Immediate stent recoil in an anastomotic vein graft lesion treated by cutting balloon angioplasty

Saphenous vein graft (SVG) anastomotic lesions can have significant fibromuscular hyperplasia and may be resistant to balloon angioplasty alone. Stents have been used successfully to treat these lesions. There are no reports of immediate stent recoil following such treatment in the literature. We describe immediate and persistent stent recoil in an anastomotic SVG lesion even after initial and post-deployment complete balloon dilatation of the stent and its successful treatment by cutting balloon angioplasty.     

门静脉高压症脾切除术后持续性发热原因的探讨

目的探讨门静脉高压症脾切除术后持续性发热的原因。方法回顾性分析我院2005至2010年收治的136例因门静脉高压症行脾切除术病例的临床资料,观察术后持续性发热与肝功能、术后并发症的关系。结果 136例门静脉高压症行脾切除术患者中,持续性发热42例（30.9%）,并发症的发生率27.2%。结论门静脉高压症脾切除术后持续性发热原因主要与肝功能相关,与术后并发症无明确相关。     

PTVE联合PSE双介入治疗肝硬化并门脉高压、脾功能亢进

目的:观察经皮经肝胃冠状静脉栓塞术(percutaneous transhepatic variceal embolization,PTVE)联合部分脾栓塞术(partial splenic embolization,PSE)的双介入栓塞术治疗肝硬化并门脉高压及脾功能亢进的临床疗效。方法:10例肝硬化并门脉高压、脾功能亢进患者,给予PTVE治疗预防出血,3～7 d后,再行PSE降低门脉压及改善脾功能亢进。随访3月,观察止血率、再出血率、血象、肝功能、胃镜及并发症等指标。结果:10例患者中8例完成栓塞治疗及后续PSE治疗,2例急性出血患者迅速止血。随访3月,全部病例肝功能改善、血细胞回升至正常水平,无再出血和严重并发症发生。其中3例胃镜复查显示2例食管胃底静脉曲张均减轻,1例消失。结论:PTVE联合PSE的双介入栓塞术治疗肝硬化并门脉高压及脾功能亢进疗效确切,安全性好,值得临床推广。     

对比剂流率对门静脉CT血管造影质量的影响研究

目的:探讨不同对比剂流率对肝门静脉(Portal vein,PV) CT血管造影质量的影响,为优化门静脉CT血管成像技术提供临床依据.方法:选择2010年7月～2012年7月期间我院收治的80例接受肝门静脉多层螺旋CT上腹检查的患者为研究对象,按数字表法随机分为三组,分别为27例、27例、26例.前臂静脉注射对比剂碘比醇,浓度为300 mgI/mL,A组流量为2.0 mL/s,B组3.0 mL/s,C组4.0 mL/s.采用对比剂自动跟踪激发扫描技术进行扫描,分析比较三组的成像质量.结果:A组、B组、C组随着对比剂流量的增加,造影图像质量逐渐提高,且三组比较具有显著性差异(x2=12.979,P＜0.05).其中,C组造影质量评价得分情况明显优于A组(x2=11.334,P＜0.05);而C组与B组相比,B组与A组相比无显著性差异(P＞0.05).A组、B组、C组随着对比剂流量的增加,PVCT值、肝实质CT值、PV-肝实质CT值均逐渐增加.三组的PVCT值、PV-肝实质CT值比较具有显著性差异(t=6.989,P＜0.05),而肝实质CT值比较无显著性差异(P＞0.05).C组的PVCT值、PV-肝实质差明显高于A组(t=10.612、9.745,P＜0.05);而C组与B组相比,B组与A组相比无显著性差异(P＞0.05).结论:对比剂注射流率对于患者门静脉CT血管造影图像质量有显著的影响,以4.0 mL/s的对比剂注射流率得出的CT图像质量最佳.     

1.5T磁共振e-THRIVE序列与B-TFE序列肝门静脉成像比较

目的将e-THRIVE序列重建的对比增强肝门静脉系统血管图像和B-TFE序列采集的非对比增强肝门静脉系统血管图像进行比较分析,为1.5T磁共振肝实质动态增强与肝门静脉成像一站式检查的序列选择提供参考依据。方法搜集60例(每一例均完成e-THRIVE序列对比增强肝门静脉成像及B-TFE序列非对比增强肝门静脉成像)病历资料完整的住院患者磁共振血管影像资料,由两位副主任医师分别对同一病例的两组血管图像评分,对得分情况进行Wilcoxon符号秩检验。结果 e-THRIVE序列组无论是评价肝门静脉系统的肝内部分还是肝外部分均优于B-TFE序列组(P肝内<0.01;P肝外<0.01),对肝内部分评价时e-THRIVE序列组的结果客观性更强,对肠系膜下静脉的显示e-THRIVE序列组明显优于B-TFE序列组。结论 1.5T磁共振肝实质动态增强与肝门静脉成像一站式检查通过适当调整检查技术参数,直接利用肝实质动态增强时e-THRIVE序列采集的相关原始数据进行对比增强肝门静脉成像,比在肝实质动态增强前另加一个B-TFE序列进行非对比增强肝门静脉成像更好。     

