中国健康人群正常心率范围的调查

目的：调查中国健康人群心率的分布及其性别,年龄差异,评估传统的正常心率标准。方法：采集5360例（男3614例,女1746例）健康人心电图,并按性别分为5个年龄组,计算各年龄组心率的中位数,上限和下限值。结果：男性心率中位数为67－68次／min,随年龄波动很小;女性心率的中位数为67－73次／min,随年龄增长呈下降趋势。年轻女性心率的中位数,上限和下限值均比同年龄组男性快5－6次／min,性别差异随年龄增长而减低或消失。15％的人群心率小于60次／min。男性心率下限值为51次／min,而女性心率下限值50岁以前约为55次／min,50岁以后为51次／min。男,女心率上限值均随年龄增长逐渐降低,但在50岁以后再次增快;总体人群的心率上限值为95次／min,结论：传统的正常心率标准确有必要作适当调整。     

间接白蛋白钴结合试验测定血清缺血修饰白蛋白

目的:采用国产试剂盒,利用间接白蛋白钴结合试验对血清缺血修饰白蛋白(IMA)进行自动分析测定.方法:用HITACHI公司7600-020全自动生化分析仪和国产试剂盒,用间接白蛋白钴结合试验测定100名正常人血清IMA含量.结果与结论:本法批内变异1.31%,批间变异3.30%,最低检出限10～18 ku/L,线性范围14～200 ku/L,白蛋白质量浓度在20～50 g/L范围内时与IMA浓度呈线性关系,Y=4.58X-30.8(r=0.999,P＜0.01).本法测定血清IMA正常值范围＜70.0 ku/L.     

健康人脉冲振荡肺功能测定正常值范围探讨

目的 对健康人进行脉冲振荡(impulse oscillometry system,IOS)肺功能测定,探讨IOS肺功能的正常值范围.方法 随机选取257例没有疾病、无吸烟史的健康人.先进行常规肺功能检测,再对常规肺功能正常者91例用脉冲振荡(impulse oscillometry system,IOS)法进行肺功能测定,按照欧洲呼吸协会公布的测定要求执行;测定指标包括呼吸总阻抗(Zrs),5赫兹时呼吸阻力(R5),20赫兹时呼吸阻力(R20),5赫兹时呼吸电抗(X5),20赫兹时呼吸电抗(X20),中心阻力(Rc),周边阻力(Rp),以上数据的单位为KPa/(L. s);弹性阻力等于惯性阻力时的响应频率(Fres),单位为L/s;弹性阻力(Ers),Fres与X5和坐标原点所围成的面积AX,这两项的单位均为KPa/L.结果 经统计学处理,求得中位数与95%可信区间,从统计分析中得出Zrs、R5、R20、X5、X20、Rc、Rp、Fres、Ers与AX的参考值,但由于各地区的环境不同,参考值可能不尽相同,所以各地区应该建立自己的参考值.结论 IOS肺功能测定为患者与医生都提供了方便,值得推广与应用.     

上海市崇明地区成年人鼻阻力和鼻声反射的初步研究

目的 通过对上海市崇明地区健康成年人鼻通气功能的客观测定,建立崇明地区健康成年人鼻阻力(RM)、鼻声反射(AR)等参数的正常参考值范围,并初步分析两者相关性.方法 采用NR6鼻阻力计采集受试者经鼻压差为150Pa下前端测量的单侧鼻腔吸气阻力(Ri)、呼气阻力(Re)等数据,通过计算机软件计算后得出单侧总阻力(RI)、双...     

杭州地区2～6岁健康儿童血清垂体-甲状腺轴激素正常参考范围调查

用化学发光法检测592名杭州地区2～6岁健康儿童的血清TSH、T3、T4、FT3、FT4浓度并作统计分析,得出总人群的正常参考范围为:TSH 1.09～4.60 mIU/L,T3 1.17～1.95μg/L,T4 57.43～99.60μg/L,FT3 5.35～7.50 pmol/L,FT4 13.96～19.70 pmol/L.不同年龄、不同性别间比较,差异无统计学意义(P＞0.05).

Abstract：

Serum concentrations of TSH, total and free thyroxine, and total and free triiodothyronine in 592 healthy children aged 2-6 years were determined by means of ADVIA Centaur. The normal reference ranges were calculated. The reference ranges of TSH, T3, T4, FT3, and FT4 were 1.09-4.60 mIU/L, 1.17-1.95 μg/L,57.43-99.60 μg/L, 5.35-7.50 pmol/L, 13.96-19.70 pmol/L, respectively. There was no significant difference in the interval of thyroid hormones between males and females as well as among different age groups.     

