抗磷脂抗体综合征的神经系统损害

抗磷脂抗体综合征(antiphospholipid antibody syndrome．APS)又称Hughes综合征．是一种以反复发生的血栓形成事件和流产为主要临床特征．并伴有血清中抗磷脂抗体存在的临床综合征。     

无骨折脱位型颈脊髓损伤的治疗

目的:探讨多节段无骨折脱位颈脊髓损伤的治疗。方法:多节段无骨折脱位型颈脊髓损伤21例,均行单开门颈椎管扩大减压成形术。采用JOA、Frankel分级及影像学进行疗效评价。结果:平均随访2年1个月,JOA评分术后改善率为37.81%,Frankel分级A→B 1例,B→C 7例,C→C 1例,C→D 10例,D→D 2例,D→E 4例。影像学检查提示颈椎生理曲度正常,未发现有再关门及不稳定现象。结论:单开门棘突重建颈椎管扩大成形术由于重建了颈后方韧带复合体,对于改善和维持颈椎的生理屈度、稳定性方面有重要的临床意义。     

散结镇痛胶囊联合康妇消炎栓治疗继发性痛经40例

继发性痛经是由于生殖系统病变如子宫内膜异位症、盆腔炎、子宫肌瘤（粘膜下肌瘤）、子宫颈或子宫腔粘连、生殖道畸形（子宫体过分前倾、后屈，阴道横隔）等机械性阻塞引起月经前后或在行经期间发生小腹疼痛或不适感的病症。发作时可出现阵发性小腹疼痛或胀痛，伴下坠感，严重者可出现放射到腰骶部、肛门、股内侧，甚至剧痛而晕倒，属妇科急症范畴。     

先天性无肛门合并脊髓膨出及双下肢畸形1例

【病例】男性 ,5h。因胎龄 30周 ,生活力低下 ,双下肢畸形入院。查体 :腰骶部可见一脊柱裂 (约 3cm× 3cm) ,伴脊髓膨出 ,周围见一束毛发 ,生殖器严重畸形 ,阴茎粗短 ,尿道下裂 ,膝关节异常粗大 ,不能伸直 ,双侧小腿细小 ,两侧踝关节发育不良 ,足内翻 ,足弓消失。未见肛门及瘘口。家族无类似病史。此母第 2胎无诱因流产 ,第 3胎早产。这次怀孕期间无感染 ,无乱用药及接触有毒物品。诊断 :① 先天性无肛门畸形 (CAM) ;② 脊柱裂合并脊髓膨出 ;③ 双下肢关节畸形 ;④ 尿道下裂 ;⑤ 早产儿。家长拒绝做染色体等系统检查 ,自动出院。讨论　CA…     

奥平栓配合冷冻治疗宫颈糜烂疗效观察

宫颈糜烂与癌前期病变及癌有着密切的内在联系。林巧稚报道，宫颈糜烂的癌发生率为0.73％，无糜烂癌变发生率为0.1％，二者相差7倍。因此。积极治疗宫颈糜烂是预防宫颈癌的重要措施。治疗的方法除局部用药，还有电灼、冷冻、激光和锥切等多种^[1]。我院在2000年1月之前，运用冷冻治疗宫颈糜烂收到一定疗效，但仍存在创面愈合慢，治疗时间长，     

采用超导光、中药熏蒸、抗生素联合治疗慢性前列腺炎的临床效果研究

慢性前列腺炎是男性常见的泌尿生殖系统疾病。在我国，社区居民发病率为5％-14．2％，前列腺炎占泌尿外科门诊疾病的33％。被WHO称为“21世纪病”。慢性前列腺炎以症状复杂多样化，病程迁延，顽固难愈和容易复发为特点，患者痛苦不堪，严重影响学习、工作和生活。本课题旨在评定这一联合疗法的临床疗效，探求一种安全性高、疗效好、副作用少的治疗方法，使这些患者尽早康复。     

常压及控制性降压下脊髓急性牵拉损伤比较研究

目的 评价控制性降压是否增加脊髓对牵拉损伤的易感性。材料与方法健康成年杂种犬6只，随机分为常压和控制性降压脊髓牵拉损伤组。观察常压及控制性降压水平下相同程度牵拉损伤后脊髓血流(SCBF)、体感诱发电位(SEP)、神经源性运动诱发电位(NMEP)改变的差异。结果 外周血有创动脉压(MABP)平均下降幅度为40．5％。经SSPS统计软件独立样本t检验，不同牵拉水平下，常压组及低压组的SCBF(％)、SEP波幅(Asep)(％)及NMEP波幅(％)无显著差异。结论 尼卡地平控制性降压不增加脊髓对牵拉损伤的易感性。     

腹腔镜肠粘连松解术

肠粘连是腹部外科手术术后的常见并发症，患常年忍受痛苦，传统的肠粘连手术往往只能解决一时之痛，其非但不能消除粘连，相反，术后必然还要形成新的粘连。腹腔镜肠粘连松解术能有效地解决这一难题。     

脊髓肿瘤漏诊分析(8例报告)

本院2003年6月～2005年10月共收治腰椎间盘突出患者213例，其中合并有脊髓肿瘤者8例。现总结分析如下。     

鞘内注射吗啡加可乐定对切口痛大鼠脊髓背角蛋白激酶A催化亚单位表达的影响

Objective To observe the effect of intrathecal clonidine plus morphine on expression of protein kinase A (PKA) catalytic subunit in the spinal dorsal horn in a rat model of incisional pain. Methods Eighty male Sprague-Dawley rats were divided randomly into five groups: sham group, control group, pre-incisional morphine 2.5 μg group, pro-incisional clonidine 5 μg group and preincisional morphine 2.5 μg plus clonidine 5 lag group (n=16). lntrathecal catheter and the model of incisional pain were pro-duced according to Yaksh and Brennan's described method respectively. Changes of pain behavior were assessed by mechanical with-drawal threshold (MWT) and thermal withdrawal latency(TWL). The expressions of PKA catalytic subunit in the spinal dorsal horn were assessed by immunohistochemical method and western blotting analysis. Results Compared with sham group, MWT and TWL in control group were decreased significantly at 2 h after incision (P<0.01) and the number of positive cells and protein expression of PKA catalytic subunit in the spinal dorsal horn were increased significantly in control group (P<0.01). Compared with control group, MWT and TWL in pre-incision morphine 2 μg plus clonidine 5 lag group were increased significantly at 2 h after incision (P<0.01) and the number of positive cells and protein expression of PKA catalytic subunit in the spinal dorsal horn were decreased significantly in pre-incision morphine 2 μg plus clonidine 5 μg group (P<0.01). However, MWT, TWL and the number of positive cells and pro-tein expression of PKA catalytic subunit in the spinal dorsal horn changed with no statistical significance in pre-incisional morphine 2.5 μg group and pre-incisional clonidine 5 μg group compared with control group. Conclusion lntrathecal clonidine significantly enhances the antinociceptive effect of intrathecal morphine in a rat model of incisional pain, which might be associated with inhibi-tion of the increased expression of PKA catalytic subunit in spinal cord.