表现为播散性丘疹型的皮肤型窦组织细胞增生症一例

患者男,54岁,全身红色丘疹、结节及斑块4个月。皮损初发于双下肢,渐波散至全身。查体示全身密集分布的红色丘疹、结节,孤立或呈环形、条带状分布,直径0.3~2.5 cm,质地较硬,略有压痛,有浸润感;皮损大致对称分布,以四肢伸侧、面颊部为著。组织病理示真皮内弥漫性组织细胞浸润,多个具有分枝的肥大的组织细胞及多核巨细胞浸润,灶性浆细胞、淋巴细胞、中性粒细胞浸润,少许嗜酸粒细胞浸润,有细胞伸入现象。免疫组化检查示肥大的组织细胞及多核巨细胞CD68、CD163、S-100蛋白均阳性,CD1a阴性。诊断:皮肤型窦组织细胞增多症。给予复方甘草酸苷口服及卡介菌多糖核酸肌内注射1个月,皮损部分消退。     

延长的跗骨窦切口置入钢板内固定治疗Sanders Ⅱ、Ⅲ型跟骨骨折

目的：探讨经延长的跗骨窦切口置入跟骨钢板内固定治疗SandersⅡ、Ⅲ型跟骨骨折的临床疗效。方法自2013年3月至2015年4月,我院在原跗骨窦入路基础上采用切口延长的办法,置入钢板内固定治疗跟骨关节内骨折29例（37足）,其中男21例,女8例;年龄为19~55岁,平均30.3岁。骨折按Sanders分型：Ⅱ型26足,Ⅲ型11足。根据Essex?Lopresti分型,均为伴有明显移位的跟骨关节外骨折。将手术前后的跟骨高度、宽度、长度、B?hler角和Gissanes角进行比较,术后半年按Maryland足部功能评分系统评价疗效。结果本组29例均获得随访,随访时间为6~18个月,平均8.2个月。术后无切口并发症发生;骨折愈合时间为3~6个月,平均4.3个月。本组37足术前的跟骨高度、宽度、长度、B?hler角以及Gissanes角分别为（34.7±3.4）mm、（38.7±4.6）mm、（65.1±3.7）mm、20.9°±7.5°、99.5°±10.6°;术后1周时的各项数值分别为（38.1±2.2）mm、（33.4±2.7）mm、（67.8±4.5）mm、29.8°±4.7°、119.4°±8.4°;手术前后各项指标比较,差异均有统计学意义（均P＜0.05）。术后半年随访时,采用Maryland足部功能评分系统对患足功能进行评价：优25足,良9足,可3足,优良率为91.9%。结论对于跟骨SandersⅡ、Ⅲ型骨折特别是合并跟骨关节外明显移位的骨折,经延长的跗骨窦切口置入跟骨钢板的内固定手术不仅可以获得充分的显露,准确的复位与固定,而且可早期手术并避免切口并发症,弥补了传统手术入路的不足,便于基层医院开展。     

胆道引流管滑脱后窦道闭塞的再通

胆道镜已广泛应用于临床,经窦道胆道镜取石改变了胆道术后残余结石需要行多次手术的弊端,已经成为治疗术后残余结石的理想途径和首选方法[1-3].但是,如不慎致窦道内胆道引流管滑脱,可导致窦道闭塞[4].此时如不能及时再通窦道,则需要进一步行ERCP或手术治疗,很大程度增加了患者的痛苦及医疗费用.2001年7月至2012年5月我院对23例胆道引流管滑脱致窦道闭塞的患者进行了X线监控下导丝引导的气囊扩张窦道再通术,疗效满意.     