齐齐哈尔地区血液流变测定参考值

目前血液流变学检查对诊断中风、动脉硬化、冠心病、高血脂等具有不可忽视的临床诊断价值。但我国地域辽阔,南北气侯温差甚大,因此设定本地区血流变各项参数的参考值,对临床的诊断和治疗是十分必要的。我们在健康体检中经过检测,提出了本地区的参考范围,现报告如下。     

血栓与止血的检测

血栓与止血的实验室检测，必须掌握常用检测项目，了解新的分子标志物检测项目的原理、参考值和临床意义。     

老年人静脉血细胞分析参考值范围的调查研究

Objective To establish the reference range of venous blood cells of healthy aged people by means of investigation on the reference range of venous blood cells of healthy adults and the aged.Methods The parameters of 3302 venous blood samples from the healthy adults and the aged were analyzed by applying SymexKX-21N hematology analyzer,and the test results were statistically analyzed with SPSS10.0 software.Results The reference range of the healthy aged people(males and females):WBC(3.57-9.00)×109/L and(3.52-8.39)×109/L;RBC(3.78-5.42)×1012/L and (3.44-4.83)×1012/L;hemoglobin(Hb)121.40-168.10 and 107.90-147.90 g/L;hematocrit(HCT)36.62%-49.18% and 32.82%-44.03%;mean corpuscular volume(MCV)85.10-100.60 and 84.70-100.60 fL;mean corpuscular hemoglobin(MCH)28.54-34.48 and 28.20-34.10 pg;mean corpuscular hemoglobin concentration(MCHC)322.00-357.00 and 320.00-352.00 pg/L;coefficient of variation of red blood cell distribution width(RDW-CV)12.13%-15.10% and 10.20%-17.12%;platelet(PLT)(70.00-240.00)×109/L and(77.00-262.00)×109/L;mean platelet volume(MPV)9.77-15.37 and 9.51-15.55 fL;platelet distribution width(PDW)11.44%-27.77%;platelet hematocrit(PCT)1.10-2.73 and 1.13-2.99 mL/L;large platelet ratio(P-LCR)24.35%-70.14%.The differences of the parameters(WBC,RBC,Hb,HCT,MCHC,PLT and PCT)were statistically significant between senile males and senile females(P＜0.01),while the other parameters weren't(P＞0.05);the differences of parameters(WBC,MPV,PDW and P-LCR)were not significant between adults and the ageds(P＞0.05),while the other parameters were(P＜0.05).There were also significant differences(P＜0.05)between the test results and the reported date about the blood cell parameters of adults and the ageds.Conclusion The reference range of the healthy ageds is different from that of adults;therefore it is necessary to establish the laboratory reference range of venous blood cells of the elderly in this region scientifically and rationally.     

老年人静脉血细胞分析参考值范围的调查研究

Objective To establish the reference range of venous blood cells of healthy aged people by means of investigation on the reference range of venous blood cells of healthy adults and the aged.Methods The parameters of 3302 venous blood samples from the healthy adults and the aged were analyzed by applying SymexKX-21N hematology analyzer,and the test results were statistically analyzed with SPSS10.0 software.Results The reference range of the healthy aged people(males and females):WBC(3.57-9.00)×109/L and(3.52-8.39)×109/L;RBC(3.78-5.42)×1012/L and (3.44-4.83)×1012/L;hemoglobin(Hb)121.40-168.10 and 107.90-147.90 g/L;hematocrit(HCT)36.62%-49.18% and 32.82%-44.03%;mean corpuscular volume(MCV)85.10-100.60 and 84.70-100.60 fL;mean corpuscular hemoglobin(MCH)28.54-34.48 and 28.20-34.10 pg;mean corpuscular hemoglobin concentration(MCHC)322.00-357.00 and 320.00-352.00 pg/L;coefficient of variation of red blood cell distribution width(RDW-CV)12.13%-15.10% and 10.20%-17.12%;platelet(PLT)(70.00-240.00)×109/L and(77.00-262.00)×109/L;mean platelet volume(MPV)9.77-15.37 and 9.51-15.55 fL;platelet distribution width(PDW)11.44%-27.77%;platelet hematocrit(PCT)1.10-2.73 and 1.13-2.99 mL/L;large platelet ratio(P-LCR)24.35%-70.14%.The differences of the parameters(WBC,RBC,Hb,HCT,MCHC,PLT and PCT)were statistically significant between senile males and senile females(P＜0.01),while the other parameters weren't(P＞0.05);the differences of parameters(WBC,MPV,PDW and P-LCR)were not significant between adults and the ageds(P＞0.05),while the other parameters were(P＜0.05).There were also significant differences(P＜0.05)between the test results and the reported date about the blood cell parameters of adults and the ageds.Conclusion The reference range of the healthy ageds is different from that of adults;therefore it is necessary to establish the laboratory reference range of venous blood cells of the elderly in this region scientifically and rationally.