除皱术美容就医者的精神焦虑分析与护理

目的通过对除皱术就医者的精神焦虑分析,探讨相应的护理对策。方法采用汉密顿焦虑量表,系统评价焦虑程度。结果按照汉密顿焦虑量表的分析,为除皱术就医者的针对性护理提供了指导。结论根据汉密顿焦虑量表进行分析,提高了护理效率及除皱术就医者的满意度。     

Shared impairment in associative learning in schizophrenia and bipolar disorder

Background

Schizophrenia (SCZ) and bipolar disorder (BD) share some cognitive commonalities. However, the role of associative learning, which is a cornerstone of human cognition mainly relying on hippocampus, has been under-investigated. We assessed behavioral performance during associative learning in a group of SCZ, BD and healthy controls (HC).

Methods

Nineteen patients with SCZ (36 ± 8.1 years; 13 males, 6 females; all Caucasians), 14 patients with BD (41 ± 9.6 years; 5 males, 9 females; all Caucasians) and 45 HC (27.7 ± 6.9 years; 18 males, 27 females; all Caucasians) were studied. Learning was assessed using an established object-location paired-associative learning paradigm. Subjects learned associations between nine equi-familiar common objects and locations in a nine-location grid. Performance data were analyzed in a repeated measures analysis of variance with time (repeated) and group as factors.

Results

Learning curves (performance = 1−e^−k?time) fitted to average performance data in the three groups revealed lower learning rates in SCZ and BD (k = 0.17 and k = 0.34) than HC (k = 0.78). Significant effects of group (F = 11.05, p < 0.001) and time (F = 122.06, p < 0.001) on learning performance were observed.

Conclusions

Our study showed that associative learning is impaired in both SCZ and BD, being potentially not affected by medication. Future studies should investigate the neural substrates of learning deficits in SCZ and BD, particularly focusing on hippocampus function and glutamatergic transmission.     

高压氧治疗对老老年男性抑郁症患者HAMD评分的影响及临床疗效

目的探讨高压氧治疗对老老年男性抑郁症患者汉密尔顿抑郁量表(HAMD)评分影响及临床疗效观察。方法将168例老老年男性抑郁症患者随机分为对照组(度洛西汀+常规护理)和试验组(度洛西汀+常规护理+高压氧)。8周后对两组治疗前后的临床疗效进行比较,并进行汉密尔顿抑郁分级量表(HAMD)评分比较。结果试验组治疗后的临床疗效及HAMD评分均有明显改善,有极显著性差异(P<0.01)。治疗后对照组与试验组比较差异有统计学意义(P<0.05)。结论高压氧联合常规治疗对老老年男性抑郁症患者有显著临床疗效,且HAMD评分显著下降。     

艾司西酞普兰与阿米替林治疗抑郁症对照研究

目的：比较艾司西酞普兰与阿米替林治疗抑郁症的疗效及安全性。方法：将50例患者随机分为两组,研究组（A组）25例,口服艾司西酞普兰治疗;对照组（B组）25例,口服阿米替林治疗。观察6周,与治疗前及治疗后第1、2、4、6周末采用汉密尔顿抑郁量表和临床疗效总评定量表评定临床疗效,不良反应量表评定不良反应。结果：治疗第6周末研究组显效率为96%,对照组显效率为92%,两组差异无统计学意义（P〉0.05）,副反应研究组显著少于对照组（P〈0.01）。结论：对于抑郁症,艾司西酞普兰与阿米替林疗效相当,但艾司西酞普兰安全性好,依从性好。     

Chronic fatigue syndrome treated by the traditional Chinese procedure abdominal tuina: a randomized controlled clinical trial

Objective

To evaluate the effect of the traditional Chinese procedure abdominal Tuina (AT) on chronic fatigue syndrome (CFS).

