中医药分期联合西药治疗真菌性角膜溃疡随机平行对照研究

[目的]观察中医药分期联合西药治疗真菌性角膜溃疡疗效。[方法]使用随机平行对照方法,将55例住院患者按病志号抽签简单随机分为两组。对照组27例氟康唑滴眼液与那他霉素滴眼液交替点眼,1次/h;托吡卡胺滴眼液,3次/d;妥布霉素滴眼液冲洗结膜囊,6次/d;维生素C,50mg/次,3次/d。治疗组28例早期龙胆泻肝汤(龙胆草12g,栀子9g,黄芩6g,柴胡12g,车前子10g,生地黄12g,泽泻、夏枯草、茯苓、厚朴各9g,甘草6g);中晚期托里消毒散(黄芪20g,当归、白芍、川芎、党参、白术、茯苓各10g,甘草6g,金银花15g,连翘、蝉蜕、白蒺藜各10g);水煎200mL,1剂/d,早晚口服;西药治疗同对照组。连续治疗20d为1疗程。观测临床症状、角膜、前房、视力、真菌菌丝、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈11例,有效14例,无效3例,总有效率89.29%。对照组痊愈4例,有效14例,无效9例,总有效率66.67%。治疗组疗效优于对照组(P0.05)。[结论]中医药分期联合西药治疗真菌性角膜溃疡效果显著,值得推广。     

何炳元教授用清透法治疗皮肤病经验

何炳元教授用清法辨治热毒蕴结性皮肤病,注意透邪外出、寓透于清,取其开闭、泄毒、转气、透热之功,既清泄火毒,又开门逐邪,事半功倍。     

何炳元教授运用部位辨证诊治外科疾病的经验

何炳元教授运用发病部位与致病因素之间的关系,诊治某些外科疾病,常收到良好的效果：发于人体上部的疾病,多属风温、风热,治宜散风清热;发于人体中部的疾病,多属气郁、火郁,治宜疏肝清热;发于人体下部的疾病,多属湿火、湿热,治宜利湿清热。     

Ventilation-based segmentation of the lungs using hyperpolarized (3)He MRI

Purpose:

To develop an automated segmentation method to differentiate the ventilated lung volume on ³He magnetic resonance imaging (MRI).

Materials and Methods:

Computational processing (CP) for each subject consisted of the following three essential steps: 1) inhomogeneity bias correction, 2) whole lung segmentation, and 3) subdivision of the lung segmentation into regions of similar ventilation. Evaluation consisted of two comparative analyses: i) comparison of the number of defects scored by two human readers in 43 subjects, and ii) simultaneous truth and performance level estimation (STAPLE) in 18 subjects in which the ventilation defects were manually segmented by four human readers.

Results:

There was excellent correlation between the number of ventilation defects tabulated by CP and reader #1 (intraclass correlation coefficient [ICC] = 0.86), CP and reader #2 (ICC = 0.85), and between the two readers (ICC = 0.97). The STAPLE results from the second analysis yielded the following sensitivity/specificity numbers: CP (0.898/0.905), radiologist #1 (0.743/0.897), radiologist #2 (0.501/0.985), radiologist #3 (0.898/0.848), and the first author (0.600/0.984).

Conclusion:

We developed and evaluated an automated method for quantifying the ventilated lung volume on ³He MRI. The findings strongly indicate that our proposed algorithmic processing may be a reliable, automatic method for quantitating ventilation defects. J. Magn. Reson. Imaging 2011;. © 2011 Wiley‐Liss, Inc.     

一部难得的好医书——《国医大师何任医案墨迹》

"读书不如读案。"医案向来是中医学习与提高的重要途径。《国医大师何任医案墨迹》,精选何老数则附有精辟按语的经典医案,可师可法。更以何老亲书的墨迹体现,隐含中医学术的深邃意蕴与国医大师的厚实功底,确是一部既可示范中医处方特色,也可供书法爱好者欣赏、临摹、收藏的难得的好医书。     

何廉臣《感症宝筏》手校稿本述考

《感症宝筏》原名《伤寒指掌》,为清代医家吴贞所著,何廉臣重订,体现了清代中后期寒温思想的融合。该稿本为何廉臣出版该书时手校之底本,由其子抄录,内有多处校对、抄录笔迹及校改痕迹。从该稿本的抄写和体例、稿本与通行本之对比、该稿本中的修改符号等几个方面进行论述,探讨其学术与文物价值。     

何乃举主任中医师伤寒六经辨治癌症学术经验

癌症是世界的难题,是全球人类的灾难。西医放疗、化疗、手术被誉为抗肿瘤的“三板斧”,是治疗癌症的传统方法。何乃举主任中医师遍访全国中医界名家及民间老中医,加之长期的临床实践,形成从伤寒六经辨治癌症的思路经验,从六经辨证仲景已经把癌症早有定位,按照六经辨证学术研究,脏腑本能之气衰败,三阳经外感入里化内热,内热不除,耗伤三阴,引起三阳内闭,闭则不通,聚焦在脏腑,泛滥成灾,这是肾亏骨空内伤。内伤三阳热耗,形成阴不足,阳有余,阴阳失调,必然使脏腑大病。按六经辨治方法,泄内实热,顺水行舟,给病邪找出路,热去阴自复。开鬼门解表,洁净腑利小便。把握伤寒六经辨治规律,诊治癌症也有十之六七,也能见病之源,病跟经走,方跟病行,经病同行,六经大道找病,切中病源。     

何立群教授运用中医药治疗慢性肾脏病经验集锦

慢性肾脏病目前是全球性的公共健康问题,但慢性肾脏病发病初期临床表现及体征较少,很容易被忽视,若未在早中期给予及时治疗,将很快进展至终末期肾病(ESRD)。现作者就何立群教授运用中医药治疗慢性肾脏病的临床思路及经验进行整理总结,并附验案1则,与诸同道共享。