全文获取类型
收费全文 | 6699篇 |
免费 | 429篇 |
国内免费 | 119篇 |
专业分类
耳鼻咽喉 | 157篇 |
儿科学 | 182篇 |
妇产科学 | 146篇 |
基础医学 | 663篇 |
口腔科学 | 244篇 |
临床医学 | 570篇 |
内科学 | 825篇 |
皮肤病学 | 96篇 |
神经病学 | 486篇 |
特种医学 | 380篇 |
外国民族医学 | 1篇 |
外科学 | 941篇 |
综合类 | 662篇 |
预防医学 | 437篇 |
眼科学 | 176篇 |
药学 | 602篇 |
4篇 | |
中国医学 | 239篇 |
肿瘤学 | 436篇 |
出版年
2024年 | 15篇 |
2023年 | 119篇 |
2022年 | 223篇 |
2021年 | 296篇 |
2020年 | 266篇 |
2019年 | 348篇 |
2018年 | 345篇 |
2017年 | 231篇 |
2016年 | 209篇 |
2015年 | 209篇 |
2014年 | 430篇 |
2013年 | 454篇 |
2012年 | 313篇 |
2011年 | 410篇 |
2010年 | 292篇 |
2009年 | 286篇 |
2008年 | 262篇 |
2007年 | 259篇 |
2006年 | 235篇 |
2005年 | 205篇 |
2004年 | 187篇 |
2003年 | 160篇 |
2002年 | 148篇 |
2001年 | 115篇 |
2000年 | 118篇 |
1999年 | 99篇 |
1998年 | 78篇 |
1997年 | 90篇 |
1996年 | 72篇 |
1995年 | 75篇 |
1994年 | 56篇 |
1993年 | 49篇 |
1992年 | 45篇 |
1991年 | 36篇 |
1990年 | 49篇 |
1989年 | 30篇 |
1988年 | 26篇 |
1987年 | 21篇 |
1986年 | 19篇 |
1985年 | 46篇 |
1984年 | 45篇 |
1983年 | 50篇 |
1982年 | 48篇 |
1981年 | 34篇 |
1980年 | 30篇 |
1979年 | 27篇 |
1978年 | 11篇 |
1977年 | 12篇 |
1976年 | 21篇 |
1975年 | 16篇 |
排序方式: 共有7247条查询结果,搜索用时 15 毫秒
71.
目的观察阴阳对刺呼吸补泻法治疗缺血性中风偏瘫运动步态踝关节的屈伸角度变化。方法将60例缺血性中风患者按随机数字表法分为对照组与治疗组,每组30例。对照组仅采用基础治疗,治疗组在基础治疗上予阴阳对刺呼吸补泻法治疗。于治疗前、治疗后28 d使用Lokomat全自动机器人步态评定系统对患者进行运动与静止踝关节的屈伸角度变化参数测定比较。结果治疗组治疗后足跟着地时,踝关节屈曲角度值、踝关节的屈伸角度最大值和活动度与对照组比较差异具有统计学意义(P0.05)。结论阴阳对刺呼吸补泻法可有效改善缺血性中风偏瘫运动,提高步行功能。 相似文献
72.
73.
目的:比较3种银杏叶制剂治疗冠心病心绞痛的成本-效果。方法:将103例符合诊断标准的冠心病心绞痛患者按照不同的用药方案分成A组(34例)、B组(35例)、C组(34例)。A、C组分别给予生产厂商及规格不同(2mL vs.5mL)的舒血宁注射液20mL、B组给予银杏达莫注射液20mL,3组均静脉滴注,qd,治疗14d后观察疗效,并进行成本-效果分析。结果:3组心绞痛改善总有效率分别为70.59%、91.43%、73.53%。成本分别为5207.86元、3575.46元、5065.06元,成本-效果比分别为7377.62、3910.60、6888.43。结论:与A、C组比较,B组治疗方案成本-效果比更优。 相似文献
74.
Faiza Al Kindi Madan Mohan Maddali Asim Al Balushi Hamood Al Kindi 《Clinical Case Reports》2022,10(7)
Bilateral bidirectional Glenn shunts are associated with the risk of developing pulmonary artery bifurcation stenosis, resulting in variable pulmonary blood flow to either lung. This could negatively impact the subsequent stages of the single ventricle palliation pathway. This report highlights the value of 4D flow sequence from the cardiac magnetic resonance imaging in demonstrating the pulmonary blood flow characteristics following a bilateral bidirectional Glenn procedure. Mapping the blood flow pattern and its quantification to each lung provide objective insights into the possible predisposing factors for the development of pulmonary bifurcation stenosis. 相似文献
75.
