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51.
More than 5500 people were killed in the Hanshin-Awaji earthquake disaster. Most of the neonatal intensive care units (NICU) could not offer proper services as a result of the earthquake and the Hyogo Emergency System for Neonates could not function. No one imagined that such a great disaster would occur in their home town, Kobe; however, the devastation of the quake has raised the opportunity to examine the operation of neonatal medicine in an emergency. We sent out questionnaires to perinatologists in the damaged area 2–3 months after the quake. Some hospitals in the demolished area suffered such serious damage that they could not continue work as NICU, and some in the surrounding area had problems in a number of areas, including staff, room capacity and transport methods. Under these difficult circumstances the greatest problem encountered by staff was maintaining fundamental care in NICU, that is to say keeping temperature, formula (nutrition) and prevention of infection techniques operating. In this report we discuss the effects on neonatal medicine of the earthquake in Kobe. Medical staff struggled patiently and made great efforts to recover and maintain the functioning of NICU. We believe this information will be useful for neonatology staff in other areas which may experience an earthquake in the future. 相似文献
52.
新生儿重症监护病房中高危新生儿听力筛查研究 总被引:16,自引:0,他引:16
目的探讨新生儿重症监护病房(NICU)中高危新生儿采用听力筛查模式和听力障碍发病情况与危险因素。方法采用畸变产物耳声发射(DPOAE)对NICU中高危新生儿病情稳定时进行初筛,未通过者4~6周后作第二次复查,仍未通过者分别于4~6月龄和1岁时进行听觉脑干诱发电位(ABR)检查,两次ABR均未通过者确诊为真性听力损失。结果随机筛查63例高危儿,初检结果阳性22例,阳性率为34.9%,其中有关脑损伤危险因素的阳性率高达71.4%。复检22例,复检率100%,复检阳性5例,通过率为77.3%。4~6月龄和1岁时作ABR检查,确诊有听力障碍2例,其中1例为葡萄糖6磷酸脱氢酶(G6PD)缺乏发生核黄胆,另1例为迟发性维生素K缺乏症引起颅内出血。63例高危新生儿中听力障碍发病率为3.2%。其听力障碍原因均与脑损伤有关。结论NICU中高危新生儿是听力障碍的高发人群,应该常规进行听力筛查,中枢神经系统受损是导致听力障碍的高危因素,DPOAE结合ABR是一种较好的高危新生儿听力筛查方法。 相似文献
53.
Altering the NICU and measuring infants' responses 总被引:8,自引:0,他引:8
Slevin M Farrington N Duffy G Daly L Murphy JF 《Acta paediatrica (Oslo, Norway : 1992)》2000,89(5):577-581
The aim of the study was to measure the impact of a designated Quiet period on the NICU environment and its influence on the infants' physiological and movement responses. The study group comprised 10 preterm infants on assisted ventilation (mean gestational age 28.7 wk (range 24-32 wk), mean birthweight 1,322 g (range 600-2,060 g), mean age 5.2 d). The environment in which the infants were nursed was altered in terms of reduced light, noise, staff activity and infant handling. The infants' heart rate, blood pressure, oxygen saturation and movement responses were recorded during this Quiet period and compared with a period of Normal activity. When the Quiet period was compared with the Normal period (median values), the NICU environment had significantly altered in terms of Light: Quiet period 3.0 Lux, Normal period 254.5 Lux (p < 0.01); Noise: Quiet period 54.0 dB, Normal period 58.0 dB (p < 0.01); Alarm events: Quiet period 491.5 sec, Normal period 1,180.5 sec (p < 0.01); Staff conversation: Quiet period 16.0 occasions per hour, Normal period 60.0 occasions per hour (p < 0.01); Staff activity: Quiet period 25.5 occasions per hour, Normal period 59.0 occasions per hour (p <0.01); Infant handling: Quiet period 0.0 events per hour, Normal period 4.5 events per hour (p < 0.01). Infants' diastolic blood pressure and mean arterial pressure: median reduction of 2 mmHg for both during the Quiet period (p < 0.05). Infants' movements: Quiet period 14.5 movements per hour, Normal period 84.0 movements per hour (p < 0.05). DISCUSSION: This study demonstrates that Quiet periods are feasible for infants undergoing neonatal intensive care. The NICU environment was altered significantly for light, noise, infant handling and staff activity for a specified time period. These changes were associated with a reduced median diastolic blood pressure and mean arterial pressure and a decrease in infant movements. 相似文献
54.
