What is the purpose of launching World Journal of Gastrointestinal Pharmacology and Therapeutics?

The first issue of World Journal of Gastrointestinal Pharmacology and Therapeutics (WJGPT), whose preparatory work was initiated on September 27, 2008, will be published on February 6, 2010. The WJGPT Editorial Board has now been established and consists of 188 distinguished experts from 36 countries. Our purpose of launching WJGPT is to publish peer-reviewed, high-quality articles via an open-access online publishing model, thereby acting as a platform for communication between peers and the wider public, and maximizing the benefits to editorial board members, authors and readers.     

华东地区制造型企业职员工作倦怠调查

目的：了解华东地区制造型企业职员工作倦怠状况，方法：用Maslach倦怠量表一通用版（MBI-General Survey）对华东地区制造型企业283名职员进行了调查。结果：①华东地区制造型企业职员存在较高程度的工作倦怠，情绪衰竭和玩世不恭程度较高，个人成就感程度较低。②职员人口统计学变量和企业性质，会不同程度影响职员工作倦怠。工作倦怠体现在性别和年龄上的差异不显著，而在婚姻、受教育程度、工龄和企业性质上差异较为显著。结论：华东地区制造型企业职员存在工作倦怠，值得进一步研究。     

Importance of Change Appraisal for Employee Well-being during Organizational Restructuring: Findings from the Finnish Paper Industry’s Extensive Transition

The global recession has forced the Finnish forest industry to carry out majorrestructuring activities. Employees have faced different kinds of restructuring, mainlyaimed at reducing staff and production. Many studies have shown the negative consequencesof restructuring on employee well-being by using negative, ill-health indicators. Our aimis to examine the extent to which change appraisal influences both the negative andpositive aspects of work-related well-being among employees who continue working in theorganization after the restructuring process. We also examine the role of different actors(top management, immediate supervisor, employees themselves) in how the change isappraised. The study investigated blue-collar employees working in the Finnish forestindustry during a period of extensive transition (2008–2009). All six participatingfactories underwent restructuring between baseline and the follow-up survey (n=369). Afteradjustment for gender, age and baseline well-being, negative change appraisal increasedthe risk of experiencing more stress and less work enjoyment. Negative change appraisalsthus also damaged the positive, motivational aspects of employee well-being. The resultsshowed the importance of offering employees the opportunity to participate in the planningof changes related to their work as regards positive change appraisal.     

2010—2012年无锡市118253名从业人员戊型肝炎IgM抗体检测分析

目的了解无锡市从业人员戊型肝炎病毒感染状况。方法对无锡市2010—2012年118253名从业人员戊型肝炎病毒IgM抗体进行检测。结果118253名从业人员中戊型肝炎病毒IgM抗体阳性者124名,阳性率为0．11％。其中从事食品行业者阳性82名,阳性率为0．12％;公共场所等行业阳性者42名,阳性率为0．09％。结论无锡市从业人员戊型肝炎IgM抗体阳性率低,且3年来无明显变化。     

乌鲁木齐部队食品与公共场所从业人员乙肝病毒监测结果分析

目的了解乌鲁木齐部队食品与公共场所从业人员乙型肝炎病毒（hepatitis B virus,HBV）的携带状况,为预防乙肝提供依据。方法采用酶联免疫吸附法（enzyme linked immunosorbent assay,ELISA）对驻乌鲁木齐部队食品与公共场所从业人员检测血清乙型肝炎表面抗原（HBsAg）,并对检验结果进行统计分析。结果2009年共监测从业人员1206人,检出HBsAg阳性8人,阳性率为0．66％,男性从业人员HBsAg阳性率为0．42％、女性为0．83％,差异无统计学意义（P〉0．05）;不同年龄组间HBsAg阳性率差异无统计学意义（P〉0．05）,但≤20岁组阳性率最高;食品与公共场所从业人员血清中HBsAg阳性率差异无统计学意义（（P〉0．05）;汉族与少数民族之间差异有统计学意义（P〈0．01）。结论乌鲁木齐部队食品与公共场所从业人员HBV感染率较低,且随着年龄的增加呈下降趋势,应加强乙肝知识防治的宣传教育,提高乙肝疫苗接种率,保护从业人员的身体健康。     

