用竞争性酶联免疫吸附试验检测P_AIgG及其临床意义

应用竞争性酶联免疫吸附试验检测血小板表面相关IgG含量,并对71例各类血小板减少患者进行观察。原发性血小板减少性紫癜(ITP)92％以上自身抗体为P_AIgG,而其它病例则P_AIgG阳性率较低。     

复方中药毒性的数学模型

本文拙提出一种新的指标——LD50曲线，全面刻划复方中药各药剂量与毒性作用的内在联系。     

间接血凝试验诊断旋毛虫病

本文采用经Sephadex G-200层析后的旋毛虫幼虫抗原对实验感染旋毛虫大鼠和旋毛虫病人血清作间接血凝试验(IHA)。结果表明,20只大鼠感染后第16天全部出现阳性反应。9例旋毛虫病患者为阳性。本试验用于囊虫病、华枝睾吸虫病和健康人及正常大鼠均为阴性。检查本地区31只狗,阳性符合率为66.7％。     

儿童急非淋白血病第一次缓解期自体与异基因骨髓移植比较

HLA相合同胞供者的异基因骨髓移植(ALLOBMT)已在急非淋自血病(ANLL)缓解后的治疗中应用了一些年。儿童ANLLBMT后的无病生存率接近60％a对无适合供者的病人，自体骨髓移植(ABMT)是另一个可选的治疗手段。当前的研究已对类似病人的两种治疗疗效及毒性作用进行了比较，两组病人资料如表：     

Effect of Cu and Ni on Growth,Mineral Uptake,Photosynthesis and Enzyme Activities of Chlorella vulgaris at different pH Values

A pH dependent reduction in growth,pigment,ATP content,O2 evolution,carbon fixation,photosynthetic electron transport system,nutrient uptake(No3^- and NH4^ ) nitrate reductase,and ATPase activities and increase in K^ -efflux of Chlorella vulgaris was noticed following supplementation of Cu and Ni to the culture medium.PSⅡ was found to be more sensitive to both pH and metals than PS I.Though.nitrate reductase(NR)was more sensitive to both pH and metals,the ATP ase was however,more sensitive to metals but less sensitive to acidic pH.Acid pH was found to inhibit the nutrinent(NO3^-and NH4^ ) uptake and nitrate reductase in a non-competitive manner.The inhibition produced by the test metals alone was of non-competitive type for NO3^- uptake,nitrate reductase and ATPase and competitive for NH4^ uptake.Acidity not only inhibited the metabolic variables directly but also through facilitated uptake of metals and increased membrane permeability.A very low sensitivity of ATPase to acidic pH seems to be responsible for the survival of algae in acid environment.     

儿童巨细胞病毒感染的研究

对杭州市区0～4岁儿童进行了CMV及抗体检测,1297名中CMV阳性48名(3.70％),各年龄组阳性率高低不一;IgM、IgG、IgA抗体阳性率分别为0.69％、0.77％、2.00％。男性儿童CMV阳性率为2.89％,女性儿童阳性率为4.73％,两者差异无显著性(P>0.05)。健康儿童与患内科疾病的儿童配对分析表明,患病儿童CMV阳性率明显高于健康儿童(P<0.01)。PCR具有较高的敏感性及特异性,能检出血清学方法阴性的CMV感染,且方法简便、快速,适于临床推广应用。     

云南大理和吉林双辽人蚤狗株鼠疫菌栓形成能力试验

用鼠疫强毒菌株50012号、84003号,2.8×10~9个菌/ml,分别感染双辽人蚤狗株6批334只和大理人蚤狗株5批341只,均未形成菌栓。试验表明这两株人蚤不是鼠疫的有效传播媒介。