Oligodontia or absence of teeth such as the Canines is rare and is often accompanied with several other missing teeth. This condition may also be accompanied with morphological and growth related changes in the teeth and the maxillofacial complex. Complete agenesis of the permanent canines in the maxilla and the mandible is extremely rare and occurs in association with syndromic oligodontia. Non‐syndromic absence of canines however, is extremely rare and has only been reported twice. Studies have shown that the incidence of missing canines is more in females. This report describes a sporadic case of congenital absence of maxillary and mandibular bilateral canines. The patient reported to the clinic with a chief complaint of crowding and wanted alignment. On intra‐oral examination it was observed that the patient had all permanent canines missing with no prior history of extractions, crowding in both the arches and class I molars on both sides. With no other symptoms fixed orthodontic therapy was planned for the patient with premolars substituted for the canines. 相似文献
76.
Antioxidant properties of ursodeoxycholic acid 总被引:5,自引:0,他引:5
Lapenna D Ciofani G Festi D Neri M Pierdomenico SD Giamberardino MA Cuccurullo F 《Biochemical pharmacology》2002,64(11):1661-1667
We have investigated potential antioxidant properties of the clinically relevant bile acid UDCA, which reaches therapeutic concentrations up to 0.09 and 29 mM, respectively, in human plasma and bile. UDCA was an excellent scavenger of OHz.rad; generated by FeCl(3)-EDTA, H(2)O(2) and ascorbate in the deoxyribose oxidation test, showing IC(min) and IC(50) values of 0.02 and 0.2 mM, respectively, and a second-order rate constant for reaction with OHz.rad; of 2+/-0.1 x 10(10)M(-1)s(-1). Notably, the drug could enhance at 1.5 mM concentration the antioxidant capacity of human bile against OHz.rad;-induced deoxyribose oxidation. UDCA also showed antioxidant effects in the deoxyribose test performed with nonchelated iron ions, such as Fe(2+) plus H(2)O(2) (IC(min): 7 mM, IC(50): 20 mM) or Fe(3+) plus H(2)O(2) and ascorbate (IC(min): 0.3 mM, IC(50): 5 mM), and inhibited ferrozine-Fe(2+) and desferrioxamine-Fe(3+) complexes formation with IC(50) values of, respectively, 12 and 0.3 mM, indicating that the drug interacts more with iron(III) than with iron(II). Moreover, UDCA significantly inhibited phospholipid liposome peroxidation induced by the OHz.rad;-generating system FeCl(3)-EDTA, H(2)O(2) and ascorbate (IC(min): 0.75 mM, IC(50): 3 mM), and by peroxyl radicals generated in the aqueous phase by AAPH (IC(min): 8 mM, IC(50): 14 mM). UDCA, even at 25 mM concentration, was ineffective on the lipoperoxidation mediated by Fe(2+) alone, but at the same concentration counteracted significantly that by Fe(3+) plus ascorbate, further pointing to its preferential antioxidant interaction with iron(III).In conclusion, UDCA has direct antioxidant properties, which are especially relevant against Fe(3+)- and OHz.rad;-dependent biomolecular oxidative damage; such properties are evident at therapeutically relevant drug concentrations, suggesting that UDCA could act as an antioxidant in vivo. 相似文献
77.
Amitava Mitra Sandra Suarez-Sharp Xavier J.H. Pepin Talia Flanagan Yang Zhao Evangelos Kotzagiorgis Neil Parrott Satish Sharan Christophe Tistaert Tycho Heimbach Banu Zolnik Erik Sjögren Fang Wu Om Anand Shefali Kakar Min Li Shereeni Veerasingham Shinichi Kijima Andrew Babiskin 《Journal of pharmaceutical sciences》2021,110(2):594-609
78.
目的 探讨中性粒细胞与淋巴细胞比率(NLR)对非ST段抬高型急性冠脉综合征(NSTE-ACS)患者左主干或三支病变独立预测价值。方法 选取150例NSTE-ACS患者,根据冠脉造影结果分析NLR水平对NSTE-ACS患者左主干或三支病变的预测价值。结果 150例患者纳入最后的分析,通过受试者工作特征曲线分析,NLR水平预测NSTE-ACS患者左主干或三支病变的最佳截断值为2.58(曲线下面积0.72,特异性78.8%,敏感性61.2%)。150例NSTE-ACS患者中,NLR水平≥2.58的患者平均年龄较NLR<2.58的患者偏大(P=0.02),出现左主干或三支病变的比例明显升高(P<0.01)。logistic回归分析显示NLR≥2.58是对NSTE-ACS患者左主干或三支病变的独立预测因素(OR:4.73,95% CI:1.94~11.54,P<0.01)。结论 NLR≥2.58是预测NSTE-ACS患者左主干或三支病变的独立危险因素。 相似文献
79.
80.
Wangen Wang Yanran HePei Lin Yunfei LiRuifen Sun Wen GuJie Yu Ronghua Zhao 《Journal of ethnopharmacology》2014