Clinical Evaluation of a New Self-Drying Silicone Gel in the Treatment of Scars: A Preliminary Report

Topical silicone gel sheeting and intralesional steroids are the only evidence-based recommendable forms of treatment to control the quality of a scar. The advantages and disadvantages of both are well known. This study was undertaken to verify the efficacy of a new topical silicone treatment: a self-drying spreadable gel that needs no means of fixation and cannot be seen because of complete transparency. Fresh surgical scars treated with the tested product showed significantly better outcomes than those untreated in a prospective trial involving a group of 160 patients. Patient compliance was particularly good, especially for scars on exposed areas such as the face, where the traditional gel sheeting is frequently discontinued at an early stage by patients who object to its visibility. The results of the self-drying silicone gel have indeed been satisfactory. Considering the effective results obtained and the good patient compliance, the authors currently rate this concept of treatment as the first choice for preventing hypertrophy of recent scars.     

硅油长期填充眼的临床观察

目的 观察硅油长期填充眼的病情转归、并发症及预后.方法 回顾性系列病例研究.收集1992至2005年间行硅油填充且未取出硅油达2年以上的36例(37只眼)患者临床资料,进行回顾性分析.其中男性30例(31只眼),女性6例(6只眼).年龄最小1岁零2个月,最大73岁.硅油填充时间2至13年.37只眼均为开放性眼球损伤,其中眼球破裂伤24只眼,球内异物伤5只眼,贯通伤3只眼,穿通伤5只眼.采用三通道玻璃体切除、视网膜切开及切除、眼内激光光凝、硅油填充等手术.结果 手术后硅油下视网膜良好复位13只眼(35.1%),部分复位11只眼,硅油下视网膜仍然脱离7只眼.视力达0.01以上者9只眼(24.3%),最佳视力为0..1.长期随访发现的并发症:角膜带状变性13只眼(35.1%),角膜全混浊6只眼,硅油乳化17只眼(45.9%),继发性青光眼2只眼,晶状体混浊4只眼;无明确硅油并发症8只眼(21.6%).结论 对重症眼外伤患者确无有效疗法时,长期行眼内硅油填充仍可获得视网膜复位或维持眼球外观的机会.     

可控式眼内硅油吸引器的制作及临床应用

探讨眼内硅油取出的有效方法，研究视网膜复位眼的硅油取出手术效果。方法作者研制了一种可控式眼内硅油取出装置，并应用于４３例４４只眼内硅没取出手术。结果：本装置由吸引针头，手柄，引流和负压源四部分组成；采用普通持续负压源作为吸引动力，通过一个手指标按压手柄上的进气孔来控制全部吸引过程。术中在６－１５分钟内将硅油整体吸出。     

小梁切除联合睫状体平坦部造瘘治疗绝对期青光眼研究

目的：研究绝对期青光眼消除症状，保留眼球的治疗方法。方法：对20例20眼绝对期青光眼患者采用小梁切除联合睫状体平坦部造瘘置硅胶管手术。结果：绝大多数患者症状消除，眼压下降。结论：本文设计的方法效果良好。对术后硅胶管裸露的预防值得进一步深入研究。     

Development of an Intravascular Pumping Oxygenator Using a New Silicone Membrane

Abstract: A new intravascular pumping oxygenator (IVPO) was developed for intravascular gas exchange and circulatory assistance in critically ill patients with respiratory and circulatory failure. The IVPO utilizes new silicone hollow fibers (diameter. 1 mm: membrane width, 50 μm) and consists of two driving tubes for the oxygenation and pumping of circulating blood. The performance characteristics of the IVPO were studied using an experimental ex vivo model. With a mean hemoglobin concentration of 10.5 ± 2.3 g/dl, total oxygen transfer was 5.6 ± 1.5 ml/min at a blood flow of 200 ml/min and 6.3 ± 2.2 ml/min at a blood flow of 250 ml/min. Total CO₂ transfer was 3.8 ± 1.4 ml/min at a blood flow of 200 ml/min and 4.2 ± 1.6 ml/min at a blood flow of 250 ml/min during IVPO pumping. This preliminary experiment demonstrated that the IVPO has the capacity to function both as a circulatory assist pump and as an intravascular hollow fiber oxygenator.     