脾动脉栓塞联合思他宁灌注治疗门脉高压、脾亢的临床观察

目的探讨部分脾动脉栓塞联合思他宁灌注治疗门静脉高压、脾功能亢进的临床效果。方法 60例肝硬化门静脉高压症合并脾功能亢进病人,在一次性操作中先用思他宁灌注,然后进行部分脾动脉栓塞。随访手术前后门静脉压力参数改变、脾功能变化、食管胃底曲张静脉程度改变。结果 60例病人手术操作均成功,门静脉压力从(32.8±2.87)mmHg降到(15.10±1.14)mmHg,门静脉内径从(1.46±0.43)cm回缩到(1.27±0.43)cm,门脉血流量从(1538.51±4.48)mL/min减少到(1208.11±9.28)mL/min,术前术后比较三者差异均有统计学意义,58例术后内窥镜及食道钡餐检查曲张静脉好转。结论脾动脉栓塞联合思他宁灌注治疗门静脉高压、脾功能亢进,可明显降低门静脉压力,改善脾功能亢进,是一种安全、有效的介入治疗方法。     

门静脉-肝静脉瘘的MSCT诊断

目的:探讨门静脉-肝静脉瘘多层螺旋CT(MSCT)表现及诊断价值。方法:回顾性分析5例门静脉-肝静脉瘘患者临床及MSCT资料。结果:5例中4例合并肝硬化、门脉高压,肝左叶3例,右叶2例,病变均位于肝包膜下,增强后门脉期与门静脉同步均匀强化,瘤样扩张血管团将门静脉及肝静脉相连通,CPR及VR清晰、直观显示门静脉-肝静脉瘘血管走行及瘘口局部情况。结论:MSCT及三维后处理技术能显示门静脉-肝静脉瘘特征性表现,可作为首选检查方法。     

静脉留置针在乙肝病毒感染产妇中的应用

目的 探讨静脉留置针在乙肝病毒感染产妇中的应用.方法 通过对313例乙肝表面抗原(HBsAg)阳性待产孕妇进行产时、产后静脉留置针的应用及护理配合,观察静脉留置针的应用效果.结果 本组313例乙肝表面抗原阳性产妇使用静脉留置针,无静脉炎发生,发生皮下血肿7例、液体渗漏10例、导管堵塞4例、敷贴局部反应3例,需重复穿刺21例,产后出血15例.患者满意率达98％以上.结论 静脉留置针安全、简便、易于操作,适用于临床用药和紧急抢救,患者感到满意、舒适.     

Thrombus Localization by Using Streptokinase Containing Vesicular Systems

Our research focused on the preparation of vesicular drug delivery systems, such as liposomes, noisomes, and sphingosomes, for achieving slow release of entrapped proteins in the circulation to increase half-life, to mask immunogenic properties, and to protect against loss of enzymatic activity. We prepared, characterized, and monitored the biodistribution of three types of vesicular systems (liposomes, niosomes, and sphingosomes) containing streptokinase. For biodistribution stuides, radiolabelled streptokinase dispersions were injected into the ear vein of female rabbits in the weight of 2.5–3 kg weight. Following the application, rabbits were sacrificed, then organs of these animals were removed and radioactivity of organs was measured by well-type gamma counter. The comparison of the biodistribution results of the free streptokinase with the streptokinase vesicles showed that incorporation of the enzyme into the vesicles changed the biodistribution of the drug and by the entrapment of the streptokinase in the vesicles, thrombus uptake and imaging quality were improved.     

Outflow thrombus in a left ventricular-assist device: Visualization by CT angiography

A 63-year-old man with ischemic cardiomyopathy, ejection fraction of 15%, and status after HeartMate II implantation as a bridge to cardiac transplantation presented with presyncope and exertional dyspnea 1.5 years after implantation. After unrevealing laboratory workup and echocardiography for LVAD thrombosis, the patient underwent CT imaging. CT revealed mural thrombus in the proximal LVAD outflow cannula, a very unlikely site of thrombus, highlighting the importance of CT imaging in diagnosis of LVAD complications.