Atypical autonomic regulation in perpetrators of violent domestic abuse

Perpetrators of domestic violence describe symptoms that are compatible with exaggerated autonomic arousal at the time of the domestic violence. This inappropriate arousal may be reflected in altered heart rate regulation. If heart rate is systematically regulated by vagal mechanisms, then increases in heart rate should correlate with decreases in cardiac vagal activity, as indexed by respiratory sinus arrhythmia (RSA). We hypothesized that perpetrators of domestic violence have an alteration in heart rate regulation. To test this hypothesis we compared the results of a postural shift performed on perpetrators, healthy volunteers, and nonviolent alcoholics. Results showed there were no significant differences in heart rate, RSA, or catecholamines. However, the significant inverse relationship between posture-elicited changes in RSA and heart rate present in the healthy volunteers was not found in perpetrators. These differences in the covariation between heart rate and RSA may represent differences in the neural regulation of heart rate and may be related to difficulties in controlling autonomic state.     

Anxiolytic properties of botanical extracts in the chick social separation-stress procedure

RATIONALE: The recent growth in sales of natural products labeled as dietary supplements in the United States has renewed scientific interest in the study of the therapeutic effects of multi-component botanical products. OBJECTIVES: This study sought to determine whether botanical extracts derived from the Rutaceae family, Acori graminei, the Magnoliaceae family, Alchemilla vulgaris and Primula veris, which had previously been identified in bioassays as having potential anxiolytic activity, were active in the chick social separation-stress procedure. METHODS: Eight-day-old chicks received IP injections of test articles 30 min before being tested in the presence of two social companions or in isolation for a 3-min observation period. Dependent measures were: a) latency to adopt a ventral recumbent posture to index sedation, b) number of vocalizations to index separation-distress and c) a composite pain score (comprised of footlift frequency and footlift duration in response to 50 microl of 0.10% formalin injected into the plantar surface of the foot) to index stress-induced analgesia. RESULTS: Proprietal extracts NPS00033 from the Rutaceae plant family and NPS00039 (Relora) from the Magnoliaceae plant family screened positive in this chick model without causing sedation. CONCLUSIONS: These results suggest that botanical extracts Relora and NPS00033 may be useful in modulating anxiety states.     

苗药道否纳栓剂的毒性学实验研究

目的研究苗药道否纳栓剂对家兔的毒性作用。方法对家兔分别采用单次及多次阴道给药,进行急性毒性和刺激性实验,观察其全身状态有无异常及阴道组织有无充血、红肿等。并进行皮肤变态反应实验。结果对家兔皮肤无刺激性,家兔给药前后全身状态无明显变化,刺激反应评分为0。结论苗药道否纳栓剂对家兔安全、无刺激性。     

Implications of incorrect determination of fetal sex by ultrasound

Objective: To assess the experiences of women following incorrect determination of fetal sex by ultrasound. Method: A 3-year prospective cohort study of 102 women with discordance between fetal sex determined by ultrasound scan and birth sex. Participants were interviewed using 2 structured pretested questionnaires. The first questionnaire was undertaken within 24 h of delivery. The women were followed up with a second questionnaire 6–9 months later. In-depth interviews were also carried out at this time. Results: Women who had received an incorrect determination of fetal sex by ultrasound experienced marital conflicts, domestic violence, negative perceptions of ultrasound, and a desire for reversal of tubal ligation. Conclusion: Incorrect determination of fetal sex by ultrasound has implications that can affect the mental and psychological health of the mother and the upbringing of the newborn.     

城市生活垃圾处理方案的选择

对选择城市生活垃圾处理方案进行了初步的探讨，指出在进行方案选择时，应对城市概况、技术、经济和财务、环境以及法律政策等5个方面的因素进行全面、详细的调查、分析和评价，并在此基础上进行总体评价，才能选择出最适宜的方案。     

三种国产乙型肝炎病毒基因荧光定量试剂检测结果分析

目的:探讨上海复星、深圳匹基、上海科华三种国产乙型肝炎病毒基因(HBV-DNA)荧光定量试剂的临床检测结果相互之间是否存在差异。方法:将相同的标本分别用三种国产HBV-DNA荧光定量试剂进行HBV-DNA荧光定量测定。然后再对检测结果进行对比,分析相互之间是否存在差异。结果:23例已知的慢性乙型肝炎患者标本,3例已知正常标本分别用三种国产HBV-DNA荧光定量试剂进行HBV-DNA定量检测,结果显示三种国产试剂的HBV-DNA定量检测结果相互之间差异小于一个数量级占91.4%,大于一个数量级小于二个数量级的占8.6%,经统计学分析差异无显著意义(P>0.05)。结论:上述三种国产HBV-DNA荧光定量试剂在同一套设备上的检测结果相互之间差异很小,有很好的准确度,它们的检测结果可以相互进行比较。     

Detection of glycosidic residues in carpal glands of wild and domestic pig revealed by basic and lectin histochemistry

Carpal glands are compound tubuloalveolar glands, located on the medial surface of the carpus. This study was carried out on samples from carpal glands of adult wild and domestic pigs of both sexes. We elucidated the glycosidic composition of carpal gland secretion in situ using traditional histochemical methods and lectin histochemistry. Some secretory cells exhibited an intense reaction with PAS in both wild and domestic pigs. Lectin histochemistry showed differences in the localization and composition of glycoconjugates secreted by carpal glands. A cytoplasmic positivity was revealed in the wild pig by the sequence sialidase-PNA and WGA, whereas in the domestic pig the reactivity was localized at the apical surface of some cells. LTA positive cells were found only in the carpal glands of the domestic pig.