Fluconazole prophylaxis prevents invasive fungal infection in high-risk, very low birth weight infants 总被引:6,自引:0,他引:6
Bertini G Perugi S Dani C Filippi L Pratesi S Rubaltelli FF 《The Journal of pediatrics》2005,147(2):162-165
OBJECTIVES: To evaluate the benefit of fluconazole prophylaxis in preventing invasive fungal infection in very low birth weight (VLBW) infants with central vascular access. STUDY DESIGN: A 3-year baseline period (1998 to 2000) was compared with a subsequent 3-year period (2001 to 2003) during which a different protocol for preventing invasive fungal infection was used. All infants with a birth weight < 1500 g and with central vascular access were eligible for the study. Fluconazole (Diflucan R) was administered for 28 days at a dose of 6 mg/kg every third day during the first week and daily after the first week. RESULTS: There were no significant differences between the baseline and the fluconazole groups in demographic characteristics or risk factors for fungal infection. Fungal infection developed in 9 of the infants in the baseline group and in none of those in the fluconazole group (P=.003). A trend of decreasing mortality rate between the 2 groups (12.6% vs 8.1%; P=.32) was observed but was not statistically significant. No adverse effects of fluconazole therapy were documented. CONCLUSIONS: Fluconazole prophylaxis appeared to be beneficial in preventing invasive fungal infection in VLBW infants. 相似文献
55.
Smith VC Zupancic JA McCormick MC Croen LA Greene J Escobar GJ Richardson DK 《The Journal of pediatrics》2005,146(4):469-473
OBJECTIVE: To examine temporal trends in the rates of severe bronchopulmonary dysplasia (BPD) between 1994 and 2002. STUDY DESIGN: In a retrospective cohort study, all infants with a gestational age (GA) <33 weeks in a large managed care organization were identified. Annual rates of BPD (defined as an oxygen requirement at 36 weeks corrected GA), severe BPD (defined as respiratory support at 36 weeks corrected GA), and death before 36 weeks corrected GA were examined. RESULTS: Of the 5115 infants in the study cohort, 603 (12%) had BPD, including 246 (4.9%) who had severe BPD. There were 481 (9.5%) deaths before 36 weeks corrected GA. Although the decline in BPD in this period was not significant, the rates of severe BPD declined from 9.7% in 1994 to 3.7% in 2002. Controlling for gestational age, the odds ratio (95% CI) for annual rate of decline in severe BPD was 0.890 (0.841-0.941). Controlling for gestational age, deaths before 36 weeks corrected GA also declined, with the odds ratio (CI) for the annual decline being 0.944 (0.896-0.996). CONCLUSIONS: In this study population, the odds of having of BPD remained constant after controlling for GA. However, the odds of having severe BPD declined on average 11% per year between 1994 and 2002. 相似文献
56.
