喉返神经在发声中的机理探讨

对5只狗在全麻下，解剖出喉及颈部有关神经，分别切断后作不同神经衔接，于切断和衔接前后，用电刺激有关神经及肌肉，观察声门及发声改变，分析了各项实验结果，并探讨其在发声中的机理和临床意义。     

Functional Maturation of Neuroendocrine Gonadal Axis is Altered by Specific Phase Relations of Circadian Neurotransmitter Activity in Japanese Quail

The preset study was designed to ascertain the effects of temporal relationship of circadian neural oscillations on puberty attainment and reproductive growth of Japances Quail,Coturnix coturnix japonica,Serotonin and dopamine precursors(5-hydroxytryptophan,5-HTP and L-dihydroxyphenylalanine,L-DOPA,5mg/100g body weight)were injected daily,8and 12h apart in two groups of one-day ld chick,while cotrols received two daily injections of normal saline.Weekly/biweekly observations(body weight,cloacal gland size,testicular volume and activity,ovarian follicular diameter and rate of egg production)were made until 9 weeks of age,when the experiment was terminated.Results indicate that 8 h relationship completely suppressed gonadal growth even under long photoperiod(LD16:8),while a 12 h relationship induced precocious sexual maturity and increased the rate of reproductin(spermatogenesis and egg production).It is concluded that circadian phase relationship of serotonergic and dopaminergic activity may not only determine the onset of reproduction in this pultry species,but may also alter the rate of reproduction possibly by affecting photoperiodic mechanism of reproductive regulation.     

椎管内原发性恶性骨神经鞘瘤二例报告

良性神经鞘瘤报道尚多，但恶性神经鞘瘤则较为罕见，作者曾手术治疗椎管内恶性骨神经鞘瘤2例，现报告如下。     

颈静脉孔区神经鞘瘤的伽马刀治疗

颈静脉孔区神经鞘瘤发病率较低。手术切除是过去首选的治疗方法,但肿瘤全切除率极低,且手术后多数病人后组颅神经障碍的症状有所加重或产生面瘫。80年代以前文献报道手术后死亡率在9.1％～16.1％。伽马刀治疗颈静脉孔区神经鞘瘤是十多年来开展的新项目,但临床报道很少。我院对8例病人进行伽马刀治疗,结合随访情况作一总结。     

糖尿病性神经病变的其它药物治疗

糖尿病性神经病变的治疗颇为棘手,以往常用维生素B_1、B_6、B_(12)等,收效甚微。近年来发现一些“老药”用于治疗本病,取得显著效果,现介绍如下。1 利多卡因Kastrup 用随机双盲交叉研究观察静滴利多卡因(5mg/kg)对糖尿病性神经病变的作用,发现给药后症状明显改善。作者认为利多卡因可能象治疗心律失常一样,由于切断了异常的神经冲动线路而改善症状。晚     

耳-体穴电针对去除部分盆神经家兔膀胱机能的影响

本文采用部分去除家兔膀胱的盆神经支配,使其产生可逆性尿潴留状态,观察耳—体穴电针对膀胱机能的影响。结果说明因神经损伤产生的尿潴留很难在短期内治愈,而针灸治疗可减轻症状,似可促进早日康复。     

辛伐他汀对缺血性脑卒中患者血小板功能的影响

他汀类药物为羟甲基戊二酰辅酶A（HMG-CoA）还原酶抑制剂.近年来动物实验证实：他汀类药物通过保护血管内皮细胞、抑制炎症反应和抗氧化作用等途径起到了神经保护作用.而他汀类药物对血小板功能的影响报道较少.我们应用不同剂量辛伐他汀（商品名舒降之,杭州默沙东制药有限公司产品）治疗急性期脑梗死患者98例,动态观察了血小板α颗粒膜蛋白CD62P及血小板计数的变化,现报道如下.