开窗植骨与闭合冲压上颌窦底提升同期种植的临床研究

目的:研究比较上后牙缺失牙槽嵴高度不足患者,根据上颌窦底牙槽嵴骨高度不同,选用开窗植骨或闭合冲压提升上颌窦底,同期种植牙的治疗效果。方法:43例(55侧)上后牙缺失患者,其中34例(40侧)窦底牙槽嵴骨高6~10 mm者行闭合冲压上颌窦底提升术,其余9例(15侧)骨高2~5 mm者行开窗植骨上颌窦底提升手术,均同期完成一期种植体植入手术。结果:所有患者术后未出现上颌窦炎症,9例行开窗植骨上颌窦底提升手术的患者,无窦膜穿孔,平均提升窦底高度5.8 mm,26颗种植体平均负载30个月,种植体稳定,骨结合状况良好。34例行闭合冲压上颌窦底提升术的患者,平均提升窦底高度4.3 mm,手术操作中有3颗发生可察觉窦膜破孔,发生率为4.1%(3/73),在73颗种植体中,有2颗种植体失败,71颗种植体平均负载23个月,种植体稳定,未见明显骨吸收,成功率97.3%(71/73)。结论:闭合冲压上颌窦底提升术是一种微创、简单、可靠用于上颌后牙上颌窦底牙槽嵴骨高度不足的种植临床技术,临床上应根据上颌窦底牙槽嵴骨高度不同,选用开窗植骨或闭合冲压提升上颌窦底。     

An unusual and life-threatening cause of epigastric pain presenting to the general surgical team: a case report

As general surgeons, we are regularly referred patients with epigastric pain. There are a huge number of common pathologies which cause this complaint, most of which are gastrointestinal in origin. Although the old adage goes ’common things are common’, we must always keep our minds open to the possibility of the uncommon and not miss warning signs which are present in the history or examination. We present the case of a 59-year-old woman with a ruptured sinus of Valsalva aneurysm presenting to the accident and emergency department as epigastric pain.     

Coronary Sinus Obstruction after Atrioventricular Canal Defect Repair

The coronary sinus can become obstructed with any instrumentation at or near the ostium such as in atrioventricular canal defect repairs. This complication may lead to a wide range of consequences including dyspnea, angina, myocardial infarction, and sudden death. The following report illustrates the importance of careful perioperative echocardiographic evaluation of the coronary sinus in procedures that may affect the sinus and its ostium.     

Sinus histiocytosis with massive lymphoadenopathy (Rosai-Dorfman disease). Clinico-pathological analysis of a paediatric case

Histochemical and immunohistochemical studies performed in only a few cases of sinus histiocytosis with massive lymphoadenopathy (SHML) indicated that SHML cells belong to themacrophage — histiocyte system, though their exact origin is still uncertain. We analyzed the morphological, antigenic and enzymatic characteristics of the histiocyte-like cells in one paediatric case of SHML (also named Rosai-Dorfman disease). The SHML cells expressed the S-100 protein, lectins concanavalin A, peanut agglutinin andmonocyte-macrophage related antigens CD 11c, CD 14, CD 33, CD 68 and LN 5. Reactivity with other anti-macrophage antibodies (MAC 387, lysozyme, alpha-1 anti-chymotrypsin) was variable. The CD1a antigen was present only in scattered cells, whereas HLA-DR and the HLA-DR associated invariant chain were absent. Cytochemistry demonstrated an intense activity of acid phosphatase and non specific esterase of SHML cells. A large amount of medium sized mononuclear cells were located in the sinuses and intersinusoidal tissue. Our findings suggest that SHML cells have intermediate features between phagocytes and Langerhans cells/interdigitating reticulum cells. The heterogeneity of marker expression on SHML cells might be related to the local content of factors (e.g., cytokines), capable of modulating the phenotype of monocyted and derived cells.     

Sinus tachycardia in term infants preceding sudden infant death

The quantities of sinus tachycardia in 24-h recordings of the electrocardiogram from 16 full-term infants (37 weeks gestation) who were subsequently victims of the sudden infant death syndrome (SIDS), from 230 randomly selected age-matched full-term survivors and from 64 full-term survivors matched for age and birth weight were measured by computer and manual analysis techniques. Of 16 infants dying of SIDS, 7 had elevated levels of sinus tachycardia (>95th centile in controls) (P<0.01). Although high levels of sinus tachycardia might be of value in identifying infants at high risk of SIDS, these encouraging findings must first be validated by further prospective studies.Abbreviations IHR instantaneous heart rate - SIDS sudden infant death syndrome - ECG electrocardiogram     

功能性内窥镜鼻窦手术在老年患者的应用

目的 探讨功能性内窥镜鼻窦手术在老年慢性鼻窦炎、鼻息肉患者的应用及其疗效。方法 总结74例≥岁老年慢性鼻窦炎、鼻息肉患者行功能性内窥镜手术的临床资料,以同期行相同手术的199例59岁以下患者为对照组。结果 老年组与对照组手术治愈率分别为79．5％和77．9％。结论 功能性内窥镜鼻窦手术同样适合于老年患者,可望提高老年患者的生存质量。