Expectation of pregnancy outcome among mature women 总被引:3,自引:0,他引:3
Porreco RP Harden L Gambotto M Shapiro H 《American journal of obstetrics and gynecology》2005,192(1):38-41
OBJECTIVE: Increasing numbers of mature women are achieving pregnancy largely through assisted reproductive technology (ART). Our objective was to investigate women over 45 years of age to determine the impact of pregnancy complications on newborn outcome. STUDY DESIGN: A study of women older than 45 years at their estimated date of confinement (EDC) was compared with a control group under 36 years at their EDC, matched by parity and plurality. All study patients and controls received uniform obstetric management through a single maternal fetal practice. The primary outcome was gestational age at birth stratified by plurality; secondary outcomes included birth weight, NICU days, composite neonatal morbidity, and a variety of obstetric complications. Wilcoxon signed rank and McNemar's tests were used as appropriate; logistic regression was used to calculate odds ratios (ORs) and CIs. Statistical significance was assumed for P < .05. RESULTS: Fifty study and control patients were identified over a 5-year period. Study patients were older than controls, but the difference in "gamete" age was not significant. There was significantly more assisted reproduction (donor egg) and preeclampsia among study patients. Importantly, gestational age at birth and birth weights stratified by plurality were not different (86% power to detect 2-week gestational age difference, alpha 0.05). Hospital days, NICU days, and composite neonatal morbidity were not different between study patients and controls. CONCLUSION: When controlled for parity and plurality, mature women over 45 years conceiving largely through ART with donor eggs can expect newborn outcomes similar to younger women cared for in the same setting of a high-risk maternal-fetal practice. 相似文献
57.
Hered RW 《The Journal of pediatrics》2004,145(3):308-311
OBJECTIVE: Use of nonsterile eyelid speculae and scleral depressors during screening examinations for retinopathy of prematurity (ROP) in the neonatal intensive care unit (NICU) violates existing infection control recommendations. The objective of this study was to characterize current instrument management and to estimate the prevalence of use of nonsterile instruments. STUDY DESIGN: NICU nurse managers were surveyed. Questionnaires were mailed to 735 NICUs from The United States Neonatologists and Perinatologists Directory. RESULTS: Of 300 surveys returned, 290 reported ROP examinations in their NICUs. Two hundred ten (72%) of 290 NICUs reported supplying instruments. Seventy-five (36%) of 210 NICUs supplying instruments reported a best practice on the basis of current guidelines. Twenty-six (9%) of 290 NICUs reported eye infections as a result of ROP examinations. Reported infection was more frequent (19%) among NICUs reporting reuse of instruments ( P =.019) and more frequent (17%) among NICUs in which ophthalmologists brought their own instruments ( P =.021). Only one (2%) NICU reporting best practice also reported eye infections ( P =.004). CONCLUSIONS: ROP instrument management is inconsistent within and between NICUs. Without the exclusive use of sterile instruments, an increased risk of nosocomial infection might exist. Greater attention to sterile instrument management is recommended. 相似文献
58.
OBJECTIVE: To explore concurrent and predictive validity of the Stanford-Binet: Fourth Edition (SB-IV) by comparing scores on the SB-IV with scores from the Battelle Developmental Inventory (BDI) and later achievement scores in preschoolers at risk due to very low birthweight, and/or intraventricular hemorrhage (IVH) and other medical complications. METHODS: At ages 3,4, and 5, 92 preschoolers were tested with the SB-IV and BDI as part of an 8-year early intervention follow-up. RESULTS: The SB-IV and BDI concurrent correlations at ages 3, 4, and 5 were statistically significant (r = .73-.78, p < .0001), as were predictive correlations (r = .58-.85, p < .0001). However, the BDI and SB-IV failed to place the children in the same categories for intervention services. With the BDI as the comparison measure, SB-IV failed to detect 87% of the children who were "delayed" (by BDI) at age 3 and 50% of the "delayed" children at age 5. CONCLUSIONS: Caution is recommended when using the SB-IV to assess high risk for early intervention eligibility. 相似文献
59.
目的分析NICU内患儿腋静脉留置套管针穿刺失败的原因,制定相应的对策,提高腋静脉穿刺成功率。方法对临床上60例腋静脉穿刺失败的原因进行研究分析。结果操作者的心理素质、技术操作水平及患儿个体差异是影响穿刺失败的原因。结论为提高穿刺成功率,需要加强护士的心理素质、腋静脉穿刺技术的培训,只有很好地掌握了穿刺要领,才能穿刺成功。 相似文献
60.
Claire Zores André Dufour Claire Langlet Benoît Escande Dominique Astruc Pierre Kuhn 《Early human development》2013