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61.
目的探讨抗心磷脂抗体(ACA)与青光眼疾患的临床相关意义。方法对26例青光眼患者及11例非青光眼患者,采用抗心磷脂抗体酶免疫(ELISA)测定法,进行抗心磷脂抗体检测。结果青光眼组IgGACA与IgMACA值均比对照组高,有显著差异(P<0.05);其中开角型青光眼IgGACA与对照组之IgGACA值比较无显著差异(P>0.05);开角型青光眼IgMACA与对照组之IgMACA值比较有显著差异(P<0.05)。闭角型青光眼与对照组比较:IgGACA与IgM之ACA值比较均有显著差异(P<0.05)。结论青光眼病人的抗心磷脂抗体较高,预测可能产生视网膜静脉阻塞,需进一步追踪随访 相似文献
62.
目的评价睫状体冷冻术联合巩膜穿刺术在治疗绝对期青光眼中的应用。方法对绝对期青光眼47眼施行睫状体冷冻术联合巩膜穿刺术,观察术后3a内眼压变化。结果全部病例术后高眼压症都获缓解,对术后早期眼压反弹,本术较单纯施行睫状体冷冻术者控制眼压疗效好(P<0.01),且无副作用和并发症。结论睫状体冷冻术联合巩膜穿刺术是治疗绝对期青光眼更简便、安全、有效的手术选择。 相似文献
63.
减压阀引流术治疗新生血管性青光眼 总被引:26,自引:3,他引:23
为评价青光眼减压阀引流术治疗新生血管性青光眼,在视网膜血管性疾病、糖尿病、眼外伤所致的新生血管性青光眼29例29眼施行青光眼减压阀引流术,植入Ahmed减压阀20眼,Krupin减压阀9眼。青光眼控制标准为6mmHg≤眼压≤21mmHg,视功能保持或有所改善。结果:手术总成功率75.86%,眼压从术前平均52.56±14.51mmHg下降到20.15±13.26mmHg,平均随访17.83个月。有7眼在眼压正常后虹膜新生血管完全消退。术后3个月成功率79.31%,6个月成功率76.19%,1年成功率66.67%。主要手术并发症有前房导管口阻塞13.79%,浅前房10.34%,前房出血3.45%。结论:青光眼减压阀引流术治疗新生血管性青光眼获得较为满意的疗效,是目前值得推荐的治疗选择。 相似文献
64.
探讨发生于无晶体眼和人工晶体眼的青光眼的有效的手术治疗方法。方法:回顾分析1992年11月~1997年6月我院45例45眼发生于无晶体眼和人工晶体眼的青光眼的住院病例的临床资料。手术方法包括小梁切除术、睫状体冷冻术、青光眼减压阀植入引流术以及其他手术。结果:青光眼减压阀植入引流术控制眼内压优于睫状体冷冻术和小梁切除术,术后合并使用降眼压药物少于睫状体冷冻术后。结论:发生于无晶体眼和人工晶体眼的青光眼的治疗需根据临床情况考虑,青光眼减压阀植入引流术有较好的疗效 相似文献
65.
青光眼减压阀植入治疗无晶体眼和人工晶体眼青光眼的疗效 总被引:1,自引:0,他引:1
目的 :评价青光眼减压阀植入术治疗无晶体眼和人工晶体眼青光眼的疗效 ,探讨术后并发症和预防措施。方法 :回顾性分析19例 ( 2 0眼 )无晶体眼和人工晶体眼青光眼患者行青光眼减压阀植入术。其中 13眼行 Ahmed减压阀植入 ,7眼行 Krupin减压阀。结果 :术后一周平均眼压 1.93± 0 .69k Pa,95 %术眼眼压控制正常。平均随访 18.9± 6.9月的 14只术眼平均眼压 2 .4 0± 0 .4 7k Pa,64 .3 %术眼眼压控制正常。术后常见并发症有前房导管口阻塞、导管接触角膜、前房积血、低眼压等。结论 :青光眼减压阀植入术是治疗无晶体眼和人工晶体眼青光眼的较为有效的方法 ,但仍存在一定的并发症 相似文献
66.
Emilio Abecia Begoña Martínez-Jarreta Yolanda Casalod Blanca Bell Isabel Pinilla Francisco M. Honrubia 《International ophthalmology》1996,20(1-3):79-82
Purpose: To investigate possible associations between genetic markers and Primary Open-Angle Glaucoma (POAG). Methods: A number of genetic markers were typed in 84 unrelated patients with POAG and compared with a random sample of healthy individuals. The markers were Transferrin, Group Specific Component, G1m (1), G1m (2) and G3m (5) Allotypes, Adenylate Kinase, Adenosin Deaminase, Glyoxalase I and Acid Phosphatase and PCR-based markers HLA-DQA1 and D1S80. Results: No significant differences were found except the strong association between the group of POAG patients and Acid Phosphatase ACP*C allele (2 = 32.86; p < 0.0001). Conclusions: Since Acid Phosphatase gene is localized to chromosome 2p23, this result could be a first comprehensive step in the localization of POAG genes. 相似文献
67.
