胸痹颗粒治疗心肌梗死后心室重构(气虚痰瘀型)的临床观察

目的 观察胸痹颗粒治疗心肌梗死后心室重构(气虚痰瘀型)的临床疗效.方法 将60例患者随机分为2组.西药组30例予开搏通6.25 mg,每日3次口服;中药组30例予胸痹颗粒,每次1袋,每日3次口服.2组均8个月为1个疗程.观察2组治疗前后心室重构指标变化、逆转心室重构疗效变化及中医症状疗效变化.结果 2组在降低心室重构指标值、逆转心室重构疗效及改善中医症状上均无显著性差异(P＞0.05).结论 胸痹颗粒有明显的逆转心肌梗死后心室重构的作用,改善临床症状显著,值得临床推广.     

肺炎1号方的组方思路及理论创新

认为广东地区新型冠状病毒肺炎(简称"新冠肺炎")是以热毒为基本属性的疫疠之气所致,从发病季节及病邪性质看,可归属于温邪为主的疫疠范畴,可称之为"风温""温热疫".基于对广东地区新冠肺炎病因、病机的认识,分析肺炎1号方的组方思路与在清热解毒、透邪清宣及止咳化痰的同时使用益气养阴的理论创新点,为积极开展中医药救治新冠肺炎及...     

从风论治室性早搏

室性早搏属中医"心悸"范畴,其发病特点与中医"风证"有相似之处."风为百病之长",外风、内风均可导致室性早搏的发生.外风可由表及里或直中于心而发病,多伴有表证,治疗上应注重风药的使用;内风多由热极生风、痰热生风、肝风内动、血虚生风、阴虚动风等扰动心神而发病,在清热、化痰、平肝、养血、滋阴的基础上,亦当注重祛风熄风."邪...     

从“一气周流”论述细胞焦亡与代谢综合征血管内皮损伤的相关性

“一气周流”是中医经典理论,其核心思想认为中气(脾胃之气)是整个气机运转的枢纽。脾胃虚弱,肝气郁结,水谷精微运化疏泄失常,日久痰浊瘀血内生,积聚于血管,引起代谢综合征血管内皮损伤。临床及实验研究均证实健脾疏肝方剂柴芪汤对代谢综合征及相关血管内皮损伤具有较好改善作用。细胞焦亡是一种促炎性程序性细胞死亡方式,在血管内皮炎症反应中具有重要作用,这一过程类似于中医“痰瘀浊毒”的积聚。基于“一气周流”理论探讨细胞焦亡与代谢综合征血管内皮损伤的机制,为中医经典理论和中医药防治代谢综合征血管并发症提供理论依据。     

中医正邪理论与抑癌基因和癌基因在肿瘤中的相关性

正邪理论是中医认识疾病的基本模型之一,其中蕴含有对立统一的哲学思想。肿瘤的发生发展与基因突变相关,抑癌基因与癌基因在分子层面上的行为可以作为一种症状纳入正邪理论体系中。分析抑癌基因与癌基因在肿瘤发生、发展中表现出的正邪关系,有利于将现代医学的研究结论与中医基础理论相联系,从而扩充正邪理论的内涵,以期为肿瘤的中医治疗提供更多证据支撑。     

养心氏片从“玄府-络脉”理论辨治冠状动脉性心脏病的应用

玄府和络脉同为机体的微细结构,在气血津液运转方面发挥重要作用。玄府作为门户,有开阖之特性;络脉曲折蜿蜒,具通路之功能。玄府的开阖有序支撑人体气血宣通,津液布输,精神流转;络脉通畅维持气血津液,阴阳营卫的有序运行,二者共同运作源源不断为周身提供滋养。冠状动脉性心脏病属于中医学“胸痹”范畴,主要为玄府闭塞、络脉瘀阻所致。现分析养心氏片组方用药特色,结合现代药理研究,探讨其通过益气开玄、活络通脉治疗冠状动脉性心脏病的应用。     

