首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   19129篇
  免费   1327篇
  国内免费   521篇
耳鼻咽喉   573篇
儿科学   209篇
妇产科学   144篇
基础医学   1586篇
口腔科学   685篇
临床医学   1749篇
内科学   1271篇
皮肤病学   44篇
神经病学   2308篇
特种医学   803篇
外科学   5668篇
综合类   2258篇
预防医学   731篇
眼科学   1356篇
药学   849篇
  10篇
中国医学   319篇
肿瘤学   414篇
  2024年   70篇
  2023年   400篇
  2022年   809篇
  2021年   956篇
  2020年   942篇
  2019年   771篇
  2018年   796篇
  2017年   885篇
  2016年   806篇
  2015年   776篇
  2014年   1413篇
  2013年   1475篇
  2012年   1039篇
  2011年   1162篇
  2010年   968篇
  2009年   972篇
  2008年   858篇
  2007年   899篇
  2006年   734篇
  2005年   622篇
  2004年   553篇
  2003年   431篇
  2002年   346篇
  2001年   285篇
  2000年   196篇
  1999年   210篇
  1998年   193篇
  1997年   155篇
  1996年   144篇
  1995年   114篇
  1994年   90篇
  1993年   79篇
  1992年   73篇
  1991年   60篇
  1990年   51篇
  1989年   61篇
  1988年   48篇
  1987年   37篇
  1986年   39篇
  1985年   68篇
  1984年   78篇
  1983年   76篇
  1982年   60篇
  1981年   56篇
  1980年   31篇
  1979年   29篇
  1978年   33篇
  1977年   8篇
  1976年   12篇
  1975年   5篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
151.
Dermato-fibro-sarcomas are known for high-recurrence rates. The gold standard of management is surgical excision with clear margins. Such margins on the chest results in large defects which require complex reconstructive procedures. We report a case series of patients managed by a multidisciplinary team with good outcomes. A total of 12 patients with extensive dermato-fibro-sarcoma of the anterior chest wall were treated over a period of 5 years in our setting. The age range was 25 to 54 years. Skeletal defects were reconstructed with Prolene mesh and methyl acrylate cement in 10 of the 12 patients. Pedicle flaps were used in nine patients. All margins were clear of tumors, with the nearest margin being 1.5 cm. One patient had a recurrence. No donor-site morbidity was recorded in any of the patients.In conclusion, a multidisciplinary approach provides improved outcomes in the management of large dermato-fibro-sarcomas of the chest wall. With this approach, extensive dissection of the tumor is achieved, and reconstruction is performed with minimal complication.  相似文献   
152.
The choice of the most suitable surgical approach to the elbow forms the foundation of any successful elbow surgery. The surgical approach is based on the injury or pathology to be addressed and therefore specific anatomical details need to be considered. The surgeon must be comfortable with the bony, ligamentous and neurovascular anatomy of the elbow to consider and execute the best approach for each problem. This is an imperative to avoid iatrogenic injury.This article provides a detailed analysis, valuable technical tips, advantages and disadvantages of the most common approaches to the elbow. The lateral approaches include the Kocher, Kaplan and Extensor Digitorum Communis (EDC) Split approaches, the medial approaches include the Hotchkiss, Flexor carpi ulnaris (FCU) splitting approach, the Taylor and Scham approach. The anterior approach includes the anterior neurovascular interval approach and the posterior approaches include the Olecranon osteotomy, triceps sparing, triceps reflecting approach and finally the Boyd interval approach. The text and illustrations will provide a structured overview for the practicing surgeon.  相似文献   
153.
