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排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
Enrico Verrina Barbara Andreetta Sergio Bassi Roberto Bonaudo Domenica A. Caringella Alfonso Castellani Pierluigi Cavalli Alberto Edefonti Giancarlo Lavoratti Luigi Longo Ivana Pela Rosa Penza Francesco Perfumo Virgilio Petrucci Marina Picca Mauro Ragaiolo Stefano Rinaldi Gianfranco Rizzoni Palma Sorino Giusto Viglino Graziella Zacchello Rosanna Gusmano 《Pediatric nephrology (Berlin, Germany)》1992,6(1):78-81
The results of the first 3 year' collaboration of the Italian Registry of Paediatric Chronic Peritoneal Dialysis (CPD) (1986–1988) are presented. This Registry acquired data on the majority of the paediatric patients treated with CPD in Italy, thus providing a national picture in a field where few nationwide surveys are available. Patients of less than 15 years of age at the start of dialysis were enrolled and clinical data collected until the age of 19 years. The number of nephrological paediatric centres participating in the Registry increased from 7 in 1986 to 11 in 1988. The total number of patients on CPD was 70 and the percentage of dialysed children treated with CPD ranged from 40.2% to 43.6%. Data on 89 peritoneal catheters were collected: during 1417 dialysis-months 70 catheter-related complications were observed (1:20.8 dialysis-months); actuarial catheter survival was 92.7% at 6 months, 84.8% at 1 year and 68.8% at 2 years. The incidence of peritonitis changed from 1 episode every 10.9 patient-months in 1986 to 1 every 19.8 in 1988. Abdominal hernias were the other main clinical complication observed. The survival of patients was 92.5% at 3 years, while the technique survival at the same time was 84%. 相似文献
72.
对HCV血清标记阳性的静脉内毒瘤者进行半年和15个月随访,并调查影响转归的部分因素。结果显示,静脉内毒瘾者抗-HCV自然转阴率分别为11.0/和33.3%。单因素和多因素分析均提示转阴率以婚姻状况良好的已婚者较离婚者高、人均年收入高者较低者高,说明婚姻状况和人们的经济水平对毒瘾者抗-HCV转阴有一定的影响。 相似文献
73.
74.
No evidence for association between the −112G/A polymorphism of UGRP1 and childhood atopic asthma 总被引:1,自引:0,他引:1
Z. Jian J. Nakayama E. Noguchi M. Shibasaki† T. Arinami 《Clinical and experimental allergy》2003,33(7):902-904
BACKGROUND: Susceptibility to asthma is known to involve genetic factors. Genome-wide screens have indicated that the chromosome 5q31-q34 region is linked to and/or associated with asthma. A new gene, named UGRP1 and reported by Niimi et al., encodes uteroglobin-related protein and is expressed in the lung and trachea. Niimi et al. showed the -112G/A polymorphism of the UGRP1 gene to be associated with asthma in a case-control study. OBJECTIVE: The objective of the present study was to replicate this association and confirm the possible role of the UGRP1-112G/A polymorphism in the aetiology of childhood asthma in a Japanese population. METHODS AND RESULTS: We conducted a transmission disequilibrium test (TDT) in 131 families identified through paediatric patients being treated for asthma. A case-control study was also carried out by comparing the probands and 137 unrelated non-atopic non-asthmatic Japanese children and 211 unrelated healthy Japanese adults. The -112G/A polymorphism was genotyped by the PCR-RFLP method. The TDT revealed that the -112A allele was not preferentially transmitted to asthma-affected children (P=0.85). Neither the presence of at least one A allele in an individual's genotype (sum of the G/A and A/A genotypes) nor the -112A allele was more prevalent among the asthma subjects than among the control subjects. CONCLUSION: Our findings indicate that the UGRP1-112G/A polymorphism does not play a substantial role in genetic predisposition to childhood asthma in this Japanese population. 相似文献
75.
以液体稀释法比较了自制与进口十六烷基吡啶作用于4种口腔常见微生物的最低抑菌浓度和最低杀菌浓度的实验结果,经t检验证明两者间无显著差异,提示自制氯化十六烷基吡啶的药效质量可靠。并就控制接种菌量及杀菌机理等问题作了初步探讨。 相似文献
76.