L. E. Pablo M. L. Gómez M. Pueyo T. Ramírez C. Torrón B. Melcón O. Ruiz F. M. Honrubia 《International ophthalmology》1996,20(1-3):11-14
Both filtering surgery with Mitomycin-C and diode laser cyclophotocoagulation have proved to be effective alternatives in cases of glaucoma with poor surgical prognosis. The right eyes of 40 pigmented rabbits were randomly divided into 2 groups: Mitomycin-C group underwent filtering surgery with application of 0.4 mg/ml of Mitomycin-C whereas the diode laser (DL) group received 15 applications of 1.8 J (1800 mW. 1000 ms) distributed in 270°. Mean IOP showed statistical differences in two periods between days 3–13 and 45–60 — Mann-Whitney U test — with a higher IOP lowering in the DL group. The comparison of IOP survival curves (Log-Rank test) was not significant p = 0.070809. Ocular hypertension, hyphema and inflammatory signs were higher in the DL group, both in short and long term, but in terms of statistical significance only ocular hypertension showed differences p = 0.00011717 - Fisher exact test. Microscopic examination revealed patent sclerostomies in 60% of the MMC group eyes with different grades of fibroblastic proliferation. In the DL group we observed necrosis of the sclieral stroma and of the pigmented and unpigmented ciliary epithelium, with signs of thermal coagulation of the ciliary stroma and of the stromal vasculature. We must point out that the treatment with laser has proved to be more effective although both treatments showed very acceptable IOP lowering until 2 months after the surgery. 相似文献
68.
We have described the epidemiological analysis of one aspect of the King's College Hospital computerised data base; namely initial intraocular pressure as an indicator of visual field loss. The methods involved the use of the four-fold table to determine sensitivity and specificity at different pressure levels. From these results (1) the changes in the pre and post test probability of field loss are calculated and (2) a sensitivity/specificity trade off curve or decision curve is constructed. In this way the optimal cut-off level or operating point for a population of specific type and composition can be determined. The factors concerned in decision making are always complex but such an approach allows a rational and quantifiable alternative to reliance on clinical impression and intuition. The results have significance in relation to decisions on the management of patients and on population screening programmes for glaucoma. 相似文献
69.
Orthograde fast axonal and nonaxonal transport through the optic disc was studied quantitatively and autoradiographically in albino rabbits during elevated (30 or 50 mmHg), normal (13–15 mmHg) and decreased (0–4 mmHg) intraocular pressure (IOP). In cases of intraocular hypertension up to 50 mmHg, autoradiographic findings of a disturbed orthograde fast axonal transport were seen in the optic disc within 3 hr. The blockage was relatively mild and uniform, and was distributed adjacent to the extension line of sclera. Despite this histological evidence of blockage, a quantitative analysis showed no statistically significant decrease in axonally transferred radioactivity within 3 hr. Decrease in the transferred material was evident at 6 hr, and the extent of decrease was mild (ca. 20% at the most prominent portion). In cases of moderate intraocular hypertension (30 mmHg) for 6 hr, a quantitative analysis showed no decrease in axonal transport. After 3–6 hr of intraocular hypotension (0–4 mmHg), papilledema did not develop and autoradiographically there was no accumulatjon of axonal components. Axonally transferred material remained quantitatively at the same level as in the control animals. Nonaxonal transport along the optic nerve was doubly enhanced in cases of intraocular hypertension up to 50 mmHg, and was reduced to one thrid at level of 0–4 mmHg. Filtration of intraocular fluid through the optic disc appears to be the largest component of the nonoxonal transport. 相似文献
70.
P A Weber 《Survey of ophthalmology》1981,26(3):149-153
Neovascular glaucoma is one the most difficult forms of glaucoma to treat successfully. Recent advances modifying filtration surgery can result in up to 77% success. Utilization of anterior and posterior segment photocoagulation can maintain an open angle in up to 80% of eyes when they are treated prior to angle closure by peripheral anterior synechiae. Destruction of the ciliary body can be performed more selectively utilizing argon and ruby lasers. This paper presents a rational approach to the management of neovascular glaucoma incorporating these recent advances. 相似文献