目的 解剖观察完全神经内镜下经Poppen锁孔入路开颅松果体区手术的相关解剖结构及其特征,并探讨该术式的可行性。方法 选取12具经10%甲醛固定、红蓝乳胶灌注的成人尸头湿标本进行实验观察,其中男7例、女5例,年龄34~71岁。应用随机数字表法将12具标本随机分为内镜组和显微组,每组6具,分别采用完全神经内镜Poppen锁孔入路和显微镜常规Poppen入路进行模拟开颅手术松果体区手术。模拟手术中,利用神经导航对松果体区以及手术间隙进行观察测量:(1)观察2组松果体区重要解剖结构;(2)内镜组术中,于剪开小脑幕前后,分别测量松果体区暴露面积,并采用配对t检验进行比较;(3)内镜组与显微镜组术中,分别测量第1、2、3手术间隙的暴露面积,并采用独立样本t检验进行组间比较;(4)其他重要解剖结构间距的神经内镜测量。结果 (1)2种入路均可观察到双侧基底静脉、小脑中脑裂静脉、大脑内静脉、大脑后动脉、小脑上动脉等重要血管,以及滑车神经、四叠体、胼胝体压部和松果体等重要解剖结构,但显微镜常规Poppen入路的手术通道狭窄、倾斜,视野局限。(2)内镜组模拟手术中,剪开小脑幕前后松果体区显露面积分别为(73.14±3.38)mm2和(127.77±7.90)mm2,剪开后明显大于剪开前,差异有统计学意义(t=28.84,P<0.001)。(3)内镜组和显微镜组模拟手术中,第1、2、3手术间隙的暴露面积分别为(20.93±2.49)mm2、(72.55±4.18)mm2、(208.57±11.79)mm2和(9.12±1.12)mm2、(53.45±3.17)mm2、(175.29±9.98)mm2,内镜组均大于显微镜组,差异均有统计学意义(t=14.92、12.61、7.41,P值均<0.001)。(4)神经内镜测量显示:双侧基底静脉最大距离为(14.41±0.94)mm,双侧小脑中脑裂静脉最大距离为(8.23±0.84)mm,双侧大脑内静脉最大距离为(8.41±0.96)mm,双侧大脑内静脉最小距离(第1间隙最窄长度)为(2.58±0.22)mm,松果体中心点至丘脑枕部中心点距离为(16.83±1.16)mm。结论 完全神经内镜下经Poppen锁孔入路模拟手术中间隙恒定,可安全到达松果体区;与显微镜常规Poppen入路相比,完全神经内镜Poppen锁孔入路的手术操作空间更大,松果体区显露得更充分。  相似文献   
154.
目的:探讨经结肠系膜入路腹腔镜离断性肾盂成形术治疗小儿肾盂输尿管连接部梗阻的临床效果。方法:回顾分析2014年1月至2018年4月为96例左侧肾盂输尿管连接部梗阻患儿行腹腔镜离断性肾盂成形术的临床资料,其中经腹腔结肠系膜途径46例(观察组),经腹膜后途径50例(对照组),对比分析两组手术时间、术中出血量、引流管留置时间、术后进食时间、术后住院时间、并发症、肾脏恢复情况等。结果:手术均一次性完成。观察组与对照组手术时间[75(70,90)min vs.100(83,106)min]差异有统计学意义(P<0.001);两组术中出血量、引流管留置时间、术后进食时间、术后住院时间差异无统计学意义(P>0.05)。对照组术后1例出现漏尿,引流管术后9 d拔除,导致术后住院时间延长至11 d,余者均无并发症发生。术后随访24个月,两组肾积水、分肾功能恢复方面差异无统计学意义(P>0.05)。结论:经结肠系膜入路腹腔镜离断性肾盂成形术治疗小儿肾盂输尿管连接部梗阻具有操作空间大、手术时间短、不增加肠道干扰的优点,值得推广。  相似文献   
155.
Pillar pain represents one of the most common complications of classic open carpal tunnel release (CTR). This complication causes a sense of discomfort worse than the compression syndrome itself. We, herein, introduce a new treatment method for CTR through a mini-incision, which allows subcutaneously cutting the transverse carpal ligament (TCL) and releasing the median nerve without neurovascular complications. This mini-incision approach can allow the direct visualization and preservation of the thenar motor branch in those rare cases where it has an aberrant origin. For the past 10 years, we have consecutively performed this technique in the surgical treatment of 318 patients with the diagnosis of primary CTS, without developing any neurovascular and tendon injuries as well as pillar pain.  相似文献   
156.
157.
