全文获取类型
收费全文 | 47423篇 |
免费 | 2743篇 |
国内免费 | 954篇 |
专业分类
耳鼻咽喉 | 121篇 |
儿科学 | 433篇 |
妇产科学 | 580篇 |
基础医学 | 2887篇 |
口腔科学 | 637篇 |
临床医学 | 7470篇 |
内科学 | 11620篇 |
皮肤病学 | 298篇 |
神经病学 | 1334篇 |
特种医学 | 717篇 |
外国民族医学 | 4篇 |
外科学 | 3467篇 |
综合类 | 8387篇 |
现状与发展 | 3篇 |
一般理论 | 1篇 |
预防医学 | 4725篇 |
眼科学 | 433篇 |
药学 | 4771篇 |
88篇 | |
中国医学 | 1766篇 |
肿瘤学 | 1378篇 |
出版年
2024年 | 78篇 |
2023年 | 675篇 |
2022年 | 1484篇 |
2021年 | 2000篇 |
2020年 | 1932篇 |
2019年 | 1446篇 |
2018年 | 1564篇 |
2017年 | 1365篇 |
2016年 | 1617篇 |
2015年 | 1677篇 |
2014年 | 3960篇 |
2013年 | 3710篇 |
2012年 | 3510篇 |
2011年 | 3762篇 |
2010年 | 2715篇 |
2009年 | 2615篇 |
2008年 | 2464篇 |
2007年 | 2340篇 |
2006年 | 1917篇 |
2005年 | 1558篇 |
2004年 | 1216篇 |
2003年 | 1020篇 |
2002年 | 760篇 |
2001年 | 652篇 |
2000年 | 551篇 |
1999年 | 455篇 |
1998年 | 325篇 |
1997年 | 314篇 |
1996年 | 319篇 |
1995年 | 331篇 |
1994年 | 299篇 |
1993年 | 242篇 |
1992年 | 231篇 |
1991年 | 169篇 |
1990年 | 181篇 |
1989年 | 190篇 |
1988年 | 170篇 |
1987年 | 145篇 |
1986年 | 135篇 |
1985年 | 197篇 |
1984年 | 139篇 |
1983年 | 69篇 |
1982年 | 117篇 |
1981年 | 73篇 |
1980年 | 67篇 |
1979年 | 44篇 |
1978年 | 57篇 |
1977年 | 46篇 |
1976年 | 34篇 |
1974年 | 33篇 |
排序方式: 共有10000条查询结果,搜索用时 10 毫秒
51.
John R. Jarrett M.D. 《Aesthetic plastic surgery》1990,14(1):87-92
Immediate reconstruction of more than 1000 breasts was performed on high-risk patients on whom a prophylactic mastectomy was done. The mastectomy removes as much breast tissue as possible while leaving sufficient skin, and possibly the nipple-areola complex, to enable immediate reconstruction. The creation of symmetrical, well-balanced muscle pockets for the implant is the most important factor in producing satisfactory results in these cases. 相似文献
52.
53.
目的探讨肥胖患者下腹部手术采用Joel—Cohen切口对预防非感染性切口裂开的临床效果。方法选择切口部位皮下脂肪层厚达4—5cm的妇产科手术患者90例,随机分为观察组44例,采用Joel—Cohen切口;对照组46例,采用下腹正中直切口。观察切口愈合和脂肪液化情况。结果观察组切口甲级愈合率显著高于对照组(P〈0.01);脂肪液化切口裂开率显著低于对照组(P〈0.05)。结论脂肪组织厚达4—5cm以上下腹部手术切口,采用Joel—Cohen切口可以减少脂肪液化,切口愈合显著优于下腹直切口,值得临床推广应用。 相似文献
54.
55.
K. Toutouzas E. Tsiamis M. Drakopoulou A. Synetos J. Karampelas M. Riga C. Tsioufis D. Tousoulis E. Stefanadi C. Vlassis C. Stefanadis 《Diabetes & metabolism》2009,35(4):299-304
AimsLocal coronary and systemic inflammation is pronounced in patients with diabetes mellitus (DM). Intracoronary thermography detects local inflammation and C-reactive protein (CRP) is a marker of systemic inflammation. We investigated whether or not, in patients with DM, thermal heterogeneity of culprit lesions (CLs) correlates with that of non-culprit lesions (NCLs) and with systemic inflammation.MethodsWe included DM patients who had two angiographically significant lesions and were undergoing percutaneous coronary intervention. We measured the temperature difference (ΔT) between the lesion and proximal vessel wall.ResultsWe included 104 (n = 208 lesions) patients: 32 (n = 64 lesions) had DM and 72 (n = 144 lesions) were non-DM (control group). ΔT was increased in DM in both CLs and NCLs (CLs: DM = 0.12 ± 0.06 °C; no DM = 0.06 ± 0.04 °C; P < 0.01 versus NCLs: DM = 0.13 ± 0.08 °C versus no DM = 0.06 ± 0.05 °C; P < 0.01). Patients with DM had similar ΔT in CLs and NCLs (P = 0.49). A linear correlation was detected between heat production in all lesions and CRP (R = 0.45; P < 0.01), which was attributed to the correlation of ΔT in lesions of patients with DM and CRP (R = 0.32; P < 0.01). In lesions of patients with low CRP, a greater rate of discrepancy was found, as 100% of lesions in patients with DM versus 66.1% of lesions of patients without DM had a high ΔT in one or both lesions (P < 0.01).ConclusionIn patients with DM, local inflammatory activation is diffuse and correlates with systemic inflammation. However, low systemic inflammatory activation does not always predict an increase in local thermal heterogeneity. 相似文献
56.
