蝮蛇抗栓酶治疗类风湿关节炎153例

目的：探讨蝮蛇抗栓酶治疗类风湿关节炎的疗效。方法：类风湿关节炎病人１５３例（男性４３例，女性１１０例，年龄５１±ｓ８ａ，病程５．２±２．０ａ）采用蝮蛇抗栓酶１．０Ｕ溶于０．９％氯化钠注射液２５０ｍＬ中静脉滴注ｑｄ，３ｗｋ为一个疗程，结果，经２例疗程治疗，近期控制３７例（２４．２％），显效４３例（２８．１％）有效６６例（４３．１％）无效７例（４．６％），总有效率９５．４％，在改善晨僵，消肿止痛及关节     

血液中分离出星形奴卡菌1例报道

1　病历资料患儿 ,王某 ,男 ,9岁 ,主因咳嗽、发热于 2 0 0 1年 12月 2 9日来院就诊 ,以支气管肺炎收住院。查体 :双肺闻及痰鸣音及少量的水泡音 ,精神差。脉搏 96次 / min,呼吸 2 4次 / min,体温 38.6℃ ;血象 :WBC8.7× 10 9/ L,G0 .714,L 0 .2 0 5 ,M0 .0 81,入院后做血培养     

不同液体术前急性高容量血液稀释对深静脉血栓病人血液流变学的影响

Objective To investigate the effects of acute hypervolemic hemodilution (AHH) with different fluids on blood rheology in patients with deep vein (femoral and iliac) thrombosis. Methods Thirty ASA I or II patients aged 40-64 yr who had developed deep vein thrombosis in 48 h and were scheduled for embolectomy were randomly divided into 3 groups ( n = 10 each) ; group I normal saline (NS) ; group II 6 % HES 200/0.5 ( HES) ; group IE gelofusine (GEL). AHH was performed with normal saline, 6% HES or gelofusine infusion at 20 ml·kg-1 ·h-1 for 40 min. MAP, HR and SpO2 were monitored. Blood loss, volume of blood transfusion and fluid infused and urine output during operation were recorded. Anesthesia was induced with fentanyl 3-5 fig/kg, etomidate 0.15-0.30 mg/kg, propofol 1-2 mg/kg and succinylcholine 1-2 mg/kg and maintained with 2% isoflurane and propofol infusion at 5-8 mg·kg-1·h-1 and intermittent iv boluses of vecuronium. The patients were mechanically ventilated (VT 8 ml/kg, RR 12 bpm). PaO2 and PaCO2 were maintained within normal range. Venous blood samples were obtained before and after AHH for measurement of hematocrit (Hct), whole blood viscocity (WBV) at low or high shear rates, plasma viscosity, RBC aggregation and RBC deformation. RBC aggregation index and RBC deformation index were calculated. Results MAP and HR were stable in all patients. The amount of blood transfusion and fluid infused was significantly less in group HES and GEL than in group NS. The WBV at low or high shear rates in group HES and GEL, Hct in all 3 groups and RBC aggregation index in group HES were significantly decreased after AHH, but the RBC deformation index was significantly increased in group HES. Conclusion Colloid is better than crystalloid and HES is better than gelofusine in improving intraoperative hypercoagulability and sluggish blood flow.     

川芎嗪对急性脑梗死患者血液流变学的影响

目的：探讨川芎嗪对急性脑梗死患者血液流变学的影响。方法：将58例急性脑梗死患者随机分成两组，对照组采用基础治疗法，川芎嗪在基础治疗的同时加川芎嗪，观察两组治疗前后血液流变学指标的变化。结果：川芎嗪组治疗后高、低切变率下全血粘度、血浆粘度、红细胞变形指数及纤维蛋白原与治疗前比较有显著性差异（P＜0．05），其血液流变性改善程度明显优于对照组。结论：川芎嗪显著降低纤维蛋白原和血粘度，具有改善脑缺血，减轻临床症状的作用。     

实验家兔莱姆病血液学研究

本实验复制了莱姆病实验家兔模型，对血液生化23项进行了动态观察。结果表明，血液中谷丙转氨酶、γ-谷氨酰转肽酶、乳酸脱氢酶、谷草转氨酶、β-羟丁酸脱氢酶、磷酸肌酸激酶、胆固醇、尿素氮随病情加重而升高。葡萄糖、尿酸、磷随病情加重而减低。     

新生儿窒息后24小时血电解质变化（附72例分析）

新生儿窒息后由于机体内环境稳定被破坏,各种激素水平发生变化,水电解质亦随之发生一系列改变。了解窒息新生儿血电解质的变化,不仅可指导临床合理进行窒息复苏后的治疗,而且对提高窒息新生儿生存率,减少窒息合并症及神经系统后遗症具有重要意义。本文对我院1992～1993年收治的72例新生儿窒息后24小时的血电解质(钠、钾、氯、钙)进行了分析,报告如下。