全文获取类型
收费全文 | 648篇 |
免费 | 49篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 116篇 |
儿科学 | 24篇 |
妇产科学 | 4篇 |
基础医学 | 32篇 |
口腔科学 | 20篇 |
临床医学 | 81篇 |
内科学 | 85篇 |
皮肤病学 | 4篇 |
神经病学 | 15篇 |
特种医学 | 8篇 |
外科学 | 213篇 |
综合类 | 64篇 |
预防医学 | 12篇 |
药学 | 18篇 |
中国医学 | 1篇 |
肿瘤学 | 7篇 |
出版年
2024年 | 3篇 |
2023年 | 14篇 |
2022年 | 17篇 |
2021年 | 31篇 |
2020年 | 54篇 |
2019年 | 25篇 |
2018年 | 25篇 |
2017年 | 26篇 |
2016年 | 26篇 |
2015年 | 29篇 |
2014年 | 40篇 |
2013年 | 33篇 |
2012年 | 39篇 |
2011年 | 35篇 |
2010年 | 22篇 |
2009年 | 35篇 |
2008年 | 26篇 |
2007年 | 30篇 |
2006年 | 20篇 |
2005年 | 20篇 |
2004年 | 20篇 |
2003年 | 22篇 |
2002年 | 15篇 |
2001年 | 13篇 |
2000年 | 6篇 |
1999年 | 6篇 |
1998年 | 11篇 |
1997年 | 9篇 |
1996年 | 3篇 |
1995年 | 8篇 |
1994年 | 4篇 |
1993年 | 1篇 |
1992年 | 6篇 |
1991年 | 6篇 |
1990年 | 3篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1986年 | 1篇 |
1985年 | 4篇 |
1984年 | 2篇 |
1983年 | 4篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1978年 | 2篇 |
1977年 | 1篇 |
1972年 | 1篇 |
排序方式: 共有704条查询结果,搜索用时 15 毫秒
691.
Suman Sarkar P Shashi Anil Kumar Paswan R.P. Anupam S. Suman Surya Kumar Dube 《Indian Journal of Critical Care Medicine》2010,14(4):185-187
Purpose:
To study the feasibility of using the pro-seal laryngeal mask airway (LMA) for airway maintenance during bronchoscopic-guided percutaneous tracheostomy.Materials and Methods:
Observational study of 60 patients in a 16-bed intensive care unit. The patient’s tracheal tube was exchanged for a pro-seal LMA before undertaking percutaneous tracheostomy.Results:
Inspiratory pressure and tidal volumes achieved during the procedure were recorded. The median peak inspiratory pressure was 25 (standard deviation 4.4) cm H2O. There was no loss of tidal volume in 30 patients, a loss of less than 100 mL/breath in 27, and loss of more than 100 mL in 3 patients. A pro-seal LMA successfully maintained the airway and allowed adequate ventilation during per-cutaneous tracheostomy in all 60 patients. In all patients, fiber optic bronchoscopy through the pro-seal LMA provided a clear view of the cords and trachea and there was no laryngeal or tracheal soiling at any stage of the procedure.Conclusion:
The pro-seal LMA provides a reliable airway and allows effective ventilation during percutaneous tracheostomy. The passage of a fiberscope through the pro-seal LMA and glottis is easy and provides a clear view of the upper trachea. 相似文献692.
David B. Seder Kiwon Lee Celine Rahman Nirmala Rossan-Raghunath Luis Fernandez Fred Rincon Jan Claassen Errol Gordon Stephan A. Mayer Neeraj Badjatia 《Neurocritical care》2009,10(3):264-268
Introduction We evaluated the effects of a change from routine surgical tracheostomy (ST), performed primarily by ENT surgeons, to bedside
percutaneous tracheostomy (PT) performed by neurointensivists.
Methods The first 67 PT procedures performed by neurointensivists were retrospectively reviewed, and compared with 68 consecutive
ST procedures performed during the previous year. Demographics, severity of illness, procedural complications, incidence of
ventilator-associated pneumonia (VAP), duration of mechanical ventilation (DMV), length of stay (LOS), and hospital charges
were evaluated.
Results Age, race, gender, neurological diagnoses, comorbid illnesses, and Glasgow coma scale on admission and the day of tracheostomy
were similar. Procedural complications occurred in 8% of PT patients and 9% of ST patients, including clinically significant
bleeding, transient loss of the airway, ICP rise requiring treatment, or acute lung injury (P = 0.3). PT was performed earlier than ST (median [interquartile range] ventilator day 8 [4–11] vs. 12 [8–18], P = 0.001). Median DMV was shorter in the PT cohort (19 [10–27] vs. 24 [16–33] days, P = 0.02), as was median ICU LOS (15 [9–21] vs. 19 [12–27] days, P = 0.01). ICU charges (US dollars) were lower in the PT cohort (median $123,404 vs. $156,311, P = 0.01). Trends toward less VAP, shorter hospital LOS, and lower total hospital charges among patients receiving PT did not
achieve significance.
Conclusions PT performed by neurointensivists was safe compared to ST. Timely PT by neurointensivists may offer significant advantages
in terms of ventilator weaning, ICU LOS, and the cost of care. 相似文献
693.
目的:探讨纤维支气管镜引导下经皮扩张气管切开术在口腔颌面外科的应用价值。方法:选择因手术需要行预防性气管切开的口腔颌面外科患者60例,随机分为3组(n=20):经典手术气管切开组(A组)、经皮扩张气管切开组(B组)、纤维支气管镜引导下经皮扩张气管切开组(C组)。观察并记录3组的气管切开操作时间、出血量、一次性置管成功率、血氧饱和度(SpO2)变化和并发症的差异。采用SPSS 17.0软件包对数据进行统计学分析。结果:与经典手术A组相比,B组和C组在气管切开中的操作时间显著缩短,出血量和并发症减少,一次性置管成功率显著提高(P<0.05)。与B组相比,C组在操作时间上显著减少,一次性置管成功率显著提高(P<0.05)。结论:纤维支气管镜引导下经皮扩张气管切开术安全有效,在口腔颌面外科手术中有较高的应用价值。 相似文献
694.