昌平区食品卫生、公共场所从业人员大便培养结果动态分析

目的了解2004--2012年北京市昌平区食品卫生、公共场所从业人员大便培养检出情况。方法收集2004--2012年间昌平区食品卫生、公共场所从业人员健康检查资料,进行统计学分析（x2检验）。结果2004—2012年健康体检总计672419人,检测出痢疾总计17人,平均检出率为0．003％;每年检出率分别为0．008％、0．002％、0．002％、0．009％、0．002％、0、0．002％、0、0。9年间痢疾检出率逐年减少,差异有统计学意义（X2=25．33,P〈0．05）。9年内未检出伤寒患者。结论每年1次对从业人员进行大便培养检测项目没有现实意义。1年1次的从业人员预防性健康检查中的大便培养检测项目,应从中华人民共和国从业人员预防性健康检查中删去,这样一来,减少了从业人员的经济支出。     

427664名从业人员血清梅毒抗体检测分析

目的了解我市2006-2009年间从业人员梅毒感染情况。方法采用梅毒抗体酶联免疫法(ELISA)和梅毒快速血浆反应素试验(RPR)对427 664名从业人员进行初筛,阳性者采用梅毒螺旋体血球凝集试验(TPPA)进行确诊。结果梅毒抗体阳性133例,阳性率3.110/万,其中男性45例、女性88例,以洗浴从业人员阳性率为最高。结论我市从业人员梅毒感染有上升趋势,应加强对洗浴、美容美发等服务行业从业人员的监测,采取相应预防和控制措施遏制梅毒向一般人群扩散。     

What is the purpose of launching World Journal of Clinical Oncology?

The first issue of World Journal of Clinical Oncology (WJCO), whose preparatory work was initiated on December 20, 2009, will be published on November 10, 2010. The WJCO Editorial Board has now been established and consists of 315 distinguished experts from 33 countries. Our purpose of launching WJCO is to publish peer-reviewed, high-quality articles via an open-access online publishing model, thereby acting as a platform for communication between peers and the wider public, and maximizing the benefits to editorial board members, authors and readers.     

Associations of polychlorinated biphenyl exposure and endogenous hormones with diabetes in post-menopausal women previously employed at a capacitor manufacturing plant

There is an increasing body of literature showing associations of organochlorine exposure with risk of diabetes and insulin resistance. Some studies suggest that associations differ by gender and that diabetes risk, in turn, may be affected by endogenous steroid hormones. This report examines the relationships of serum PCBs and endogenous hormones with history of diabetes in a cohort of persons previously employed at a capacitor manufacturing plant. A total of 118 women were post-menopausal with complete data, of whom 93 were not using steroid hormones in 1996, at the time of examination, which included a survey of exposure and medical history, height, weight and collection of blood and urine for measurements of lipids, liver function, hematologic markers and endogenous hormones. This analysis examines relationships of serum polychlorinated biphenyls (PCBs), work exposure and endogenous hormones with self-reported history of diabetes after control for potential confounders. All PCB exposure groups were significantly related to history of diabetes, but not to insulin resistance as measured by the homeostatic model assessment of insulin resistance (HOMA-IR) in non-diabetics. Diabetes was also independently and inversely associated with follicle stimulating hormone (FSH), dehydroepiandrosterone sulfate (DHEAS) and triiodothyronine (T3) uptake. HOMA-IR was positively associated with body mass index (BMI) and C-reactive protein (CRP) and inversely associated with sex hormone binding globulin (SHBG) and T3 uptake after control for PCB exposure. Possible biologic mechanisms are discussed. This study confirms previous reports relating PCB exposure to diabetes and suggests possible hormonal pathways deserving further exploration.     

广州白云机场口岸从业人员早期梅毒感染流行病学调查

目的了解广州白云机场口岸从业人员梅毒感染情况和流行特点,为口岸从业人员传染病防控提供科学依据和指导。方法用甲苯胺红不加热血清(TRUST)试验做初筛,阳性血清采用梅毒螺旋体抗体明胶颗粒(TPPA)试验确认。所得数据采用SPSS软件进行统计分析。结果对2007—2008年14345名口岸从业人员进行健康体检,检出梅毒感染者39例,检出率为0.27%。其中男性12例,女性27例,男女比例为4:9。年龄分布以30～39岁为主,占感染总人数的48.72%;职业分布以服务行业最多为25人,占感染总人数的64.10%;感染途径以婚外性接触感染为主,占感染者总数的92.31%。结论在控制和预防梅毒的过程中,更应加强宣传教育,使其提高自我保护意识并正确对待和及时治疗。同时要不断提高监测水平,控制和切断梅毒在口岸的传播。