Effect of Acupuncture Combined with Blood-letting by a Three-edged Needle on 50 cases of Bell's Palsy at the Acute Stage

Objective:To observe clinical effects of acupuncture combined with blood-letting by a three-edged needle for treating Bell's palsy of wind-heat syndrome at the acute stage.Methods:One hundred patients were randomly divided into a treatment group(50 cases) treated by acupuncture plus blood-letting and a control group(50 cases) treated by simple acupuncture.Four courses of treatments were given in both groups.The main symptoms and signs were observed and clinical effects evaluated with scores after one week,2...     

Molecular characterization of Korean Pepper mottle virus isolates and its relationship to symptom variations

The symptom variations among Korean Pepper mottle virus (PepMoV) isolates infecting pepper, tomato and potato were described and the cause of variations in relation to molecular variability were investigated. In addition, the entire genome of the 13 PepMoV isolates, collected from five provinces (Kyonggi, Chungnam, Gyeongnam, Jeonbuk and Jeonnam) in Korea, were determined and compared including the previously reported Korean-Vb isolate and 2 other PepMoV isolates isolated from America (CA and FL). Our results showed that the nucleotide sequence of all Korean isolates tested were nearly identical (98–99%) and only 94% similar to American isolates. In general, the complete nucleotide sequences and deduced polyprotein sequences indicated low genetic variation among isolates showing 0.1–3% nucleotide changes per site. However, based on ratio between nucleotide diversity values in nonsynonymous and synonymous position (dN/dS ratio) surprisingly, P1 and 6K2 genes showed relatively high nucleotide substitution ratio (0.8 and 1.0 nucleotide, respectively). When the 6K2 amino acid were aligned, there were 15 amino acid substitutions found in PepMoV-infected potato and only 1 amino acid change from two isolates of PepMoV-infected bell pepper. Interestingly, three isolates including isolate numbers 731, 205135 and 205136 that possessed different aa changes at 6K2 region also showed distinct symptom differentiation in indicator hosts and cosegregated in the phylogenetic analysis. These results further proved previous studies that P1 and 6K2 genes with other proteins might have some involvement on host specificity and pathogenicity.     

吊钟花配合红砂糖治疗输液外渗的临床疗效研究

目的 探讨吊钟花配合红砂糖治疗输液外渗的临床效果.方法 选择60例肿瘤科输液外渗的患者随机分为观察组和对照组各30例,对照组采用50％硫酸镁外敷,观察组采用吊钟花配合红砂糖进行外敷,观察两组患者治疗3d后的临床效果.结果 观察组患者总有效率93.3％,对照组患者总有效率60.0％,两组患者临床疗效比较差异有显著意义(P＜0.01).结论 吊钟花配合红砂糖治疗输液外渗临床效果满意,无不良反应,值得在临床中推广应用.     

高压氧联合阿昔洛韦治疗Bell麻痹效果观察

目的探讨高压氧联合阿昔洛韦治疗Bell麻痹的效果。方法我院2008年12月～2010年12月收治Bell麻痹71例,随机分为治疗组和对照组。治疗组37例予高压氧治疗每日1次;对照组34例施以针灸治疗,每日1次。两组均予呋喃硫胺20 mg和维生素B120.5 mg肌内注射每日1次,阿昔洛韦6～10 mg/（kg.d）静脉滴注每日1次,地塞米松3～5 mg/（kg.d）静脉滴注每日1次,疗程10 d。结果治疗组治愈率51.35%,总有效率100%;对照组治愈率29.41%,总有效率94.12%。两组治愈率比较差异有统计学意义（P〈0.05）。结论高压氧联合阿昔洛韦治疗Bell麻痹安全有效,可作为Bell麻痹治疗首选方案。     

徐润之和他的《松龄医铎》

徐润之，字松生，号松龄，浙江平阳人，清末民初浙南闽北名医。耽好道家之学，精内妇儿各科，尤长于温病，主张汇通中西医学，重视近代医学教育，曾创办中西医专门学校、松龄中医学校，著有《松龄医铎》《华佗疡科拾遗》。《松龄医铎》为医学丛书，8编7册，分别成书于1902～1911年间，统一刊行于1912年，现收于《温州文献丛书》重刊。其书各编内容、学术和编排结构等均有特点。     

Hypertriacylglycerolemia in the chick: Effect of estrogen on hepatic microsomal enzymes of triacylglycerol and phospholipid synthesis

Hepatic microsomal enzymes of triacylglycerol and phospholipid synthesis were investigated in chicks made hyperlipidemic by estrogen treatment. The total activities of two liver microsomal enzymes common to the triacylglycerol and phospholipid biosynthetic pathways, the fatty acid CoA ligase (AMP) (EC 6.2.1.3) and the sn-glycerol 3-phosphate acyl-CoA acyltransferase (EC 2.3.1.15), and an enzyme unique to triacylglycerol synthesis, the diacylglycerol acyltransferase (EC 2.3.1.20), increased 2.5–3.6-fold, as did total liver protein, relative to the activities and protein from controls. Upon subcellular fractionation, little change in the specific activities of these biosynthetic enzymes was observed. The microsomal marker activity NADPH cytochrome C reductase (EC 1.6.2.a) also increased proportionately with liver protein. However, the total activity of a phospholipid biosynthetic enzyme, diacylglycerol cholinephosphotransferase (EC 2.7.8.2) increased only 32% after a 5-day diethylstilbestrol course, while the specific activity of this enzyme decreased 40%. The total activity of succinic dehydrogenase (EC 1.3.99.1), a mitochondrial marker activity, increased only 22%, further demonstrating the differential effect of estrogen on hepatic enzyme activities. The augmentation of triacylglycerol synthesis may be mediated, in part, by increases in total activities of two enzymes common to the triacylglycerol and phospholipid synthetic pathways and/or by regulation at the diacylglycerol branch point of triacylglycerol and phospholipid synthesis.     

喜炎平与针灸联合西药治疗风热型面瘫31例临床观察

[目的]观察喜炎平与针灸联合西药治疗风热型面瘫疗效。[方法]采用前瞻性设计方法,对31例住院患者使用①喜炎平300mg+0.9%氯化钠250mL,1次/d,静滴。②针刺,取患侧阳白、四白、攒竹、太阳、下关、颧髎、迎香、牵正、地仓;水沟、承浆,对侧合谷穴,1次/d,留针30min。③局部按摩。④强的松30mg/d,一次顿服,7天后逐渐减量;甲钴胺0.5g/次,3次/d,口服;Vb1片20 mg/次,2次/d,连续口服2周。连续治疗15d为1个疗程。观测临床症状、面部表情肌及动作、不良反应。连续治疗2个疗程,判定疗效。[结果]痊愈23人,显效8人,治愈率73%,总有效率100%。[结论]喜炎平与针灸联合西药治疗风热型面瘫疗效满意,无副作用,值得推广。