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71.
目的 建立一测多评(quantitative analysis of multicomponents by single-marker,QAMS)法同时检测盐沙苑子饮片中杨梅素、扁蓄苷、杨梅素-3-O-β-D-葡萄糖苷、毛蕊异黄酮葡萄糖苷、西伯利亚落叶松黄酮、沙苑子苷B、沙苑子苷A、毛蕊异黄酮、芒柄花素、鼠李柠檬素、豆甾醇、胡萝卜苷、β-谷甾醇含量的方法,并采用主成分分析法(principal component analysis,PCA)、正交偏最小二乘法-判别分析(orthogonal partial least squares-discriminant analysis,OPLS-DA)法及熵权逼近理想解排序(entropy weight-technique for order preference by similarity to ideal solution,EW-TOPSIS)法对其质量进行评价。方法 采用Lichrospher C18色谱柱;乙腈-0.2%磷酸水溶液为流动相梯度洗脱。以沙苑子苷A为内参物,建立内参物与其他12个待测成分的相对校正因子(relative co... 相似文献
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Jo-Lynn S. Tan Niranjan Sathianathen Marcus Cumberbatch Prokar Dasgupta Alexandre Mottrie Ronney Abaza Koon Ho Rha Thyavihally B. Yuvaraja Dipen J. Parekh Umberto Capitanio Rajesh Ahlawat Sudhir Rawal Nicolò M. Buffi Ananthakrishnan Sivaraman Kris K. Maes Gagan Gautam Francesco Porpiglia Levent Turkeri Mahendra Bhandari Benjamin Challacombe James Roscoe Porter Craig R. Rogers Daniel A. Moon 《BJU international》2021,128(Z3):30-35
75.
Daniela A. Haehn Essa M. Bajalia Katherine J. Cockerill Amanda E. Kahn Colleen T. Ball David D. Thiel 《Translational andrology and urology》2021,10(1):227
BackgroundAdherent perinephric fat (APF) contributes to surgical complexity and can be associated with adverse perioperative outcomes for partial nephrectomy (PN). The Mayo Adhesive Probability (MAP) score accurately predicts the presence of APF during robotic-assisted partial nephrectomy (RAPN). Our primary aim is to validate MAP score as a predictor of APF in open partial nephrectomy (OPNx).MethodsWe reviewed 105 consecutive OPNx (100 patients) performed by a single surgeon with intraoperative determination of APF. We evaluated the ability of the MAP score to discriminate between those with APF and those without APF by estimating the area under the receiver operating characteristic curve (AUROCC). The association of perioperative outcomes with APF was evaluated as well.ResultsForty-three patients [49%; 95% confidence interval (CI), 39–59%] had intraoperative identification of APF. The MAP score had excellent ability to predict APF in OPNx (AUROCC, 0.82; 95% CI, 0.74–0.92). APF was observed in 6% of patients with a MAP score of 0-1, 27% with score 2, 52% with score 3, 75% with score 4, and 90% with score 5. The presence of APF was associated with longer operative times (P=0.004) and higher estimated blood loss (EBL) (P=0.003). Although not statistically significant, our study did suggest that APF may be associated with postoperative complications and prolonged length of stay (LOS) (>3 days).ConclusionsMAP score accurately predicts the presence of APF in patients undergoing OPNx. APF is associated with longer operative time and higher blood loss in OPNx. 相似文献
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Jian Qian Qian Zhang Qiang Cao Jie Jiang Pu Li Meiling Bao Chao Qin Zengjun Wang Lixin Hua Pengfei Shao 《Translational andrology and urology》2021,10(3):1030
BackgroundThis study investigated a comfortable suture angle (CSA) with optimized trocar position for closing the defect during renorrhaphy in retroperitoneal laparoscopic partial nephrectomy (LPN). The feasibility, usefulness, and safety of achieving the CSA with modified trocar position were determined for different tumor types.MethodsTwo optimized trocar positions were introduced for different tumor types. A suture angle was based on the tumor plane of the superficial parenchyma defect and the line formed by the needle holder. Preliminary surgical simulations determined a CSA that combined the least suture time with the greatest ease of performance. Achieving the CSA was attempted during renorrhaphy of 106 enrolled patients undergoing retroperitoneal LPN. Patients’ characteristics, operative features, and follow-up information were collected and analyzed.ResultsFor 89 (83.96%) patients, a CSA was successfully reached and parenchyma recovered. The remaining 17 patients were successfully sutured, but the attempt to achieve a CSA failed. For the CSA group, the suture, clamping, and overall operative times were significantly less than that of the non-CSA patients. The groups were similar regarding estimated blood loss, positive surgical margin, and rates of glomerular filtration reduction and complications. Univariable analyses determined that tumor location, growth pattern, and R.E.N.A.L. nephrometry score (RNS) may influence the success of this approach. Multivariable analyses indicated that only tumor location and RNS were independent factors affecting successful achievement of the CSA.ConclusionsThrough different kidney position changes, the CSA could be used to ease the suture process. It is feasible and safe to perform a CSA with optimized trocar position during LPN. Tumor location and RNS may influence the approach to get a CSA. 相似文献
77.
Three children are reported with typical cat eye syndrome (CES) and three more children with partial CES because of absence of coloboma, in which the supernumerary marker chromosome was studied by FISH. Using a genomic library, and also a centromeric and particularly a cosmid probe of 22q11, partial tetrasomy was shown in all cases. 相似文献
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本文讨论了常规设计的游离端义齿存在的问题,并对Kratochvil提出的RPI卡环,结合力学知识,提出了RPI卡环在游离端义齿应用中的优缺点,并通过典型病例介绍和对20名病例随访分析表明,用RPI卡环修复游离端牙齿缺失,可获得较好的临床效果。 相似文献
80.
胃粘膜内pH值测定在危重病人中的预警价值 总被引:3,自引:0,他引:3
目的 :观察在危重病患者中反映组织水平氧代谢的胃粘膜内 p Hi,与反映全身氧代谢的指标间的关系以及胃粘膜内p Hi的预警价值。方法 :用胃张力计测定危重病患者入科即刻及治疗 2 4h后胃粘膜内 p Hi,并测定 p Ha ,Pa O2 / Fi O2 ,行 APACHE 评分。结果 :死亡组入科即刻 p Hi( 7.13 3± 0 .3 74)较存活组 ( 7.3 89± 0 .0 62 )显著降低 ( P<0 .0 1) ,治疗 2 4小时后胃粘膜内 p Hi死亡组( 6.911± 0 .496)较存活组 ( 7.43 4± 0 .0 5 1)降低更显著 ( P<0 .0 0 1) ;入科即刻 p Hi≤ 7.3 2的患者病死率为 75 .0 %,治疗 2 4h后胃粘膜内 p Hi≤ 7.3 2的患者病死率为 88.9%。结论 :作为局部组织氧合指标的 p Hi在常规的全身氧代谢指标未改变之前就发生了明显的变化 ;p Hi的降低与病死率有明显的相关性。 相似文献