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61.
62.
报告手术治疗腰椎间盘突出症合并退行性腰椎管狭窄症104例。术后随访90例,随诊时6个月~6年。优良率86.5%,无腰椎不稳和腰椎滑脱等并发症。为获得优良效果,作者强调在处理椎间盘突出的同时必须彻底解除侧隐窝及神经根管,黄韧带肥厚对神经根的压迫,才能彻底根除症状 相似文献
63.
Raj P. Kapur Ian Neilson Robert M.W. Hofstra Lynda W. Holloway Ron C. Michaelis Kathleen A. Leppig 《American journal of medical genetics. Part A》2002,108(1):51-56
Congenital hydrocephalus associated with aqueductal stenosis and/or agenesis of the corpus callosum has been described in newborn males with mutations in L1CAM, a gene that encodes a neural cell adhesion molecule. These males usually have severe mental retardation and may have spastic paraplegia and adducted thumbs. In contrast, Hirschsprung disease, or absence of ganglion cells in the distal gut, has rarely been described in such individuals. We report a male infant who had severe hydrocephalus identified in the prenatal period with evidence of aqueductal stenosis and adducted thumbs at birth. He developed chronic constipation, and rectal biopsy confirmed the diagnosis of Hirschsprung disease. Molecular testing of the L1CAM gene revealed a G2254A mutation, resulting in a V752M amino acid substitution. A common polymorphism in RET, but no mutation, was identified. Our patient represents the third example of coincident hydrocephalus and Hirschsprung disease in an individual with an identified L1CAM mutation. We hypothesize that L1CAM‐mediated cell adhesion may be important for the ability of ganglion cell precursors to populate the gut, and that L1CAM may modify the effects of a Hirschsprung disease–associated gene to cause intestinal aganglionosis. © 2002 Wiley‐Liss, Inc. 相似文献
64.
赵诚 《中国介入影像与治疗学》2006,3(4):288-290
目的探讨代谢综合征(MS)患者中肾动脉狭窄的发生率及无创性筛检的必要性与可靠性。方法45例MS患者预行肾动脉螺旋CT血管造影(SCTA),对所检出的14例肾动脉狭窄者行肾动脉数字减影血管造影(DSA)对照,并对SCTA及DSA结果进行对比分析。结果45例MS患者中SCTA显示肾动脉正常31例,其余14例患者存在单侧或双侧肾动脉狭窄,DSA对照显示肾动脉正常6条,肾动脉狭窄22条,与SCTA显示的情况基本符合。结论MS患者中肾动脉狭窄的发生率约31.1%,对可疑患者应常规予以肾动脉SCTA检查。 相似文献
65.
腰椎管狭窄症的手术减压与内固定选择(259例临床分析) 总被引:20,自引:2,他引:18
目的:探讨腰椎管狭窄症的手术减压指征、减压范围及内固定选择。方法:回顾性分析腰椎管狭窄症患者259例,平均年龄52.2岁,平均病程4年1个月。根据病情分别采用椎板间节段开窗潜行减压术139例,腰椎管内径扩大成形术63例,全椎板切除减压、椎间植骨融合内固定术57例。结果:221例获得平均4年2个月随访。三种手术方法优良率分别为91.53%、87.50%和85.45%;手术并发症发生率为13.69%、15.87%和20.11%。结论:对严重的腰椎管狭窄症若手术适应证和减压范围掌握恰当,不论采取何种手术方式的神经减压术,均可取得满意疗效。正确选择病例和熟练的外科技术是应用内固定器械的重要条件。 相似文献
66.
67.
Twenty-two percutaneous transluminal balloon valvuloplasty procedures were performed on 21 patients with congenital pulmonary valve stenosis. The peak systolic pressure gradient was immediately reduced from 79.1 +/- 7.4 to 22.2 +/- 1.8 mmHg, (P less than 0.0001) and follow-up cardiac catheterization at 5.3 +/- 0.4 months in 19 patients revealed no further significant change in gradient (23.5 +/- 3.2 mmHg). The best results were obtained when balloons larger than the pulmonary annulus were used, i.e. an immediate residual transvalvular gradient of 22.0 +/- 2.2 mmHg with a balloon/annulus ratio greater than 1, as opposed to 44.2 +/- 5.4 with a balloon/annulus ratio = 1 (P less than 0.001). The angiographically determined cusp thickness of the stenotic pulmonary valves was significantly greater than that of the control group of 24 patients without pulmonary valve stenosis (1.21 +/- 0.09 vs 0.59 +/- 0.02 mmHg, P less than 0.00001). The relationship between this parameter and the residual transvalvular gradient at follow-up was found to be significant (r = 0.77, P less than 0.001). It is concluded that balloon size is a determinant factor in achieving good results with percutaneous balloon valvuloplasty although cusp thickness, a factor to which scant regard has hitherto been paid, also plays a significant role in the residual transvalvular gradient measured at follow-up. 相似文献
68.
