脂必妥胶囊联合疏肝祛瘀中药治疗脂肪肝的临床观察

[目的]探讨脂必妥胶囊联合疏肝健脾、化痰祛瘀中药治疗脂肪肝的临床疗效。[方法]将45例脂肪肝患者随机分为两组,治疗组25例,使用脂必妥胶囊联合疏肝健脾、化痰祛瘀中药治疗3月;对照组20例,单用脂必妥胶囊治疗3月,观察患者治疗前后血清丙氨酸转氨酶（ALT）、甘油三酯（TG）、血清总胆固醇（TC）的变化。[结果]治疗组总有效率为84.0%,而对照组仅70.0%;治疗组TG、TC治疗后下降明显;治疗后与对照组治疗后比较也下降明显。[结论]脂必妥胶囊联合疏肝健脾、化痰祛瘀中药治疗脂肪肝是一种有效的方法。     

Femoral pseudo-hernias

Before surgical intervention in the femoral area, doctors should be mindful of two situations in which surgery is not indicated and, in fact, may cause harm. Electronic Publication     

我国部分地区和民族人血清胆固醇酯脂肪酸组成的研究

本文分析了我国5个地区4个民族共113名成年男性血清胆固醇酯脂肪酸组成及血脂水平。不同地区和民族人血清胆固醇酯脂肪酸组成的基本特点一致。但也有一定差异,这些差异与膳食性质有关。文中讨论了血清胆固醇酯脂肪酸组成与饮食脂肪的质和量及血脂水平的关系,并比较了我国与欧美国家人血清胆固醇酯脂肪酸组成。     

HD-91-2型肝病治疗仪治疗脂肪肝24例临床观察

[目的]探讨脂肪肝有效治疗方法。[方法]采用HD-91-2型肝病治疗仪、中药穴位透入、推按运经治疗脂肪肝24例。[结果]总有效率为91.67%。[结论]HD-91-2型肝病治疗仪作为一非药物治疗脂肪肝又一途径,是值得临床推广。     

Central fat predicts deterioration of insulin secretion index and fasting glycaemia: 6-year follow-up of subjects at varying risk of Type 2 diabetes mellitus.

AIMS: To examine the relationships between body composition and changes in fasting glycaemia, and in indices of insulin secretion and insulin action over 6 years in females with a family history of Type 2 diabetes with or without prior gestational diabetes ('at risk' group, AR) and control females (control group, C). METHODS: At baseline and at follow-up, an oral glucose tolerance test and dual energy X-ray absorptiometry assessment of body composition were performed. Indices of insulin resistance (HOMA R') and insulin secretion (HOMA beta') were obtained from fasting insulin and glucose concentrations. RESULTS: At baseline, the groups were similar for age, body mass index, fasting levels of plasma glucose and insulin, HOMA R' and HOMA beta'. Despite similar total body fatness, AR had significantly greater waist circumference and central fat (both P < 0.02) compared with C. At follow-up there was a significant increase in central adiposity only in AR, and the fasting plasma glucose (FPG) level was higher in AR compared with C (5.0 +/- 0.2 vs. 4.3 +/- 0.2 mmol/l, P = 0.02). This rise in plasma glucose in AR was related to a decline in HOMA beta' (r = 0.45, P = 0.0065). Both the baseline and the increments in total and central abdominal fat mass were associated with the time-related decline in HOMA beta'. CONCLUSIONS: Six years after initial assessment, AR showed deterioration in FPG levels due predominantly to a decline in insulin secretion index without major change in insulin resistance index. Importantly, baseline body fatness (especially central adiposity), as well as increases in fatness with time, were the major predictors of the subsequent decline of insulin secretion index and the consequent rise in FPG.     

颊脂体的外科解剖及其临床意义

对30侧成人颊脂体的形态，位置和血液供应进行了观测。颊脂体血供为多源性，主要血管蒂为上颌动脉的颊动脉和面动脉的颊支。依据上述血管蒂的解剖学走向和分布，颊脂体转位可修复邻近的颌面部和口腔软组织缺损。     

Short-term suppression of plasma free fatty acids fails to improve insulin sensitivity when intramyocellular lipid is elevated.

AIMS: Metabolic responses to manipulation of the plasma free fatty acid (FFA) concentration were assessed in six healthy men via cross-over design to determine whether FFAs independently influence insulin sensitivity. METHODS: Intramyocellular lipid (IMCL) was measured by proton magnetic resonance spectroscopy and insulin sensitivity via frequently sampled intravenous glucose tolerance test (IVGTT) after 67 h of two identical low carbohydrate/high fat (LC) diets which were used to elevate IMCL and plasma FFAs. To uncouple the influence of FFAs and IMCL on insulin sensitivity, FFAs were suppressed 30 min prior to and during IVGTT in one treatment [LC + nicotinic acid (NA)] by NA ingestion. RESULTS: Vastus lateralis IMCL was significantly elevated in LC (13.3 +/- 1.1 x 10(-3)) and LC + NA (13.5 +/- 1.1 x 10(-3)) (P < 0.01 for both), but was not different between conditions (P > 0.05). Plasma FFAs were raised in LC (0.79 +/- 0.08 mmol/l) and LC + NA (0.80 +/- 0.11 mmol/l) (P < 0.01 for both) and were significantly reduced by NA ingestion prior to (0.36 +/- 0.05 mmol/l, P < 0.01) and during IVGTT (P < 0.05) in LC + NA. Despite marked differences in plasma FFA availability, insulin sensitivity and glucose tolerance were not different between LC and LC + NA (P > 0.05 for both). CONCLUSIONS: Plasma FFAs appear to exert no immediate effect on insulin sensitivity/glucose tolerance independent of their action on intracellular lipid moieties. Further research is required to elucidate the duration of FFA suppression required to restore insulin sensitivity following lipid-induced insulin resistance.     

Resection and augmentation of Bichat's fat pad in facial contouring

Summary The Bichat's fat pad (Corpus adiposum buccae) is of great significance in facial contouring. Resection of major parts of this fat pad results in hollow cheeks and in accentuation of the zygoma. On the other hand, hypoplasia or shrinkage of this fat pad can be augmented by means of silicone implants for improved aesthetic results.