57.
Objective To investigate the best way to control the blood sugar level during the perioperation of bone fracture patients with type 2 diabetes(T2DM).Methods Bone fracture patients with T2DM were randomly divided into three groups:continuous subcutaneous insulin infusion group(insulin aspart,group CSII,n=20),glargine treatment group(insulin aspart+insulin glargine,group GA,n=20),and NPH treatment(insulin aspart+rh-insulin,group NA,n=20).The levels of fasting plasma glucose(FPG)and the 2 hours postprandial glucose(2h PG),blood glucose fluctuation(BGF),insulin dosage(ID),good effective time(GET),incidence of hypoglycemia,dawn phenomenon and infection,average time of stitches removal(ATSR),average hospitalized length(AHL)of three groups were compared.Results FPG and 2hPG,ID in group CSII[(6.32±1.18)mmol/L,(7.72±1.53)mmol/L,(35.40±1.60)IU]and group GA [(6.25±0.88)mmol/L,(7.32±1.17)mmol/L,(36.20±0.80)IU]were significantly lower than those of group NA [(7.44±1.36)mmol/L,(8.52±0.76)mmol/L,(40.50±2.40)IU,all P<0.05],simulaneously,BGF,GET incidence of complications,ATSR,AHL of group CSII and GA were significantly lower than those of group NA(all P<0.05).There were not significant difference between group CSII and group GA.Compared with group CSII,group GA had less costs in-hospital and better practicability.Conclusion Both CSII and insulin glargine combined with insulin aspart can effectively,safely,rapidly and stablely control hyperglycemia.and might be the first choice to control blood sugar for bone fracture patients with T2DM in perioperation. 相似文献
58.
Two hundred and thirty pregnancies were studied in 196 diabetic women. Seven women with babies found to have major malformations had a higher median first trimester haemoglobin A1 (12.9%) than the median HbA1 (10.8%) in those with normal babies (p = 0.06). No relationship was found between the occurrence of minor malformations and first trimester maternal haemoglobin A1. Two of the seven congenital malformations were diagnosed antenatally at a time when therapeutic abortion could be offered. Expert antenatal ultrasound scanning should be offered to all pregnant diabetic women as poor glycaemic control at the time of conception and organogenesis, as evidenced by raised first trimester HbA1, predisposes to congenital malformation. 相似文献
59.
瑞芬太尼对老年患者麻醉诱导时血流动力学的影响 总被引:1,自引:0,他引:1
[摘要]目的观察瑞芬太尼全麻诱导对老年患者血流动力学的影响。方法60例ASAⅠ~Ⅱ级老年患者随机分成3组,F组、R1组和R2组,每组20例。F组静脉诱导用药:咪达唑仑0.05 mg·kg-1,芬太尼3 μg·kg-1,丙泊酚1 mg·kg-1,待入睡后注入维库溴铵0.1 mg·kg-1气管插管;R1组用瑞芬太尼1 μg·kg-1代替芬太尼;R2组用瑞芬太尼1.5 μg·kg-1代替芬太尼。观察诱导时血压、心率的变化,同时记录使用阿托品和麻黄碱情况。结果R2组最低血压(MAP1 )、最高血压(MAP2)明显低于其他两组(P<0.05=; R2组 最低心率(HR1)、最高心率(HR2)明显低于F组(P<0.05=。结论瑞芬太尼可以用于老年患者的全麻诱导,但在诱导时要密切注意血流动力学变化。 相似文献
60.
周现军 《邯郸医学高等专科学校学报》2003,16(5):395-396
目的 验证降糖灵 1号的降血糖作用。方法 以大、小白鼠为实验动物 ,分别与空白对照、高血糖对照及降糖甲片组和消渴丸组进行对照。研究降糖灵 1号对肾上腺素性和四氧嘧啶性高血糖的药理作用。结果 降糖灵 1号组除与消渴丸组对糖尿病差异无显著性意义 (P >0 0 5 )外 ,与其他各组差异均有显著性意义 (P <0 0 5 ,P <0 0 1)。结论 降糖灵 1号具有明显的降血糖作用 相似文献