高分辨MRI对颈动脉粥样硬化斑块成分显示的病理对照研究 总被引:3,自引:0,他引:3
目的分析和评价高分辨MRI对颈动脉粥样硬化斑块不同成分的显示效果,为颈动脉内膜切除术术前判断斑块稳定性提供参考。方法对26例行颈动脉内膜切除术的颈动脉粥样硬化性狭窄患者术前高分辨MRI 4种不同序列的影像(T1WI、T2WI、PDWI和3D TOF)与斑块标本病理进行逐层对照,分析斑块内不同成分的MRI影像特点。结果获得斑块28块,切为238段,主要分布于颈总动脉和颈内动脉,以复杂斑块为特征的Ⅳ~Ⅴ型58段(24.37%)和Ⅵ型79段(33.19%)为主;斑块内纤维帽主要表现为TOF序列的带状低信号,钙化和纤维化组织分别表现为在各序列影像上的不规则低信号和不特定信号,脂质池和坏死核呈T1WI、PDWI和3D TOF序列的等至稍高信号,近期出血表现为T1WI、T2WI和PDWI序列的明显高信号。结论高分辨MRI不仅可以清晰显示动脉粥样硬化斑块,进行动脉管腔狭窄程度的测定,通过多序列影像联合分析还可以分辨斑块内部不同成分,有助于术前对斑块稳定性的判断。 相似文献
69.
动脉自旋标记法磁共振成像在颈动脉狭窄性脑缺血疾病中的初步应用 总被引:2,自引:0,他引:2
目的:对比研究颈动脉严重狭窄患者动脉自旋标记法(ASL)和动态磁化率效应对比剂增强(DSC)磁共振脑灌注成像表现,探讨ASL的临床运用价值。材料和方法:健康自愿者12例,行DSC和ASL,计算左侧大脑中动脉供血区与右侧相应区域相对脑血流量(rCBF)比值并进行比较。病例组为单侧颈内动脉狭窄程度≥70%患者32例,计算DSC和ASL所得的患侧与健侧大脑中动脉供血区rCBF比值并进行比较。结果:12例健康自愿者所测的DSC和ASL的rCBF比值分别为1.0012±0.1030和1.0015±0.1611,无统计学差异。32例患者中,15例患者灌注异常,DSC与ASL的rCBF比值相比无显著性差异(P=0.072)。结论:ASL序列能快速无创的提供脑灌注情况,可作为初步了解颈动脉狭窄性脑缺血疾病脑灌注情况的常规检查方法。 相似文献
70.
Martin A. Luchtefeld M.D. Dr. Jeffrey W. Milsom M.D. Anthony Senagore M.D. James A. Surrell M.D. W. Patrick Mazier M.D. 《Diseases of the colon and rectum》1989,32(9):733-736
Anastomotic stenosis is a poorly understood and underexamined complication of gastrointestinal surgery, reportedly most frequent
in the coloproctostomy. In order to better define this problem, a questionnaire was sent to members of the American Society
of Colon and Rectal Surgeons regarding patients with gastrointestinal anastomotic stenosis. A total of 123 patients with intestinal
anastomotic stenosis were analyzed. Eighty-two anastomoses were stapled and 41 were handsewn. Nearly all stenoses occurred
in the distal bowel (70 rectal, 23 sigmoid colon). Preoperative risk factors identified were obesity (28 patients) and abscess
(12 patients). Incomplete “doughnuts” were noted in 12 patients. Postoperative anastomotic leaks (15 patients), pelvic infection
(13 patients), and postoperative radiation (7 patients) were believed to be contributing factors. Dilatation, using a variety
of techniques, was the sole treatment for 65 patients, however, intra-abdominal surgery was necessary in 34 patients. Large
intestinal anastomotic stenosis probably occurs most commonly following coloproctostomy (both with handsewn and stapled anastomoses).
Dilatation alone resulted in adequate treatment in most patients in the study. Major surgery was required to correct this
problem in a significant number of patients (28 percent) in this series. The true incidence of anastomotic stenosis in colorectal
surgery is unknown and warrants further study.
Poster presentation at the meeting of the American Society of Colon and Rectal Surgeons, Anaheim, California, June 12 to 17,
1988. 相似文献