved median survival than non-responders (20 vs. 12 months, P = 0.002). AFP response was significantly correlated with imaging response (P < 0.001). The Cox proportional hazards model revealed that AFP response was an independent factor for OS (hazard ratio, 0.59; 95% confidence interval, 0.45–0.78; P < 0.001). In stratified analyses, an AFP response achieved improved survival in patients with tumor diameters ≤5 cm, diameters >5 cm, tumor number ≤3 and without underlying cirrhosis.Conclusions
The AFP response indicates enhanced survival after TACE in patients with intermediate-stage BCLC. 相似文献48.
Ka W. Ma Tan T. Cheung Wong H. She Kenneth S.H. Chok Albert C. Yan Chan Jeff W. Chiu Dai Chung M. Lo 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2018,20(11):1067-1072
Background
Recurrent pyogenic cholangitis (RPC) is a known risk factor for intrahepatic cholangiocarcinoma (ICC), whether it represents a poor prognostic factor remains controversial. The aim of this study was to investigate the post-hepatectomy oncological outcomes of patients with ICC and coexisting RPC.Method
A retrospective analysis with propensity score matching (PSM) was performed for comparison between ICC patient with and without RPC.Results
There were 143 patients with ICC with a median follow-up of 21 months. RPC was diagnosed in 18% of patients. The time from RPC diagnosis to ICC diagnosis was 137(47–481) months. The 3-year disease-free (DFS) and overall survival for the whole population was 34% and 43% respectively. Preoperative child score, elevated carcinoembryonic antigen, presence of microvascular invasion, multiple tumours, presence of postoperative complications and RPC were independent factors for DFS and OS. After PSM, 60 ICC patients who did not have RPC were compared with 20 ICC patients with RPC. Patients with RPC had significantly worse median DFS (10 vs 23 months, P = 0.020) and OS (15 vs 45 months, P = 0.004) when compared to the patients without RPC.Conclusion
RPC represents a poor prognostic factor affecting outcomes after hepatectomy for patients with ICC. 相似文献49.
谭新华工作室无子(男性不育症)中医诊疗方案 总被引:2,自引:0,他引:2
夫妇婚后同居1年以上,有正常规律的性生活,未采用任何避孕措施,由于男方原因,造成女方不能受孕,或能使女方受孕但不能成功分娩者称为男性不育症.男性不育症不是一个独立的疾病,是由一种或多种疾病因素、理化因素及不良生活方式作用于生殖众多环节后导致的一种病证.本症临床上可分为绝对性不育、相对性不育、原发性不育、继发性不育4种类型.本病属于中医学“无子”、“无嗣”、“男子艰嗣”范畴. 相似文献
50.