补阳还五汤对大鼠脑皮层神经元生长的影响

目的观察含补阳还五汤的药物血清对体外培养大鼠脑皮层神经元生长的影响,为补阳还五汤治疗缺血性脑损伤提供实验依据。方法以体外培养新生SD乳鼠大脑皮层神经元为观察对象,采用四唑盐(MTT)比色法测定细胞生长情况。观察含药血清对常规培养及在缺氧状态下神经元生长的影响。结果补阳还五汤对常规培养及在缺氧条件下培养的神经元有显著促进生长作用,与空白血清组比较有显著差(P<0.05)。结论大鼠以补阳还五汤灌胃给药后,其血清中的药物成份有促进体外培养神经元细胞生长的作用。     

异丙酚静脉全麻复合硬膜外腔阻滞麻醉期间CO2气腹对血流动力学和氧耗的影响

OBJECTIVE: To investigate the effects of intraperitoneal CO2 insufflation on the hemodynamics, oxygen consumption (VO2) and carbon dioxide production (VCO2) during intravenous anesthesia with propofol in combination with epidural block. METHODS: Intratracheal intubation was performed after rapid induction of anesthesia and mechanical ventilation was given. Maintenance of anesthesia was achieved using continuous intravenous propofol infusion (2 mg/kg/h) ?N2O inhalation and intermittent epidural administration. Indices of hemodynamics and respiratory function were collected 5 min before induction, 1 min before CO2 insufflation, and 5, 10, 20, 30, 40, 50, 60 min after the start of insufflation and 5 min after the termination of insufflation. RESULTS: The mean arterial pressure (MAP), heart rate (HR), end-tidal PCO2 (P(ET)CO2), VO2 and VCO2 1 min before insufflation were markedly reduced(P<0.01), compared with those recorded before induction. MAP and HR did not undergo any conspicuous changes during CO2 insufflation and 5 min after insufflation termination. Compared with that 1 min before insufflation, PETCO2 was significantly increased 20 min after the start of insufflation (P<0.01), and subsequently carried on the increase though of a lesser scale. VO2 and VCO2 gradually rose after the start of insufflation, and VO2 presented a significantly elevation (P<0.01) 10 min after the insufflation while VCO2 did not show this marked increase(P<0.05) till 20 min after the insufflation in comparison with the levels before insufflation. Subsequently, VO2 continued to rise and VCO2 also retained the increase but of smaller magnitude. CONCLUSION: Intravenous propofol anesthesia combined with epidural block assisted by well-managed excessive ventilation before insufflation can alleviate the adverse effects of CO2 insufflation on respiratory and circulatory systems.     

充血性心力衰竭病人甲状腺激素的变化及其意义

目的：观察充血性心力衰竭病人血清T3、T4水平变化及其与心脏功能之间的关系。方法：采集充血性心力衰竭病人的血标本。用放射免疫方法测定血清T3、T4水平。结果：与正常对照组相比充血性心力衰竭病人血清T3水平显降低，并与患的心脏功能有密切的关系。结论：充血性心力衰竭病人血清T3水平显低于正常人水平，其机制可能是由于T4向T3转化速度减慢所致。较低的血清T3水平可以作为充血性心力衰竭病人不良预后的指标之一。     

古代中医书名趣谈

历代中医古籍繁多,其书名也多种多样,细探内涵之意,别有一番雅趣。现就笔者有限藏书,依照书名特点,作一简述。●用典如中医四大经典之一———医圣张仲景的代表作《金匮要略》。“金匮”二字源自《周书.金縢》。周武王病重之际,其弟在神像前虔诚地为他祈祷,并表示心甘情愿替代周武王去死。后来史官便把这篇祈祷辞非常珍重地保存于用金字封藏起来的“金縢之匮”中。可见,《金匮要略》寓有宝贵资料之意。再如清代的《痘麻绀珠》,书名取自宋代米胜的《绀珠集》。传说张燕公有绀珠,见之则能记事不忘。《绀珠集》就相当于现在的“备忘录”,无疑,…     

房定亚以四神煎治疗急性膝关节炎经验

房定亚老师系中国中医科学院西苑医院主任医师,行医40余年,坚持理论与实践相结合、中西医相结合、辨病与辨证相结合的治疗原则,临床疗效颇佳。房师对疾病的认识有独到的见解、治疗上有丰富的经验。现总结并介绍其治疗急性膝关节炎的经验如下。急性膝关节炎是风湿免疫科临床常见病、多发病。临床表现膝关节红、肿、热、痛、僵硬、活动障碍。本病多见于骨性关节炎、类风湿性关节炎等疾病。流行病学统计在60岁以上的人群中,放射学显示有膝骨关节炎改变征象的占85%,故膝关节炎对患者身体和活动能力均可造成较大影响。1中医学对本病的认识中医对…     

氧苏辅助治疗精神分裂症的疗效观察

目的探讨氧苏辅助治疗精神分裂症的临床疗效及不良反应。方法将66例住院精神分裂症患者随机分为维思通合并氧苏治疗组(A组)与维思通治疗组(B组)，并对临床资料进行分析，在治疗前、第2、4、6周末分别应用简明精神病评定量表(BPRS)和副反应量表(TESS)，评定其临床疗效及不良反应。结果两者在疗效上有显著性差异，不良反应无显著性差异。结论氧苏治疗对精神分裂症有良好的辅助治疗作用。     

中医药防治高血压病的特色

心脑血管疾病是中老年人健康的主要杀手之一,高血压病就是杀手背后的黑手.如何发挥中医药在防治高血压病中的特色和优势,是我们中医药工作者义不容辞的任务.中医治疗高血压的特色主要有以下几点:     

老年人氧保健和老年病的氧疗

Woiwitz等在1969年测出:老年人每增加1岁,动脉血氧分压平均降低3mmHg。根据人体生理的一般生长发育变化情况,大体上25岁以前为发育阶段,25～44岁为成熟阶段,45岁以后进入衰退阶段。     

肿瘤乏氧组织显像剂的研究进展

乏氧组织显像剂能选择性地滞留在乏氧组织或细胞中,通过无创性的核医学正电子发射体层摄影术/单光子发射计算机体层摄影术可评价实体肿瘤缺氧状态.一些显像剂适宜进行乏氧显像并能很好地反映肿瘤乏氧及其程度等情况,这些信息在肿瘤的临床诊断决策中起到重要作用.