首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   3892篇
  免费   450篇
  国内免费   76篇
耳鼻咽喉   16篇
儿科学   52篇
妇产科学   62篇
基础医学   241篇
口腔科学   48篇
临床医学   638篇
内科学   711篇
皮肤病学   66篇
神经病学   248篇
特种医学   179篇
外国民族医学   1篇
外科学   712篇
综合类   334篇
现状与发展   1篇
预防医学   379篇
眼科学   26篇
药学   473篇
  6篇
中国医学   67篇
肿瘤学   158篇
  2024年   5篇
  2023年   85篇
  2022年   159篇
  2021年   195篇
  2020年   203篇
  2019年   209篇
  2018年   188篇
  2017年   198篇
  2016年   147篇
  2015年   201篇
  2014年   267篇
  2013年   394篇
  2012年   236篇
  2011年   215篇
  2010年   187篇
  2009年   171篇
  2008年   136篇
  2007年   103篇
  2006年   95篇
  2005年   113篇
  2004年   89篇
  2003年   104篇
  2002年   85篇
  2001年   83篇
  2000年   83篇
  1999年   56篇
  1998年   52篇
  1997年   46篇
  1996年   46篇
  1995年   24篇
  1994年   35篇
  1993年   27篇
  1992年   30篇
  1991年   19篇
  1990年   30篇
  1989年   15篇
  1988年   16篇
  1987年   3篇
  1986年   16篇
  1985年   13篇
  1984年   9篇
  1983年   9篇
  1982年   7篇
  1981年   5篇
  1980年   6篇
  1979年   2篇
  1976年   1篇
排序方式: 共有4418条查询结果,搜索用时 15 毫秒
71.
Dual-mobility sockets were introduced in the United States in 2010. The smaller inside diameter head offered the potential advantage of lower wear and the larger outside diameter head offered the potential advantage of improved stability. Initially, indications were advocated for patients with increased instability risk. However, with larger diameter metal-on-metal articulations falling out of favor, the indications for dual-mobility components are expanding. The author has used this design in over 400 primary THAs with only one dislocation. One loose cup was revised. Dislocation of the smaller femoral head from the larger polyethylene head remains a theoretical risk with DM designs.  相似文献   
72.
ABSTRACT

This study evaluated the efficacy of the Literacy-Free 12 Step Expressive Arts Therapy© curriculum in enhancing personal change and treatment outcomes for populations dually diagnosed with substance use and mental health disorders. It supplemented standard rehabilitation treatment for 47 individuals in a U.S. facility by incorporating 12 Step guidelines, cognitive behavioral therapy, rational emotive behavior therapy, and expressive arts activities. Pre-session and post-session participant ratings revealed positive increases for commitment to recovery, attitude toward making lifestyle changes, and hopefulness. Compared to 101 inpatients at the same facility, curriculum participants evidenced less drop-out, higher treatment completion, and greater personal investment in recovery.  相似文献   
73.
Background: Individuals with co-occurring disorders tend to avoid interaction with others. To instill hope, legacy intervention aims to highlight past experiences while managing life stressors for a positive outlook. Participants take part in legacy activities—crafting tangible projects and recording one's life events—in order to actualize a personal sense of legacy. Objectives: This pre-posttest research tested whether legacy intervention in a partial hospital program (PHP) on reframing past experiences through creative activities could increase life satisfaction and self-efficacy among adults with co-occurring substance misuse and mental health symptoms. Method: Eighty consented patients with co-occurring disorders were randomly assigned to two groups with 62 participants continuing: 37 in legacy intervention (LI) and 25 in partial hospital program only (PHP-only). LI participants were engaged in both PHP and legacy activities. Ten group sessions were held over the course of five weeks for cohorts of 10–15 adult patients in each intervention. Sense of legacy was measured to ensure that LI patients received the appropriate legacy dosage. Results: With RANOVA analyses between and among three time points, life satisfaction was significantly higher in the LI group with group interaction effect over time. In terms of self-efficacy, both groups showed positive changes but no significant difference could be found between the two groups over time and the interaction (time X group) effect was not significant. Importance: The legacy definitions gathered from the LI group were consistent with existing literature and showed three additional themes: children's involvement, concreteness, and life continuation after death.  相似文献   
74.