视网膜脱离硅油充填术继发性青光眼临床观察

目的 探讨视网膜脱离硅油充填术继发性青光眼的相关因素及硅油取出对继发性青光眼的影响。方法 统计玻璃体切除硅油充填术视网膜复位后行硅油取出的病例，并对继发性青光眼的发生及其转归进行了随访观察。结果 120例121眼中25眼发生继发性青光眼(20．66％)，硅油取出后经1-3月随访23眼眼压降至正常，2眼药物控制。结论 随着硅油在眼内停留时间的延长继发性青光眼的发生率明显增加，玻璃体切除硅油充填术后以在视网膜复位后3-6月取出为宜。一旦发生继发性青光眼即是硅油取出的指征。     

Genitourinary spheroidal membrane (GSM) for the treatment of female stress urinary incontinence

Fourteen female patients with stress urinary incontinence were implanted with the genitourinary spheroidal membrane (GSM) device (Bard), a percutaneous implantable spheroidal membrane for the treatment of urinary incontinence through localized tissue expansion. Most patients had undergone previous pelvic surgery and suffered from significant medical problems. The placement of the GSM was performed under local anesthesia, with the help of fluoroscopy, cystoscopy and digital examination. The GSM was inserted and inflated close to the posterior urethra, causing its coaptation. Mean patient follow-up is 33 months. Eight patients are now completely dry (57.1%) and 2 are significantly improved (14.3%), with a success rate of (71.4%). The remaining 4 patients (27.6%) are considered failures. Migration of the GSM into the bladder was noticed on three occasions. Two extrusions into the vaginal wall were encountered. GSM replacements were performed without ill effects. Preliminary findings suggest that the GSM prosthesis may be a simple and safe alternative for the treatment of female stress urinary incontinence. The device is still in the experimental stage and further studies in Europe have been started.     

Mandibular angle implants

A new type of implant designed to increase the angle of the mandible in three dimensions is described. Made of silicone and shaped like a saddle, this implant makes the technique of implantation relatively simple, and its versatility makes it a desirable addition to the tools for skeletal framework reconstruction of the face. The satisfaction rate has been high and the complications easy to manage. The surgical technique consists of an intraoral incision and the development of a subperiosteal pocket at the mandibular angle area, often performed under local anesthesia.     

Vasculitis following implantation of a ventriculoperitoneal shunt tube made of silicone

 A 56-year-old man presented with hyperproteinemia and renal dysfunction associated with antineutrophil cytoplasmic antibodies (ANCA). He had had a ventriculoperitoneal shunt tube made of silicone implanted 4 years earlier. In his renal biopsy, necrotizing crescentic glomerulonephritis was identified: tests for both myeloperoxidase ANCA and proteinase 3 ANCA were initially weakly positive. Antinuclear and other autoantibodies were also present. We diagnosed ANCA-associated vasculitis, probably induced by the silicone tube. Received: December 19, 2001 / Accepted: June 11, 2002 Correspondence to:M. Mukai     

两种消毒剂在口腔硅橡胶印膜消毒应用中效果对比分析

目的比较两种消毒剂在口腔硅橡胶印模消毒中的效果。方法取上下颌75对(150个)样本随机选择25对样本作为阳性对照组,剩余的50对样本随机分为实验1组(采用2%戊二醛消毒剂浸泡消毒)和实验组2组(采用1%84消毒剂浸泡消毒)各25对(50个),比较两组的消毒效果,并于浸泡前后测量基牙的远近中径(MD)、颊舌径(BL)、牙合龈距离(OG)三个面的尺寸以确定硅胶印模材的形变。结果实验1组消毒的样本50个,有菌群生长1个,合格率为98%,实验2组消毒的样本50个,有菌群生长9个,合格率为82%,两组比较差异有统计学意义(P0.01)。在浸泡后实验1组有2个模型的形变超过2%,实验2组有12个模型的形变超过2%,两组比较差异有统计学意义(P0.01)。结论 2%戊二醛消毒剂对口腔硅橡胶印模材料的消毒效果优于1%84消毒剂,且产生的形变更少。