Study Design: Systematic review and meta-analysis.Objective: To compare the effectiveness and safety between anterior and posterior approach, and determine the best surgical methods for the treatment of ossification of the posterior longitudinal ligament (OPLL) in the cervical spine.Methods: We searched the Cochrane Library, PubMed, CNKI and Wanfang Med Data databases from January 2007 to March 2018. Japanese Orthopaedic Association (JOA) scores, cervical lordosis, functional recovery rates, excellent and good outcomes of the surgical approaches, and complication and reoperation rates were analyzed. RevMan 5.3 was utilized for data analysis.Results: Eleven studies were included in the meta-analysis. By comparing the anterior and posterior approaches for the treatment of OPLL in the cervical spine, statistically significant differences were found in the preoperative initial JOA, the postoperative final JOA scores, functional recovery rates, complication rates, excellent and good outcomes of the surgical approaches and reoperation rates. However, no statistically significant difference in the occurrence of the preoperative and postoperative cervical lordosis was noted.Conclusion: The anterior approach is superior to the posterior approach in terms of the postoperative final JOA score, functional recovery rate, and clinical outcomes. Although the complication and reoperation rates of the anterior approach are higher than those of the posterior approach. We recommend the anterior approach for the treatment of OPLL when patients with occupying ratio ≥ 60%. In addition, high-quality studies with long-term follow-up and large sample size are also needed.  相似文献   
158.
159.
BackgroundIn severe cases of ankle and subtalar arthritis, arthrodesis of the subtalar joint is performed in combination with ankle arthroplasty. In these special cases gait analysis reveals real motion at the replaced tibiotalar joint.MethodsTwenty-three patients affected by ankle and subtalar arthritis, treated either with a 3-component or a 2-component prosthesis in combination with subtalar arthrodesis, were clinically evaluated preoperatively and at a minimum of 1-year follow-up. Gait analysis was performed postoperatively using a multi-segment foot protocol. Foot kinematics were compared to corresponding data from a healthy control group.ResultsClinical scores significantly improved from preoperative to follow-up. The clinically measured passive ankle dorsiflexion/plantarflexion significantly improved at the follow-up. Patients’ normalized walking speed and stride length were significantly lower than those in control. With exception of the ankle frontal-plane motion, sagittal-plane mobility of foot joints was about 50% than that in healthy joints.ConclusionsImprovement in clinical scores was found for both prostheses. Normal spatio-temporal parameters were not restored. In these patients, fusion of the subtalar joint appeared to be compensated by larger frontal-plane motion at the tibiotalar joint.Level of evidenceLevel III- retrospective comparative study.The study was approved by the local Ethics Committee as protocol MAT (protocol registration at clinicaltrials.gov NCT03356951).  相似文献   
160.
BackgroundOur aim in this study was to identify the fibular footprint of the Anterior Inferior Tibiofibular Ligament (AITFL) and its relation to Wagstaffe fracture fragment size.MethodsWe examined 25 cadaveric lower limbs which were carefully dissected to identify the lateral ankle ligaments. The AITFL anatomy was compared to 40 Wagstaffe fractures identified from our ankle fracture database.ResultsThe AITFL origin was from the anterior fibular tubercle with an average length of 21.61 mm (95% CI 20.22, 22.99). The average distance of the distal aspect of the AITFL footprint to the distal fibula margin was 11.60 mm (95% CI 10.49, 12.71). In the ankle fractures analyzed, the average length of the Wagstaffe fragment was 17.88 mm (95% CI 16.21, 19.54). The average distance from the distal tip of the fibula to the Wagstaffe fracture fragment was 21.40 mm (95% CI 19.78, 23.01).In total there were 22 syndesmosis injuries. There was no statistical difference in Wagstaffe fragment size between stable and unstable groups.ConclusionThe AITFL fibular origin was both larger and more distal than the Wagstaffe fracture fragments seen in our institution. Therefore, this suggests that a ligamentous failure will also have to occur to result in syndesmotic instability. The size of fracture fragment also did not confer to syndesmotic instability on testing.Level of Evidence - 3  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号