五行音乐佐治老年抑郁症临床研究

目的 观察中医五行音乐对老年抑郁症患者抑郁状态的影响。方法 采用前瞻、随机、对照的方法,将91例老年抑郁症患者分为治疗组（五行音乐组,n=47）、阳性对照组（西方音乐组,n=23）和阴性对照组（不接受音乐治疗,n=21）,各组患者在接受常规抗抑郁治疗的基础上分别聆听不同的音乐,治疗前和治疗4周后分别采用抑郁自评量表（self-rating depression scale, SDS）、汉密尔顿抑郁量表（Hamilton depression rating scale,HAMD）测评患者的抑郁状态,观察临床疗效及不良反应。结果 治疗组治疗后SDS评分,HAMD总分及各因子分均较治疗前显著降低（P<0.05）;治疗组治疗后SDS降低值,HAMD总分及焦虑/躯体化因子评分和睡眠障碍因子评分降低值显著大于阳性对照组和阴性对照组（P<0.05）。治疗组临床疗效明显优于阴性对照组（P<0.05）。结论 中医五行音乐可以改善老年抑郁症患者的抑郁症状。     

Benefit of gluten‐free diet in idiopathic pulmonary hemosiderosis in association with celiac disease

Lane–Hamilton syndrome refers to the uncommon co‐occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co‐existing non‐diarrheal CD. Institution of gluten‐free diet in each of the three children resulted in amelioration of the pulmonary symptoms along with improvement of anthropometric parameters and hemoglobin over a short‐term follow‐up period of 8–17 months. Inhaled/oral steroids and immunosuppressants could be weaned off after dietary exclusion therapy in each of the three children. Gluten free diet should be instituted in all patients diagnosed with Lane–Hamilton syndrome. It ameliorates both the pulmonary as well as the intestinal symptoms although the precise mechanism of the pulmonary response is as yet unclear. Pediatr Pulmonol. 2011; 46:302–305. © 2011 Wiley‐Liss, Inc.     

电针对盐酸帕罗西汀治疗轻中度抑郁症患者增效减毒作用的临床研究

目的 观察电针对盐酸帕罗西汀治疗轻、中度抑郁症患者的临床疗效及药物不良反应的影响.方法 将55例轻、中度抑郁症患者随机分为A组(盐酸帕罗西汀对照组)29例,B组(电针+盐酸帕罗西汀组)26例,疗程6周.观察治疗前及治疗1,2,4,6周后汉密尔顿抑郁量表(HAMD)、抗抑郁药副反应量表(SERS)总评分变化情况.结果 HAMD评分显示,A组治疗2周后,B组治疗1周后,同组与治疗前比较,差异有显著性意义(P<0.05),治疗2周后2组间HAMD评分比较有显著性意义.A组总有效率71.4%,B组88.0%,差异有显著性意义(P<0.05).SERS评分B组在治疗4周后与治疗前比较差异有显著性意义(P<0.05),治疗6周后有极显著性意义(P<0.01).结论 电针能够增强盐酸帕罗西汀治疗抑郁症疗效且显著降低药物引起的不良反应.     

Myometrial electrophysiologic activity and gap junctions in the pregnant rabbit

Electromyographic activity of the myometrium, intrauterine pressure, and myometrial gap junctions were examined in rabbits at various stages of pregnancy and during parturition. Electromyographic activity occurred throughout pregnancy and was characterized by electromyographic bursts lasting up to 5 minutes at a frequency of one to four per hour. The gap junction area of plasma membrane showed a significant increase at delivery at a time when electromyographic activity changed to rhythmic bursts of short duration at a frequency of about one per minute. This study shows that the rabbit uterus is active throughout pregnancy; furthermore, the development of large numbers of gap junctions between myometrial cells occurs at a time when uterine activity changes to the expulsive activity required for labor.     

Outcome in infants 501 to 1000 gm birth weight delivered to residents of the McMaster Health Region

The mortality and morbidity for all 255 live births of infants with birth weight 501 to 1000 gm and delivered to residents of a geographically defined region between 1977 and 1980 are reported. In all, 117 (46%) infants were discharged alive; there were four postdischarge deaths, and three infants were lost to follow-up. The mean birth weight and gestational age of the survivors was 850 +/- 118 gm and 27.1 +/- 2 weeks, respectively. Neurosensory handicaps were detected in 26 (24%) of 110 survivors followed for a minimum of 2 years corrected age. In addition, 29 (26%) infants had nonneurologic problems and 55 (50%) were considered apparently normal. Within 100 gm birth weight groups, survival improved significantly with increasing birth weight, but the handicap rate among survivors remained relatively constant. These figures are proposed for use in describing the current prognosis at birth for liveborn tiny infants from comparable unselected populations.