全文获取类型
收费全文 | 165888篇 |
免费 | 46894篇 |
国内免费 | 1881篇 |
专业分类
耳鼻咽喉 | 2199篇 |
儿科学 | 6354篇 |
妇产科学 | 2670篇 |
基础医学 | 30307篇 |
口腔科学 | 7723篇 |
临床医学 | 18460篇 |
内科学 | 31783篇 |
皮肤病学 | 5049篇 |
神经病学 | 21834篇 |
特种医学 | 7328篇 |
外国民族医学 | 7篇 |
外科学 | 19045篇 |
综合类 | 8610篇 |
现状与发展 | 3篇 |
一般理论 | 13篇 |
预防医学 | 12917篇 |
眼科学 | 2996篇 |
药学 | 16225篇 |
67篇 | |
中国医学 | 6322篇 |
肿瘤学 | 14751篇 |
出版年
2024年 | 149篇 |
2023年 | 851篇 |
2022年 | 1503篇 |
2021年 | 3570篇 |
2020年 | 7784篇 |
2019年 | 13009篇 |
2018年 | 12526篇 |
2017年 | 13755篇 |
2016年 | 12830篇 |
2015年 | 12684篇 |
2014年 | 13870篇 |
2013年 | 15052篇 |
2012年 | 13286篇 |
2011年 | 13573篇 |
2010年 | 11627篇 |
2009年 | 7854篇 |
2008年 | 8431篇 |
2007年 | 6830篇 |
2006年 | 6388篇 |
2005年 | 5978篇 |
2004年 | 5530篇 |
2003年 | 5189篇 |
2002年 | 4571篇 |
2001年 | 3716篇 |
2000年 | 2362篇 |
1999年 | 1219篇 |
1998年 | 878篇 |
1997年 | 875篇 |
1996年 | 809篇 |
1995年 | 783篇 |
1994年 | 658篇 |
1993年 | 555篇 |
1992年 | 515篇 |
1991年 | 466篇 |
1990年 | 475篇 |
1989年 | 402篇 |
1988年 | 292篇 |
1987年 | 256篇 |
1986年 | 318篇 |
1985年 | 435篇 |
1984年 | 417篇 |
1983年 | 255篇 |
1982年 | 332篇 |
1981年 | 268篇 |
1980年 | 289篇 |
1979年 | 212篇 |
1978年 | 176篇 |
1977年 | 166篇 |
1976年 | 154篇 |
1975年 | 111篇 |
排序方式: 共有10000条查询结果,搜索用时 718 毫秒
11.
12.
13.
Daniel Schar Pawin Padungtod Nguyen Tung Michael OLeary Wantanee Kalpravidh Filip Claes 《Influenza and other respiratory viruses》2019,13(6):618-621
Among the chief limitations in achieving early detection and control of animal‐origin influenza of pandemic potential in high‐risk livestock populations is the existing lag time between sample collection and diagnostic result. Advances in molecular diagnostics are permitting deployment of affordable, rapid, highly sensitive, and specific point‐of‐capture assays, providing opportunities for targeted surveillance driving containment strategies with potentially compelling returns on investment. Interrupting disease transmission at source holds promise of disrupting cycles of animal‐origin influenza incursion to endemicity and limiting impact on animal production, food security, and public health. Adoption of new point‐of‐capture diagnostics should be undertaken in the context of promoting robust veterinary services systems and parallel support for operationalizing pre‐authorized plans and communication strategies that will ensure that the full potential of these new platforms is realized. 相似文献
14.
15.
16.
17.
18.
Julie Despres Yasmina Ramdani Marine di Giovanni Magalie Bnard Abderrakib Zahid Mait Montero‐Hadjadje Florent Yvergnaux Thibaut Saguet Azeddine Driouich Marie‐Laure Follet‐Gueye 《Experimental dermatology》2019,28(8):922-932
It is well recognized that the world population is ageing rapidly. Therefore, it is important to understand ageing processes at the cellular and molecular levels to predict the onset of age‐related diseases and prevent them. Recent research has focused on the identification of ageing biomarkers, including those associated with the properties of the Golgi apparatus. In this context, Golgi‐mediated glycosylation of proteins has been well characterized. Additionally, other studies show that the secretion of many compounds, including pro‐inflammatory cytokines and extracellular matrix–degrading enzymes, is modified during ageing, resulting in physical and functional skin degradation. Since the Golgi apparatus is a central organelle of the secretory pathway, we investigated its structural organization in senescent primary human dermal fibroblasts using confocal and electron microscopy. In addition, we monitored the expression of Golgi‐related genes in the same cells. Our data showed a marked alteration in the Golgi morphology during replicative senescence. In contrast to its small and compact structure in non‐senescent cells, the Golgi apparatus exhibited a large and expanded morphology in senescent fibroblasts. Our data also demonstrated that the expression of many genes related to Golgi structural integrity and function was significantly modified in senescent cells, suggesting a relationship between Golgi apparatus function and ageing. 相似文献
19.
Jakub Pazdrowski Aleksandra Daczak‐Pazdrowska Adriana Polaska Joanna Ka
mierska Wojciech Barczak Mateusz Szewczyk Pawe Golusiski Zygmunt Adamski Ryszard aba Wojciech Golusiski 《Skin research and technology》2019,25(6):857-861
Radiodermatitis is one of the commonest side effects of radiotherapy. They are usually assessed by semi‐quantitative clinical scores, which are not validated and may be subject to inter‐observer variability. A few previous studies suggested that high‐frequency ultrasonography (HF‐USG) is useful in the assessment of the acute phase of radiation dermatitis in breast cancer patients. (a) To monitor skin changes by HF‐USG during the course of radiotherapy due to head and neck cancers, and (b) to determine whether there is any connection between skin sonograms and the skin scoring criteria. This prospective, observational study includes patients diagnosed with head and neck cancers, treated with radiotherapy or concomitant chemoradiation. The final analysis includes six patients. In every patient, the HF‐USG as well as dermatological assessment (target lesion score—TLS and CACE v. 4.0) were performed 4×: before, in the middle, day after, and 3 months after radiotherapy. There were significant differences between non‐irradiated skin thickness and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P < .0001), as well as between irradiated, unchanged skin thickness (TLS grade 0) and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P = .0002). There was no significant difference between non‐irradiated and irradiated, unchanged skin thickness (TLS grade 0; P = .9318). In four patients, we demonstrated subepidermal low echogenic band (SLEB). HF‐USG can be useful tool to noninvasive and objective assessment of skin changes during radiotherapy. 相似文献
20.
【目的】 探索建设世界一流科技期刊的策略,以助力中国科技期刊冲刺世界一流水平。【方法】 通过研读相关政策和研究文献,结合对Nature、Science、The Lancet、Cell等不同类型的世界一流科技期刊的分析,解析世界一流科技期刊的概念及内涵,探讨建设世界一流科技期刊的充分条件和必要条件,提出建设世界一流科技期刊的建议。【结果】 卓越的办刊理念、全方位的国际化水平、世界一流的人才队伍、先进的经营管理水平以及汇聚一流前沿成果、卓著的科学声望是建设世界一流科技期刊的必要条件。“高、精、尖”和“稳、准、狠”的办刊策略,是建设世界一流科技期刊的充分条件。建设世界一流科技期刊要理性且准确地认知其内涵,始终坚持卓越的办刊理念、国际化战略、人才战略、质量战略和集群化战略。【结论】 中国科技期刊既要扎根祖国大地,又要学习世界一流期刊的成功经验,从办刊的硬实力和软实力方面吸收借鉴,才能探索出具有中国特色的世界一流科技期刊建设路径。 相似文献