Idiopathic spinal extradural lipomas: three cases and review of the literature

Three cases of extradural spinal lipomas in adults are described in which there was no association with steroids. In all three cases the tumors were situated in the lumbar region and the patients were muscular, nonobese males. Two of the three cases had long histories contrary to those previously reported. Preceding transient neurological symptoms were noted in two of the three cases. The etiology of this phenomenon is discussed. It is possible that these lipomas, which are not associated with steroids, may represent a different spectrum of disease.     

Extradural block in obstetric patients: review of experience with gravity administration

Charts of 2284 obstetric patients who received extradural block with gravity administration of local anaesthetic were evaluated retrospectively. Despite a 1.3% incidence of vascular puncture and a 1.8% incidence of dural puncture, accidental intravascular or intrathecal injection of local anaesthetic did not occur. We propose that this method may be safer than the traditional "injection by needle" technique, and has a high degree of "visualization" of the otherwise "blind" extradural block procedure.     

外伤性后颅窝硬膜外血肿的诊治探讨

目的探讨外伤性后颅窝硬膜外血肿的诊断与治疗。方法回顾性分析34例外伤性后颅窝硬膜外山肿的临床资料。结果手术治疗30例,保守治疗4例。根据GOS评分结果:良好25例,中残4例.重残2例,死亡3例。结论CT扫描是诊断外伤性后颅窝硬膜外向肿的首选检查方法。外伤性后颅窝硬膜血肿及早确诊后,尽早手术,预后良好。     

新生化冲剂的主要药效学研究

目的研究新生化冲剂的主要药效作用.方法采用灌胃给药,以生理盐水作为阴性对照组,生化汤丸作为阳性对照组,观察新生化冲剂高剂量、中剂量、低剂量对雌激素引起的小鼠子宫增重的作用、对醋酸引起扭体反应的作用及对小鼠单核吞噬细胞吞噬功能的影响.结果新生化冲剂高,中剂量与生理盐水组比较具有显著抑制己烯雌酚促进性成熟小鼠子宫增重作用(P＜0.01)、提高小鼠单核吞噬细胞吞噬功能(P＜0.01),新生化冲剂高剂量与生理盐水组比较具有抑制醋酸引起扭体反应的次数(P＜0.05).结论新生化冲剂能抑制己烯雌酚增重子宫的作用,并具有镇痛及提高机体免疫功能的作用.     

我院2001年癌症患者麻醉性镇痛药品应用情况调查与分析

目的 :了解我院治疗癌痛的麻醉性镇痛药的应用情况 ,为临床合理用药提供参考。方法 :根据WHO推荐的限定日剂量 ,对2001年我院麻醉性镇痛药以药物利用指数为指标对处方进行分析 ,从而评价该类药物应用的合理性。结果与结论 :调查表明 ,我院癌症麻醉性镇痛药用药较为合理 ,临床基本能够正确理解和把握WHO癌症“三阶梯止痛”方案     

A simple system of intracranial pressure monitoring for use by non-neurosurgeons

A technique is described for intracranial pressure monitoring that can be used in the intensive care unit by doctors with no neurosurgical experience. The system uses the extradural route, thus reducing the risks of intracranial haemorrhage and infection associated with techniques requiring opening of the dura and cannulating the brain.     

Hemangiopericytoma of thoracic spine: a rare bony tumor

Case report We report the case of a 16-year-old girl who developed hemangiopericytoma of the thoracic spine; the main clinical symptoms were of spastic paraparesis with sensory involvement and uro-fecal incontinence. She was initially put on antitubercular treatment keeping in mind the endemicity of tuberculosis in the region. When she deteriorated on conservative management, she was operated upon, and the histopathological report was suggestive of hemangiopericytoma. Materials and methods Additional immunocytochemistry was performed in the paraffin-embedded tumor sections. Conclusions An extremely rare case of primary epidural malignant hemangiopericytoma of the thoracic spinal column is described. It is a rare tumor, which is locally aggressive, and a potentially malignant tumor. The tumor is more commonly found in the cranium, and spinal involvement is rare, and only few case reports could be retrieved from the literature. We discuss the clinical profile, management, and outcome of spinal hemangiopericytomas along with pertinent review of the literature.     

Naproxen suppository: Tissue response and comparative bioavailability

Summary The absorption of naproxen from Witepsol and Carbowax suppository bases was found to compare closely to that from an equivalent oral dose. Although the drug was readily absorbed from both rectal formulations, naproxen in Witepsol base produced a more rapid rise of plasma levels. — No significant local tissue irritation occurred following a course of six suppositories as determined by anoscopy and rectal biopsy. — No objective or subjective side effects were noted.     

硬膜外入路切除巨大海绵窦海绵状血管瘤的临床分析

目的探讨硬膜外入路切除巨大海绵窦海绵状血管瘤的临床效果。方法从2008年5月至2013年5月收治的海绵窦海绵状血管瘤患者中随机选择15例进行研究。对患者实施硬膜外入路切除术,术后进行定期随访,观察记录患者的治疗效果和脑神经功能情况等。结果海绵窦海绵状血管瘤全切除的有11例,近全切除2例,次全切除1例,部分切除1例。末次随访可得:所有患者的临床症状均得到缓解或者显著改善。结论临床采用硬膜外入路切除术治疗巨大海绵窦海绵状血管瘤疗效确切,且可以一定程度保存患者的脑神经功能,值得临床推广应用。