漫谈朱雀汤

探讨朱雀汤的来源、方义,并从古代和现代研究总结朱雀汤的临床应用和名家经验。临床应用的阴虚内热、心肾不变为宗旨。     

广西莪术不同炮制对姜黄素成分及镇痛抗炎的影响

目的：探讨不同炮制方法对广西莪术姜黄素含量及镇痛抗炎作用的影响。 方法：用HPLC测定广西莪术生品、醋煮品、醋炙品姜黄素的含量;采用小鼠耳廓肿胀法、腹腔染料渗出法研究其抗炎作用;采用热板法、扭体法观察其镇痛作用。结果：广西莪术各炮制品姜黄素的含量为：生品＞醋炙品＞醋煮品;醋制炮制后具有较强的镇痛抗炎作用。结论：不同炮制方法对广西莪术质量有一定的影响。     

《小儿药证直诀》用药特点浅析

建立<小儿药证直诀>所载方药数据库,利用统计学方法分析钱乙治疗小儿疾病的用药特点为:组方药少力专、善用毒药、剂型灵活、重视肝脾胃肺.     

中医“脾”“胰”辩

中医“脾”和西医“pancreas”的对应更符合《内经》的本义,而“脾”和“spleen”的混同很可能是中西医交流之初翻译误读的结果。英语“spleen”汉语习惯翻译成“脾”,许多人想当然的认为中医的“脾”和西医的“spleen”也是同一个东西。然而,仔细回顾中医基础理论关于“脾”的有关论述以及中西医交流的历史,可以发现：中医“脾”和西医“pancreas”的对应其实更符合中医“脾”的本义,而“脾”和“spleen”的混同很可能是中西医交流之初翻译误读的结果。兹论述于下。     

Improvement in delusions and hallucinations in patients with dementia with Lewy bodies upon administration of yokukansan,a traditional Japanese medicine

Background: This multicentre open‐label trial examined the efficacy and safety of the traditional Japanese medicine, or Kampo medicine, yokukansan (YKS), for behavioural and psychological symptoms of dementia (BPSD) in patients with dementia with Lewy bodies. Methods: Sixty‐three dementia with Lewy bodies patients with probable BPSD (M : W, 30 : 33; mean age, 78.2 ± 5.8 years) were enrolled and treated with YKS for 4 weeks. Results: Significant improvements in Neuropsychiatric Inventory scores (mean decrease, 12.5 points; P < 0.001) and Zarit Burden Interview‐Japanese edition tests (mean decrease, 3.6 points; P= 0.024) were observed. In patients who consented to an assessment after 2 weeks of treatment, a time‐dependent significant improvement was observed in the Neuropsychiatric Inventory score (n= 23; mean decrease, 14.4; P < 0.001), each subscale, including delusions and hallucinations, the Zarit Burden Interview‐Japanese edition (n= 22; mean decrease, 8.2; P < 0.01) and the behavioural pathology in Alzheimer's disease insomnia subscale. The Mini‐Mental State Examination and the Disability Assessment for Dementia (DAD) showed no significant change. Adverse events were observed in 11 (18%) patients. Three patients (5%) discontinued YKS due to adverse reactions, namely, spasticity and exacerbation of BPSD, edema, and nausea. Hypokalaemia (<3.5 mEq/L) was present in four patients (6%) at the study endpoint. Worsening of extrapyramidal symptoms was not observed. Conclusion: YKS improved BPSD in dementia with Lewy bodies patients and caregiver burden scores without deterioration in cognitive function. YKS is useful for the treatment of delusions and hallucinations in BPSD.     

凉血解毒饮2号治疗慢性荨麻疹56例临床观察

目的 探讨凉血解毒饮2号治疗慢性荨麻疹的临床疗效与治疗机制.方法 本研究共112例慢性荨麻疹患者,其中56例作为治疗组采用凉血解毒饮2号治疗,56例作为对照组口服氯雷他定片,两组进行临床对照观察.结果 与对照组相比,治疗组经凉血解毒饮2号治疗后荨麻疹症状有明显减轻,差异有统计学意义(P＜0.05).结论 凉血解毒饮2号治疗慢性荨麻疹有效、安全,适于推广应用.     

四川凉山彝族9项头面部群体遗传学特征

目的了解四川凉山彝族头面部群体遗传学特征。方法用随机整群抽样法,调查313例(男性204例,女性109例)四川凉山彝族中学生9项遗传学指标。结果 (1)彝族有眦褶率、上眼睑有褶皱率、铲型门齿率、凸型鼻梁率、宽型鼻孔率、突型下颏率、有耳垂率、尖形发际率和卷发率分别为58.47%、85.94%、95.85%、2.87%、77.32%、4.15%、72.84%、37.70%和23.00%。(2)额头发际有性别差异。结论四川凉山彝族9项头面部群体遗传学特征与其他族群存在差异。     

Effects of Talaromyces marneffei infection on mortality of HIV/AIDS patients in southern China: a retrospective cohort study

Objective

Talaromyces marneffei is an opportunistic infection with high morbidity among human immunodeficiency virus (HIV)/AIDS patients in Southeast Asia and southern China. Its effects on mortality in HIV/AIDS patients has not been clearly elucidated.

蔡氏三联疗法治疗白癜风的结果观察与护理

目的探讨蔡瑞康教授三联疗法治疗白癜风的结果观察与护理对策。方法采用中西医结合的方法对68例白癜风患者进行门诊治疗,以2个月为1疗程按拟定标准进行阶段疗效评估,3个疗程结束后进行总体疗效评价和不良反应统计。结果 68例共计142处靶皮损中,61.3%的靶皮损在治疗2个月时已见效,随着疗程的增加,有效率逐渐升高,治疗4个月时,总有效率达84.5%,治愈率达24.6%,治疗6个月时,总有效率达95%,治愈率达43.7%;3个疗程结束后,共计3例患者出现不良反应（占4.41%）,均发生在PUVA照射的局部皮肤,1例患者出现红肿水泡伴痒感,2例患者出现皮肤增厚脱屑。结论蔡瑞康教授原创的中西医结合三联疗法治疗白癜风安全有效,但治疗过程应注意加强专科临床观察,个别情况下出现不良反应时应及时采取相应的专科护理措施。     

试论慢性胰腺炎继发糖尿病的中医辨治

目的慢性胰腺炎继发糖尿病的发病率逐年增高,且临床误诊率极高,但目前慢性胰腺炎继发糖尿病尚缺乏系统的证候规律认识。笔者从胰脾解剖、生理、病理分析了胰脾相关理论,认为在功能上"胰属脾"。同时基于胰脾功能相关的理论,对慢性胰腺炎继发糖尿病的病因病机做了探讨,分别从"脾损为本,分期论治""以通为用,护胰缓糖""补气升提,减脆稳糖"等方面对辨治规律做了论述。