Dr. Shosaku Nakahara M.D. Hideaki Itoh M.D. Ryuichi Mibu M.D. Shinichi Ikeda M.D. Yoshihiro Oohata M.D. Kamesaburo Kitano M.D. Yoshihiko Nakamura M.D. 《Diseases of the colon and rectum》1988,31(10):762-766
Anorectal function was evaluated in eight patients who had low anterior resection of the rectum with a low anastomotic line,
using an EEA™ stapler, with determination of function based on periodic manometric studies and clinical symptoms. Immediately following
surgery all patients suffered from frequent bowel actions and soiling. These symptoms improved with time and most patients
could enjoy almost normal daily life by the sixth postoperative month. One month after surgery, anal canal resting pressure
and maximum squeeze pressure were significantly reduced and rectoanal inhibitory reflex was absent; neither showed a distinct
tendency to improve thereafter. Rectal sensation and reservoir capacity, which also were seriously impaired, recovered satisfactorily
by the time of the six-month examination. This suggests that an improvement of clinical symptoms following this operation
is dependent upon the recovery of reservoir capacity and sensation of the neorectum, and that this operative procedure is
a functionally acceptable option for low rectal cancer. 相似文献
77.
Ruprecht Nitschke Charles Pratt Michael Harris Jeffrey Krischer Teresa J. Vietti Holcombe Grier Willem Kamps Stuart Toledano 《Investigational new drugs》1992,10(2):93-96
CHIP (325 mg/M2), a second generation cisplatin derivative, was administered intravenously every 3 weeks to 85 pediatric patients with recurrent sarcomas (19), osteosarcomas (20), neuroblastoma (23), germ cell tumors (10), and other malignant tumors (7). Thirty-eight of them had been previously exposed to cisplatin. Partial remissions were only observed in 3 of 23 (13% SE=7%) patients having neuroblastoma. Severe thrombocytopenia (65%) and neutropenia (35%) were the dose limiting factors. 相似文献
78.
79.
B. H. Green J. R. M. Copeland M. E. Dewey V. Sharma I. A. Davidson 《International journal of geriatric psychiatry》1994,9(10):789-795
The Liverpool Continuing Health in the Community Study has followed up 1070 elderly community subjects over 6 years. In the first year 123 subjects had case-level depression. Three years later 49 (39.8%) of the previously depressed were recovered, 33 (26.8%) were depressed, 16 (13%) were not available for interview and 25 (20.3%) were dead. This study looks at factors associated with the 3-year outcome of patients who were depressed at year 0. Two outcome groups that were compared were a recovered depression group and a recurrent/persistent depression group. The factors that were significantly associated with a recurrence of depression (or persistent depression) at year 3 were bereavement of a close figure in the 6 months before interview, loneliness and life dissatisfaction at year 3. A variety of traditional risk factors for depression (including age, marital status, physical ill-health and incapacity) failed to attain significance in predicting recurrent or persistent depression. When combined, both recovered and recurrently depressed groups at year 3 had significantly higher levels of pain and a higher number of serious upsets in the past 6 months and 6 weeks compared to a compared to a control group. The depressed at year 0 were more likely to have entered more dependent forms of accommodation by year 3. 相似文献
80.
P. Pradat 《European journal of epidemiology》1992,8(6):789-796
This paper reports the results of a case-control study of major congenital heart defects (CHD) in Sweden. During the period 1981–1986, 1,324 such cases were identified and 2,648 controls were selected. Some common maternal characteristics and exposures were studied using information from prospectively collected data. Possible associations with CHD were found for previous perinatal death, maternal diabetes, epilepsy, hydramnios and disproportion between fetus and pelvis. More specific associations were observed between previous spontaneous abortion, epilepsy, hydramnios and truncus anomalies and between diabetes and septal anomalies. However, no associations were found with involuntary childlessness, contraceptive use, or smoking.Abbreviations ASD
atrial septal defect
- CHD
congenital heart defect
- CI
confidence interval
- CoA
coarctation of the aorta
- DORY
double outlet right ventricle
- ECD
endocardial cushion defect
- HLHS
hypoplastic left heart syndrome
- IUD
intrauterine device
- LMP
last menstrual period
- OC
oral contraceptive
- OR
odds ratio
- PDA
patent ductus arteriosus
- TGV
transposition of the great vessels
- VSD
ventricular septal defect 相似文献