全文获取类型
收费全文 | 52492篇 |
免费 | 2854篇 |
国内免费 | 1637篇 |
专业分类
耳鼻咽喉 | 1212篇 |
儿科学 | 1211篇 |
妇产科学 | 705篇 |
基础医学 | 3060篇 |
口腔科学 | 1300篇 |
临床医学 | 6612篇 |
内科学 | 9156篇 |
皮肤病学 | 302篇 |
神经病学 | 1392篇 |
特种医学 | 2296篇 |
外国民族医学 | 20篇 |
外科学 | 14995篇 |
综合类 | 7074篇 |
现状与发展 | 2篇 |
预防医学 | 1671篇 |
眼科学 | 695篇 |
药学 | 2599篇 |
57篇 | |
中国医学 | 594篇 |
肿瘤学 | 2030篇 |
出版年
2024年 | 92篇 |
2023年 | 927篇 |
2022年 | 1644篇 |
2021年 | 2103篇 |
2020年 | 1993篇 |
2019年 | 1984篇 |
2018年 | 2000篇 |
2017年 | 1660篇 |
2016年 | 1673篇 |
2015年 | 1730篇 |
2014年 | 3612篇 |
2013年 | 3256篇 |
2012年 | 2803篇 |
2011年 | 3422篇 |
2010年 | 2968篇 |
2009年 | 2941篇 |
2008年 | 2808篇 |
2007年 | 2761篇 |
2006年 | 2486篇 |
2005年 | 2173篇 |
2004年 | 1696篇 |
2003年 | 1448篇 |
2002年 | 1295篇 |
2001年 | 957篇 |
2000年 | 737篇 |
1999年 | 600篇 |
1998年 | 491篇 |
1997年 | 479篇 |
1996年 | 423篇 |
1995年 | 384篇 |
1994年 | 323篇 |
1993年 | 274篇 |
1992年 | 246篇 |
1991年 | 215篇 |
1990年 | 174篇 |
1989年 | 160篇 |
1988年 | 188篇 |
1987年 | 152篇 |
1986年 | 124篇 |
1985年 | 188篇 |
1984年 | 215篇 |
1983年 | 130篇 |
1982年 | 154篇 |
1981年 | 136篇 |
1980年 | 130篇 |
1979年 | 99篇 |
1978年 | 71篇 |
1977年 | 90篇 |
1976年 | 92篇 |
1975年 | 73篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
32.
Joseph Wheatley Zhengyang Liu Joel Loth Mark P. Plummer Jahan C. Penny-Dimri Reny Segal Julian Smith Luke A. Perry 《Acta anaesthesiologica Scandinavica》2023,67(2):131-141
Background
Patients undergoing cardiac surgery are at significant risk of developing postoperative acute kidney injury (AKI). Neutrophil–lymphocyte ratio (NLR) is a widely available inflammatory biomarker which may be of prognostic value in this setting.Methods
We conducted a systematic review and meta-analysis of studies reporting associations between perioperative NLR with postoperative AKI. We searched Medline, Embase and the Cochrane Library, without language restriction, from inception to May 2022 for relevant studies. We meta-analysed the reported odds ratios (ORs) with 95% confidence intervals (CIs) for both elevated preoperative and postoperative NLR with risk of postoperative AKI and need for renal replacement therapy (RRT). We conducted a meta-regression to explore inter-study statistical heterogeneity.Results
Twelve studies involving 10,724 participants undergoing cardiac surgery were included, with eight studies being deemed at high risk of bias using PROBAST modelling. We found statistically significant associations between elevated preoperative NLR and postoperative AKI (OR 1.45, 95% CI 1.18–1.77), as well as postoperative need for RRT (OR 2.37, 95% CI 1.50–3.72). Postoperative NLR measurements were not of prognostic significance.Conclusions
Elevated preoperative NLR is a reliable inflammatory biomarker for predicting AKI following cardiac surgery. 相似文献33.
PurposeType B aortic dissection is a rare but life-threatening disease. Thoracic endovascular aortic repair (TEVAR) was widely used for Type B aortic dissection patients in the last decade due to the lower mortality and morbidity compared with open chest surgical repair (OCSR). AKI in type B aortic dissection is a well-recognized complication and indicates poor short-term and long-term outcome. The objective of this concise review was to identify the risk factors and the impact of AKI on type B aortic dissection patients.Methods and resultsA literature search was performed using PubMed, Embase, MEDLINE, and Cochrane Library with the search terms ‘type B aortic dissection’ and ‘acute kidney injury’ (AKI), and all English-language literatures published in print or available online from inception through August 2020 were thoroughly reviewed. Studies that reported relative AKI risks and outcomes in type B aortic dissection patient were included. Major mechanisms of AKI in type B aortic dissection included renal hypoperfusion, inflammation response, and the use of contrast medium. Type B aortic dissection patients with AKI significantly had increased hospital stay duration, need of renal replacement therapy, and 30-d and 1-year mortality.ConclusionsAKI in type B aortic dissection is a well-recognized complication and associated with poor short-term and long-term outcome. Early identification of high-risk patients, early diagnosis of AKI, stabilization of the hemodynamic parameters, avoidance of nephrotoxic drugs, and optimization of the use of contrast agents are the major strategies for the reduction of AKI in type B aortic dissection patients. 相似文献
34.
35.
Walid K. Abu Saleh Phillip Mason Odeaa Al Jabbari Hany Samir Brian A. Bruckner 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》2015,42(6):569-571
The Impella 5.0, a percutaneously inserted left ventricular assist device, has been used to support patients who have severe heart failure or who are undergoing high-risk percutaneous coronary intervention. We report our surgical placement of the Impella 5.0, through a graft sewn to the aorta, to unload the left ventricle of a 59-year-old man who was undergoing venoarterial extracorporeal membrane oxygenation for postcardiotomy shock. The patient underwent successful placement of a long-term left ventricular assist device before his discharge from the hospital. The versatility of the Impella 5.0 is exemplified in this patient who was successfully bridged to long-term support. 相似文献
36.
37.
室管膜瘤是一种原发于神经上皮的中枢神经系统肿瘤,病变累及脑和脊髓,多发于儿童。基因分型的新分类方法,为室管膜瘤的治疗和预后评估提供了更为可靠的依据。室管膜瘤对辅助治疗的敏感性低是造成患儿预后较差的重要原因之一。该文对近年来儿童室管膜瘤的分型、诊断、治疗策略等进行综述。 相似文献
38.
39.
《Journal of vascular and interventional radiology : JVIR》2020,31(1):150-154.e2
Thoracic endovascular aortic repair (TEVAR) for aneurysmal chronic dissection is often complicated by retrograde filling of the false lumen and dissected distal landing zone. A “cheese wire”-style fenestration of the dissection intimal flap can create a landing zone facilitating TEVAR. This technique successfully aided TEVAR in 3 patients with an average age of 57.3 years. Complications included type III endoleak requiring relining and renal artery occlusion requiring stent placement. Average duration of clinical follow-up was 19 ± 4 months. Imaging follow-up was 8 ± 10 months. All patients have survived for more than 1 year without aneurysm enlargement. 相似文献
40.