Niskanen M Purhonen S Koljonen V Ronkainen A Hirvonen E 《Acta anaesthesiologica Scandinavica》2007,51(4):509-513
A 45-year-old man needed emergency tracheostomy and cranioplasty. He was intubated with a cuffed oral polyvinylchloride endotracheal tube and ventilated with 100% oxygen before tracheal incision. During opening of the trachea using diathermy, a popping sound was heard and flames originating from the tracheal incision were observed. The endotracheal tube was charred and its lumen had melted. Immediately after the incident, bronchofibroscopic examination revealed inhalation injury. After remaining for 8 weeks in hospital, the patient was transferred to a health care centre, where he was found dead in his bed. 相似文献
695.
Bedside percutaneous dilatational tracheostomy (PDT) has become an accepted method for securing airways in patients requiring prolonged ventilatory support. Repeat PDT in patients who have had a tracheostomy earlier is considered a relative contraindication as a result of distorted anatomy. Three case series have been reported supporting the safety of repeat bedside PDT in experienced hands, but there is no previously published data regarding repeat PDT in awake and unintubated patients. We report a case in which a repeat PDT was done on an awake 20-year-old female patient with cerebral palsy and kyphoscoliosis admitted owing to pneumonia and respiratory failure. This facilitated tracheal toilet in this patient without resorting to general anaesthesia and mechanical ventilation. In conclusion, both repeat PDT and awake PDT, both separately or together, can be very useful in the management of critical care and pre-critical care patients and merit wider use. 相似文献
696.
The use of cognitive task analysis to improve the learning of percutaneous tracheostomy placement 总被引:1,自引:0,他引:1
Sullivan ME Brown CV Peyre SE Salim A Martin M Towfigh S Grunwald T 《American journal of surgery》2007,193(1):96-99
OBJECTIVE: The purpose of the current study was to determine the effectiveness of using cognitive task analysis (CTA) to develop a curriculum to teach the behavioral skills and the cognitive strategies of a percutaneous tracheostomy (PT) placement. METHODS: Postgraduate 2, 3, and 4 general surgery residents were randomly assigned to either the CTA group (N = 9) or the control group (N = 11). The CTA group was taught percutaneous tracheostomy placement using the CTA curriculum. The control group received the traditional curriculum. RESULTS: The CTA group performed significantly higher on the PT procedure at 1 month (CTA: 43.5 +/- 3.7, control 35.2 +/- 3.9, P = .001) and at 6 months post-instruction (CTA: 39.4 +/- 4.2, control: 31.8 +/- 5.8, P = .004). In addition, the CTA group demonstrated superior cognitive strategies than the control group (CTA: 25.4 +/- 5.3, control: 19.2 +/- 2.0, P = .004). CONCLUSIONS: The use of CTA was effective in improving the cognitive processes and technical skills of performing a PT for surgical residents. 相似文献
697.
Shimohata T Ozawa T Nakayama H Tomita M Shinoda H Nishizawa M 《Journal of neurology》2008,255(10):1483-1485
Sudden death has been reported in patients with multiple system atrophy (MSA), although the frequency of this event has not
been well delineated. We investigated the frequency and potential causes of sudden death in patients with MSA. During the
5-year observation period, 10 of 45 patients with probable MSA died. The causes of death included sudden death of unknown
etiology (seven patients), aspiration pneumonia (one patient), asphyxia after vomiting (one patient), and lung cancer (one
patient). The mean survival time of patients with sudden death was 63.0 ± 24.7 months (range, 39–116 months). Among seven
patients who experienced sudden death, six were found to have died during sleep. Among these patients, two had been treated
with tracheostomy and three with continuous positive airway pressure (CPAP) or noninvasive positive pressure ventilation (NPPV)
during sleep, suggesting that these treatments do not always prevent sudden death in patients with MSA. Nocturnal sudden death
should be recognized as the most common mechanism of death in patients with MSA. 相似文献
698.
Tracheoarterial fistula (TAF) involves erosion through the tracheal wall into the innominate artery resulting in bleeding. It is a rare but lethal complication of tracheostomy. Mortality is 100% without operative interference. Even with appropriate management, a survival rate of only 14.3% has been reported. We report a case of TAF in a child, where rapid institution of resuscitative and operative measures resulted in survival. Initial temporary control of bleeding was achieved by hyperinflation of cuff. Computed tomography (CT) angiography confirmed the diagnosis. The damaged segment of the eroded artery was resected and ligated. This case highlights the role of early diagnosis and prompt aggressive therapy for management of this potentially lethal complication. 相似文献
699.
《Seminars in perinatology》2017,41(2):124-127
Neonates with chronic respiratory failure have uncertain prognosis and can face significant treatment burden. As the trajectory of the illness becomes more concerning, consultation with a pediatric palliative service should be considered, especially as therapeutic options shift from standard to “innovative.” Benefits include as follows: supporting emotionally conflicted providers and parents, maintaining transparency in determination of goals, and balancing medical progress with each individual patient’s and family’s best interests. 相似文献
700.
Prediction of prolonged mechanical ventilation in patients in the intensive care unit A cohort study
Alvaro Sanabria Ximena Gómez Valentín Vega Luis Carlos Domínguez Camilo Osorio 《Colombia Médica》2013,44(3):184-188