“偏瘫宁”制剂及其临床应用

目的：观察中西药配伍合剂“偏瘫宁”治疗缺血性脑血管病的临床疗效。方法：对300例缺血性脑血管病患者进行了“偏瘫宁”疗效观察，并与采用脉通治疗的30例结果对比，结果：临床症状和肌力恢复程度，治疗后有明显改善，总有效率为96．7％，而对照组脉通治疗的有效率为80．0％，两者相对比，有显著性差异（P＜0．05），结论“偏瘫宁”对缺血性脑血管病有较好的临床疗效，毒副作用小，可推荐临床应用。     

Persistent neutrophil dysfunction in an adult. Combined defect in chemotaxis, phagocytosis and intracellular killing

Impaired phagocytosis and killing of bacteria by neutrophils were demonstrated repeatedly in a 65 year old man. He had staphylococcal pyarthrosis and osteomyelitis. Phagocytosis and intracellular killing of Staphylococcus aureus by neutrophils of the patient were impaired, but no significant defect was noted when Candida was used as the test organism. Production of ¹⁴CO₂ from glucose-1-¹⁴C, glucose-6-phosphate dehydrogenase levels, nitroblue tetrazolium reduction test and myeloperoxidase levels were all normal in his neutrophils. The monocyte bactericidal capacity for Staph. aureus was normal. Despite normal migration demonstrated by the skin window technic and by the presence of numerous neutrophils in the joint aspirate, studies of neutrophil chemotaxis revealed an impaired response to chemotaxin, and an inhibitor of chemotaxis of normal neutrophils was also found in his serum. However, his serum generated chemotaxin normally. This neutrophil dysfunction appears to differ from that found in chronic granulomatous disease of childhood and other known defects of neutrophil function.     

痉瘫丹治疗创伤性痉挛型截瘫临床疗效分析

目的观察痉瘫丹治疗创伤性痉挛型截瘫的临床疗效,并探讨其作用机制。方法将56例痉挛型截瘫患者分为治疗组(28例)和对照组(28例),对照组采用西药常规治疗,治疗组在常规治疗基础上加用中药痉瘫丹,于治疗前后观察临床疗效。结果两组总有效率,治疗组为89.3%,对照组为53.5%,差异有显著性(P<0.05)。治疗组痉挛消失率为57.2%,明显高于对照组的21.4%,差异有显著性(P<0.01)。结论中药痉瘫丹对痉挛型截瘫临床症状有明显改善作用,与常规治疗合用疗效更显著。