Treatment of myasthenia gravis with the method of tonifying spleen and replenishing qi in traditional Chinese medicine: A protocol for systematic review and meta-analysis

Background:Myasthenia gravis (MG) is an autoimmune disease that is associated with the production of autoantibodies. The symptoms of MG are mainly mediated by pathogenic antibodies directed against nicotinic acetylcholine receptors, resulting in a decrease in the number of acetylcholine receptors molecules on the postsynaptic membrane of the neuromuscular junction endplate, leading to clinical symptoms of muscle fatigue and weakness. At present, traditional Chinese medicine (TCM) treatment of MG has a better effect by tonifying spleen and replenishing qi. The purpose of this study was to systematically evaluate the efficacy and safety of TCM therapy for tonifying spleen and replenishing qi in the treatment of myasthenia gravis.Methods:We searched the following databases from their establishment until December 2021: PubMed, Cochrane Library, EMBASE, Web of Science, Springer, CNKI, Wanfang, China Biomedical Database, China Science and Technology Journal Database, Chinese Knowledge Infrastructure, China Clinical Trial Registry, and Baidu Scholars. The literature search language was limited to Chinese and English, and publication time and status were not limited. Randomized controlled trials (RCTs) were included. Two researchers independently searched and screened the articles, assessed their quality, and used the RevMan 5.4.1 software to perform a meta-analysis of the included literature.Results:This study compared the main outcome indicators: efficacy rate, recurrence rate, quality of life, and quantitative myasthenia gravis (QMG). Secondary outcome indicators were the clinical absolute score, TCM syndrome score, serum acetylcholine receptor antibody level, and electromyogram low-frequency repetitive nerve stimulation.Conclusion:This study aimed to evaluate whether the TCM method of tonifying spleen and replenishing qi is effective in the treatment of MG and to provide evidence-based data.Ethics and dissemination:The protocol of the systematic review did not require ethical approval because it did not involve human subjects. This article will be published in peer-reviewed journals and will be presented at conferences.     

从天到人--《黄帝内经》认识人体的起始角度

《黄帝内经》以“天人合一”作为其医学理论的基础,蕴涵着丰富的中国传统自然哲学思想。认为,“人以天地之气生,四时之法成”。人源于天地,并分享了一些天地的特性,天与人存在某些方面的相似性。并且,人与天也存在一定程度上的相通。以何相通?气也。天人相应,以天作为人的根据,这正是《黄帝内经》认识人体的起始角度。     

中药雾化吸入联合常规疗法与护理措施干预甲状腺癌术后声音嘶哑效果分析

目的:观察在常规治疗与护理基础上加用中药雾化吸入治疗甲状腺癌术后声音嘶哑的效果。方法:纳入120例气阴两虚型甲状腺癌术后声音嘶哑患者,应用随机数字表法分为2组各60例,2组均采用常规治疗与护理措施干预,观察组加用中药雾化吸入治疗,2组疗程均为1个月。治疗前后评价2组患者的声音嘶哑情况评分,评价患者在观察期的用药依从性,出院前评价护理满意度,并比较2组的治疗效果。结果:治疗1个月后,观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。观察组患者的用药依从性情况较好,绝大多数患者能够按时按量用药,不受症状波动的影响,2组比较,差异有统计学意义(P<0.05)。观察组护理满意度高于对照组,差异有统计学意义(P<0.05)。结论:在常规治疗与护理基础上加用中药雾化吸入干预甲状腺癌术后声音嘶哑,可有效改善声音嘶哑、提高疗效,提高患者的用药依从性和对护理措施的满意度。     

浅谈肝俞龙虎交战针法为主治疗排卵障碍性不孕

结合中医理论及外界影响因素分析认为,排卵障碍性不孕以"肝气郁结、疏泄失调"为病机,治则立"疏肝解郁、调畅气机"为大法,探讨治疗该病选用肝俞施用龙虎交战针法的理论依据。为针灸治疗排卵障碍性不孕提供新的思路及方法,同时也体现了古典针法创新性的运用。