A hypercoagulable state has, in observational studies, been associated with increased risk of thromboembolic events. The aim of this trial was to study whether dual antiplatelet therapy (DAPT) with clopidogrel in addition to aspirin could reduce the rate of graft occlusions, thromboembolic events, and death compared to aspirin monotherapy in hypercoagulable patients undergoing coronary artery bypass surgery. A total of 1683 patients were screened for eligibility, among which 165 patients were randomized and 133 patients underwent multislice computed tomography scan to evaluate their grafts. Thrombelastography (TEG) and multiplate aggregometry were performed before and after surgery, and again at three months follow up. TEG hypercoagulability was defined as the maximum amplitude above 69 mm. At three months follow up, 17 out of 66 (25.7%) DAPT patients and 15 of 67 (22.4%) aspirin patients had significant graft stenosis or occlusions (p = 0.839). Saphenous vein grafts (SVGs) were stenosed or occluded in 15 (22.7%) patients in the DAPT group and 7 (10.4%) in the aspirin group (p = 0.167). Thromboembolic events and death after the second postoperative day (when clopidogrel was started) were numerically, but not statistically, lower in the DAPT group, 3 (3.8%) vs. 8 (9.9%), p = 0.211. In univariate logistic regression analysis, only postoperative day 4 platelet response to aspirin measured with multiplate was correlated with graft occlusion, OR 1.020 [1.002–1.039], p = 0.033. This is the first trial to test the hypothesis of intensified antiplatelet therapy in hypercoagulable patients. Due to the low enrollment and high loss to follow up, our results can only be viewed as hypothesis generating. We found a high rate of graft occlusions in this patient population. Our results were not suggestive of that DAPT improved saphenous vein graft patency. A trend was observed in patients on DAPT toward fewer MI and deaths. Postoperative response to aspirin therapy was found to be associated with early SVG occlusion.  相似文献   
75.
Coronary heart disease (CHD) is one of the leading causes of morbidity and the most common cause of death in older adults. Paradoxically, elderly patients tend to be systematically excluded from randomized-controlled cardiovascular trials, which complicates decision-making in this population. Management of CHD in the elderly is frequently more difficult in virtue of chronic comorbid conditions and aging-intrinsic dynamics. Despite these challenges, the number of elderly and very elderly patients undergoing percutaneous coronary interventions (PCI) is increasing. Elderly patients in many registries and large clinical series exhibit even a greater benefit from interventional procedures than younger patients, but they have a higher rate of overall complications. We present an overview of the current available evidence of PCI in older adults with stable and unstable CHD, including comparisons between drug-eluting and bare-metal stents, transfemoral and transradial access, and methods of revascularization. Adjuvant antiplatelet and antithrombotic therapies are also discussed.  相似文献   
76.
77.
目的通过“一带一路”重点口岸蚊虫专项监测,了解西南口岸蚊虫种群构成及变化,为口岸蚊媒传染病防控提供科学依据。方法分别在2018年、2019年夏季于广西东兴、云南瑞丽和磨憨3个口岸,采用灯诱法、吸蚊器法采集成蚊,形态鉴定后,记录蚊种和数量。结果2018年、2019年3个口岸共捕获成蚊90156只,经鉴定隶属3亚科7属31种:按蚊属11种共9645只,占10.70%;库蚊属10种共71312只,占79.10%;伊蚊属6种共4597只,占5.10%;阿蚊属1种共1852只,占2.05%;曼蚊属1种2658只,占2.95%;轲蚊属1种2只,占0.002%;巨蚊属1种90只,占0.10%。3个口岸的蚊种为:东兴16种、瑞丽13种、磨憨23种。2018年共捕获成蚊7属28种,2019年共捕获成蚊6属19种,但黑点库蚊(磨憨1只)、埃及伊蚊(瑞丽1只)、多斑按蚊(磨憨30只)只在2019年监测到。三带喙库蚊在东兴口岸占78.29%(17300只),瑞丽口岸占94.24%(36310只),磨憨口岸占52.43%(15481只)。结论应将蚊虫专项监测与本底监测相结合,防止乙脑、疟疾、登革热等蚊媒传染病的跨境传播。  相似文献   
78.
A cross-sectional analysis was performed to explore the relationship between regional body fat distribution and blood pressure in non-obese subjects with different status of blood pressure. Dual-energy X-ray absorptiometry was performed to measure fat mass. Obesity was defined as present body fat ≥25% in males and ≥35% in females. The ratio of leg fat mass to total fat mass (L/T) decreased gradually while the ratio of trunk fat mass to total fat mass (Tr/T) increased gradually with the increasing blood pressure for both genders in non-obese subjects (P < .01), which was consistent with the change in obese ones; and the blood pressure status in the low Tr/T + high L/T group was better than that in the high Tr/T + low L/T group, obviously. After adjustment for confounding factors, blood pressure was still positively related with Tr/T but negatively associated with L/T in non-obese groups. A multiple linear regression analysis showed that L/T was the major negative factors of blood pressure in the non-obese population. Abnormal fat distribution also exists in non-obese subjects with high blood pressure; compared to trunk fat, leg fat may be a more important factor against blood pressure.  相似文献   
79.
All helping professionals risk participation in “dual relationships.” But in the case of former substance users working as counselors, specific dilemmas and problems are accentuated. A qualitative analysis highlights some of the ethical and personal dilemmas faced by these counselors. The data are derived from an interview study initiated in 2000 in Denmark on former substance users with 4–8 years of abstinence. Through an analysis of interview data from a larger group of former substance users, it became evident that those working as counselors experienced specific dilemmas and problems. The current article is based on individual reports of five counselors with recovery status.  相似文献   
80.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号